ABSTRACT
An ambitious U.S. project aims to sample more than 50 animal species to clarify how the COVID-19 virus moves between people and wildlife.
Subject(s)
Animals, Wild , COVID-19 , SARS-CoV-2 , COVID-19/epidemiology , COVID-19/virology , Animals , Animals, Wild/virology , Humans , United States/epidemiologyABSTRACT
Market uncertainties, safety rules, and export worries stand in way of H5N1 shots for cattle.
Subject(s)
Cattle Diseases , Influenza A Virus, H5N1 Subtype , Influenza Vaccines , Cattle , Animals , Influenza Vaccines/administration & dosage , Influenza Vaccines/immunology , Influenza A Virus, H5N1 Subtype/immunology , Cattle Diseases/prevention & control , Cattle Diseases/virology , Cattle Diseases/immunology , Orthomyxoviridae Infections/prevention & control , Orthomyxoviridae Infections/veterinary , Orthomyxoviridae Infections/immunology , Orthomyxoviridae Infections/virology , Birds , Female , Influenza in Birds/prevention & control , Influenza in Birds/virology , HumansABSTRACT
New measures to control H5N1 in cows are "a drop in the bucket," scientists say.
Subject(s)
Cattle Diseases , Dairying , Disease Outbreaks , Influenza A Virus, H5N1 Subtype , Influenza in Birds , Animals , Cattle , Female , Cattle Diseases/virology , Cattle Diseases/epidemiology , Disease Outbreaks/veterinary , Influenza A Virus, H5N1 Subtype/pathogenicity , Influenza in Birds/epidemiology , Influenza in Birds/virology , Influenza in Birds/transmission , United States/epidemiologyABSTRACT
Research consortium announced as new variant spreads in Congolese mining region.
Subject(s)
Disease Outbreaks , Monkeypox virus , Mpox (monkeypox) , Humans , Democratic Republic of the Congo/epidemiology , Disease Outbreaks/prevention & control , Mining , Mpox (monkeypox)/epidemiology , Mpox (monkeypox)/transmission , Mpox (monkeypox)/prevention & control , Monkeypox virus/genetics , Monkeypox virus/isolation & purificationABSTRACT
Veterinarians and researchers say it has taken too long to share data on viral changes, spread, and milk safety.
Subject(s)
Cattle Diseases , Disease Outbreaks , Influenza A Virus, H5N1 Subtype , Milk , Orthomyxoviridae Infections , Animals , Cattle , Humans , Cattle Diseases/epidemiology , Cattle Diseases/prevention & control , Cattle Diseases/virology , Cattle Diseases/transmission , Disease Outbreaks/prevention & control , Milk/virology , Orthomyxoviridae Infections/epidemiology , Orthomyxoviridae Infections/transmission , Orthomyxoviridae Infections/prevention & control , Orthomyxoviridae Infections/virology , United States/epidemiologyABSTRACT
Moderna's pause on Kenya project highlights difficulties in creating a competitive vaccine sector on the continent.
Subject(s)
COVID-19 Vaccines , Kenya , Manufacturing and Industrial FacilitiesABSTRACT
Farm worker becomes infected as H5N1 appears to spread between dairy cows in five states.
Subject(s)
Cattle Diseases , Influenza A Virus, H5N1 Subtype , Influenza in Birds , Animals , Cattle , Female , Humans , Birds , Cattle Diseases/epidemiology , Cattle Diseases/virology , Dairying , Farmers , Influenza in Birds/epidemiologyABSTRACT
Jeanne Marrazzo, an HIV prevention researcher, sees need for more "holistic" approach to community health problems.
Subject(s)
National Institute of Allergy and Infectious Diseases (U.S.) , United StatesABSTRACT
As deadline nears, negotiations continue over sharing pathogen sequences and vaccine doses.
Subject(s)
Global Health , Information Dissemination , International Cooperation , Pandemics , Humans , Pandemics/prevention & control , World Health OrganizationABSTRACT
Strategy of using multiple mRNA shots to hone powerful antibodies hits a pothole.
Subject(s)
AIDS Vaccines , HIV Infections , Skin Diseases , mRNA Vaccines , Humans , AIDS Vaccines/adverse effects , AIDS Vaccines/immunology , Antibodies, Neutralizing/immunology , HIV Antibodies/immunology , HIV Infections/prevention & control , mRNA Vaccines/adverse effects , Skin Diseases/etiology , National Institute of Allergy and Infectious Diseases (U.S.) , United States , Clinical Trials, Phase I as TopicABSTRACT
U.S. agency plans to make inexpensive prevention shots widely available for people at risk.
Subject(s)
Anti-HIV Agents , HIV Infections , Pre-Exposure Prophylaxis , Humans , HIV Infections/epidemiology , HIV Infections/prevention & control , Africa South of the Sahara/epidemiology , Anti-HIV Agents/administration & dosage , Delayed-Action Preparations/administration & dosage , Male , Female , InjectionsABSTRACT
United States and other countries may soon approve virus-proof pigs.
Subject(s)
Animals, Genetically Modified , Disease Resistance , Gene Editing , Meat , Porcine Reproductive and Respiratory Syndrome , Porcine respiratory and reproductive syndrome virus , Animals , Swine/genetics , Swine/virology , Animals, Genetically Modified/genetics , Animals, Genetically Modified/virology , United States , Porcine Reproductive and Respiratory Syndrome/genetics , Disease Resistance/geneticsABSTRACT
Four largely ignored coronaviruses circulate in humans without causing great harm and may portend the future for SARS-CoV-2.
Subject(s)
Coronavirus Infections , Coronavirus , Viral Zoonoses , Humans , COVID-19/epidemiology , COVID-19/virology , Coronavirus/genetics , Coronavirus/isolation & purification , Coronavirus/pathogenicity , Coronavirus Infections/epidemiology , Coronavirus Infections/transmission , Coronavirus Infections/virology , Viral Zoonoses/epidemiology , Viral Zoonoses/transmission , Viral Zoonoses/virology , AnimalsABSTRACT
Infecting captive species could help gauge pandemic risk of coronaviruses that have yet to infect humans.
Subject(s)
COVID-19 , Chiroptera , SARS-CoV-2 , Viral Zoonoses , Animals , Humans , Chiroptera/virology , COVID-19/epidemiology , COVID-19/prevention & control , Phylogeny , Pandemics/prevention & control , Risk , Viral Zoonoses/epidemiology , Viral Zoonoses/prevention & controlABSTRACT
Congo cases suggest viral strain there is spreading sexually, like less lethal one that triggered last year's global outbreak.
Subject(s)
Disease Outbreaks , Homosexuality, Male , Monkeypox virus , Mpox (monkeypox) , Sexually Transmitted Diseases, Viral , Humans , Congo/epidemiology , Mpox (monkeypox)/epidemiology , Mpox (monkeypox)/transmission , Sexually Transmitted Diseases, Viral/epidemiology , Male , Monkeypox virus/genetics , Monkeypox virus/isolation & purification , Monkeypox virus/pathogenicity , Sexual and Gender MinoritiesABSTRACT
CRISPR-engineered herpesviruses can speed spread of genes to viral relatives in mice.
Subject(s)
CRISPR-Cas Systems , Gene Drive Technology , Herpes Simplex , Herpesvirus 1, Human , Animals , Mice , Herpesvirus 1, Human/genetics , Herpes Simplex/prevention & controlABSTRACT
Travelers are first, but the real need is in endemic areas.
Subject(s)
Chikungunya Fever , Viral Vaccines , Humans , Chikungunya Fever/epidemiology , Chikungunya Fever/prevention & control , Travel , Climate ChangeABSTRACT
U.S. government project bets big on intranasal vaccines and monoclonal antibodies, but omits more ambitious approaches.
Subject(s)
Antibodies, Monoclonal , COVID-19 Vaccines , COVID-19 , SARS-CoV-2 , Humans , Antibodies, Monoclonal/administration & dosage , Antibodies, Neutralizing/administration & dosage , Antibodies, Viral/administration & dosage , COVID-19/prevention & control , Government , Administration, Intranasal , COVID-19 Vaccines/administration & dosage , United States Government Agencies , United States , Immunization, SecondaryABSTRACT
Edits to one gene can't completely stop infections, however.
Subject(s)
CRISPR-Cas Systems , Chickens , Gene Editing , Influenza in Birds , Animals , Chickens/genetics , Chickens/virology , Influenza in Birds/genetics , Influenza in Birds/prevention & control , Influenza A virusABSTRACT
Katalin Karikó and Drew Weissman overcame a major roadblock to a novel immunization approach.