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4.
Acta Haematol ; 78 Suppl 1: 190-3, 1987.
Article in English | MEDLINE | ID: mdl-3124446

ABSTRACT

We evaluated the therapeutic efficacy of autologous bone marrow transplantation (ABMT) in 49 patients with acute leukemia, using ex-vivo-treated marrow with mafosfamide. This report summarizes data collected from 8 italian centers, involving 27 cases with acute lymphoid leukemia (ALL) and 22 cases with acute nonlymphoid leukemia (ANLL). The analysis of the results shows that the disease-free survival of ALL and ANLL are similar (45 and 52%, respectively) and no significant difference can be demonstrated between patients transplanted in CR1 or CR2, although there is a trend in favor of ABMT in CR1.


Subject(s)
Bone Marrow Transplantation , Leukemia/therapy , Acute Disease , Adolescent , Adult , Bone Marrow/drug effects , Child , Cyclophosphamide/analogs & derivatives , Cyclophosphamide/pharmacology , Evaluation Studies as Topic , Humans , Preoperative Care , Transplantation, Autologous
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