1.
J Clin Pharm Ther
; 43(2): 273-275, 2018 Apr.
Article
in English
| MEDLINE
| ID: mdl-28833364
ABSTRACT
WHAT IS KNOWN AND OBJECTIVE: Limited data are available on eosinophilia as a drug adverse event. We describe a case of eosinophilia from lenalidomide therapy. CASE DESCRIPTION: A 50-year-old woman received lenalidomide, dexamethasone and cyclophosphamide as POEMS syndrome treatment. Eosinophil count rose during lenalidomide treatment and decreased in the periods off treatment. Naranjo nomogram suggested a probable association between the use of lenalidomide and eosinophilia. WHAT IS NEW AND CONCLUSION: Eosinophilia has rarely been described with lenalidomide. This case shows a clear temporal relationship between lenalidomide and eosinophilia.
Subject(s)
Eosinophilia/chemically induced , Thalidomide/analogs & derivatives , Angiogenesis Inhibitors/therapeutic use , Antineoplastic Agents, Hormonal/therapeutic use , Cyclophosphamide/therapeutic use , Dexamethasone/therapeutic use , Female , Humans , Lenalidomide , Middle Aged , POEMS Syndrome/drug therapy , Thalidomide/adverse effects , Thalidomide/therapeutic use
2.
Farm Hosp
; 37(5): 426-7, 2013.
Article
in Spanish
| MEDLINE
| ID: mdl-24128109
Subject(s)
Arterial Occlusive Diseases/chemically induced , Cytochrome P-450 CYP3A Inhibitors , Ergotamine/adverse effects , HIV Infections/drug therapy , HIV Protease Inhibitors/adverse effects , Ischemia/chemically induced , Migraine without Aura/drug therapy , Ritonavir/adverse effects , Vasoconstrictor Agents/adverse effects , Adult , Anticoagulants/therapeutic use , Arm/blood supply , Arterial Occlusive Diseases/drug therapy , Cytochrome P-450 CYP3A , Drug Combinations , Drug Interactions , Drug Therapy, Combination , Ergotamine/pharmacokinetics , Ergotamine/therapeutic use , Female , HIV Infections/complications , HIV Protease Inhibitors/pharmacokinetics , HIV Protease Inhibitors/therapeutic use , Humans , Inactivation, Metabolic , Ischemia/drug therapy , Microsomes, Liver/drug effects , Microsomes, Liver/enzymology , Migraine without Aura/complications , Ritonavir/pharmacokinetics , Ritonavir/therapeutic use , Thrombolytic Therapy , Vasoconstrictor Agents/pharmacokinetics , Vasoconstrictor Agents/therapeutic use
3.
Farm. hosp
; 37(5): 426-427, sept.-oct. 2013.
Article
in Spanish
| IBECS
| ID: ibc-121002