Rapid development of application-specific flexible MRI receive coils.

Over the last 30 years, there have been dramatic changes in phased array coil technology leading to increasing channel density and parallel imaging functionality. Current receiver array coils are rigid and often mismatched to patient's size. Recently there has been a move towards flexible coil technology, which is more conformal to the human anatomy. Despite the advances of so-called flexible surface coil arrays, these coils are still relatively rigid and limited in terms of design conformability, compromising signal-to-noise ratio (SNR) for flexibility, and are not designed for optimum parallel imaging performance. The purpose of this study is to report on the development and characterization of a 15-channel flexible foot and ankle coil, rapidly designed and constructed using highly decoupled radio-frequency (RF) coil elements. Coil performance was evaluated by performing SNR and g-factor measurements. In vivo testing was performed in a healthy volunteer using both the 15-channel coil and a commercially available 8-channel foot coil. The highly decoupled elements used in this design allow for extremely rapid development and prototyping of application-specific coils for different patient sizes (adult vs child) with minimal additional design consideration in terms of coil overlap and geometry. Image quality was comparable to a commercially available RF coil.

MR systems for image-guided therapy.

The use of MRI to guide and monitor interventional procedures requires the merging of surgical and MRI environments. The ideal magnet shape for homogeneity and efficiency is spherical, but this design provides no access. Opening the sphere to provide both patient and surgeon access suggests cylindrical or biplanar magnets. Cylindrical magnets have poor surgical access but provide good imaging capabilities, which can be used in conjunction with a neighboring but distinct surgical environment. Biplanar magnets provide more and better approaches to the patient, but generally with lower field strength. Vertical biplanar systems allows surgical approaches from above but reduce the access of support staff to the patient. A hybrid magnet design, which combines the benefits of both cylindrical and biplanar magnets, can provide increased access with simultaneous approach from two sides of the patient. Application-specific magnets can target a smaller region, leading to compact magnet designs that greatly expand access for both surgical intervention as well as patient support. As the field of interventional MRI matures, the suitability of each design to specific applications will be better understood, leading to more integrated system designs tailored to the needs of image-guided therapy.

Interactive MR-guided biopsy in an open-configuration MR imaging system.

PURPOSE: To describe new techniques for percutaneous biopsy with use of an open-configuration magnetic resonance (MR) imaging system with integrated frameless stereotaxic guidance tools. MATERIALS AND METHODS: In 28 patients, biopsy was performed in which the image plane was interactively controlled by the position of a hand-held probe attached to the biopsy needle. An icon integrated into the image was used to guide needle advancement in three planes orthogonal to the needle. In vitro measurements of spatial accuracy were also performed. RESULTS: Diagnostic tissue was retrieved in 25 of 28 patients. The system was most accurate near the isocenter with a maximum measured error of 3.1 mm within a sphere of radius 2.5 cm about the isocenter. CONCLUSION: MR-guided biopsy with a frameless stereotaxic technique is safe and accurate. Image feedback is near real time, and the procedure is interactive. These techniques may be used to perform MR-guided biopsies and to place probes for MR-guided therapies.

Improved ejection fraction and flow velocity estimates with use of view sharing and uniform repetition time excitation with fast cardiac techniques.

PURPOSE: To improve the accuracy of ventricular volume estimates and effective temporal resolution in fast cardiac acquisitions. MATERIALS AND METHODS: Data sets at intermediate temporal phases were generated by means of sharing of views from two temporally adjacent data sets. A simulated model was used, and studies with patients and volunteers were conducted. View sharing was implemented in both fast gradient-echo and fast phase-contrast cine acquisitions; breath holding was used when possible. RESULTS: Uniform repetition time (TR) radio-frequency (RF) excitation allowed a better assessment of the end-diastolic ventricular volume. In addition, view sharing provided a better estimate of end-systolic ventricular volume in cases in which rapid changes in volume occurred at or about the temporal boundary of the source images. View sharing also provided a much smoother representation of dynamic cardiac motion when viewed in a cine loop. CONCLUSION: View sharing and uniform TR RF excitation improve the accuracy of end-systolic and end-diastolic ventricular volume measurements by improving the effective temporal resolution.