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J Diabetes ; 7(5): 664-71, 2015 Sep.
Article in English | MEDLINE | ID: mdl-25266369

ABSTRACT

BACKGROUND: The effects of diabetes on the respiratory system were investigated with arterial blood gas, sleep quality index and respiratory functions tests. METHODS: Fifty-three patients with type II diabetes and 41 healthy cases were included. Their biochemical data, demographic characteristics, anthropometric measurements and echocardiographic findings were collected from polyclinic records. Respiratory function tests were performed for all subjects and Pittsburgh Sleep Quality Index questionnaire was conducted. Aforementioned data were compared between these two groups. RESULTS: The age, body weight and body mass index were similar but oxygen pressure, oxygen saturation, forced vital capacity (FVC; %), and sleep quality were decreased in patients with diabetes. Sleep quality was correlated with the presence of diabetes and hypertension, duration of diabetes, fasting and postprandial blood glucose levels, homeostasis model of assessment-insulin resistance, Glycosylated hemoglobin levels, and FVC. Half of the diabetic patients exhibited respiratory failure during sleep. Especially diabetic patients with autonomic neuropathy, experienced a more severe and prolonged decrease in oxygen saturation. CONCLUSIONS: Blood gas, respiratory functions and sleep quality, which need to be evaluated as a whole, were affected in patients with diabetes. Assessment of sleep and its quality requires special attention in patients with diabetes.


Subject(s)
Diabetes Mellitus, Type 2/physiopathology , Respiration , Sleep/physiology , Adult , Female , Humans , Male , Middle Aged , Respiratory Function Tests , Respiratory Mechanics/physiology
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