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1.
Conn Med ; 61(3): 175-7, 1997 Mar.
Article in English | MEDLINE | ID: mdl-9097488

ABSTRACT

Physicians Care will distinguish itself from competitors in the marketplace through the introduction of products with significant value. Physicians Care is dedicated to working closely with providers to identify the contributions made by each party to the building of product value and to appropriately reward providers for those efforts. The ultimate goal is the development of an insurance company in which physicians are truly invested and committed to best clinical practices and who exercise enhanced autonomy in managing their patient's care with clinical and administrative support from Physicians Care.


Subject(s)
Commerce/methods , Commerce/standards , Health Maintenance Organizations/standards , Physician's Role , Connecticut , Humans
3.
J Neurosurg ; 78(2): 226-32, 1993 Feb.
Article in English | MEDLINE | ID: mdl-8421205

ABSTRACT

A total of 93 patients with intractable spasticity due to either spinal cord injury (59 cases), multiple sclerosis (31 cases), or other spinal pathology (three cases) were entered into a randomized double-blind placebo-controlled screening protocol of intrathecal baclofen test injections. Of the 88 patients who responded to an intrathecal bolus of 50, 75, or 100 micrograms of baclofen, 75 underwent implantation of a programmable pump system for chronic therapy. Patients were followed for 5 to 41 months after surgery (mean 19 months). No deaths or new permanent neurological deficits occurred as a result of surgery or chronic intrathecal baclofen administration. Rigidity was reduced from a mean preoperative Ashworth scale score of 3.9 to a mean postoperative score of 1.7. Muscle spasms were reduced from a mean preoperative score of 3.1 (on a four-point scale) to a mean postoperative score of 1.0. Although the dose of intrathecal baclofen required to control spasticity increased with time, drug tolerance was not a limiting factor in this study. Only one patient withdrew from the study because of a late surgical complication (pump pocket infection). Another patient received an intrathecal baclofen overdose because of a human error in programming the pump. The results of this study indicate that intrathecal baclofen infusion can be safe and effective for the long-term treatment of intractable spasticity in patients with spinal cord injury or multiple sclerosis.


Subject(s)
Baclofen/administration & dosage , Muscle Spasticity/drug therapy , Spinal Cord Diseases/complications , Spinal Cord Injuries/complications , Adult , Aged , Double-Blind Method , Drug Tolerance , Female , Follow-Up Studies , Humans , Infusion Pumps, Implantable/adverse effects , Injections, Spinal , Male , Middle Aged , Multiple Sclerosis/complications , Muscle Spasticity/etiology
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