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1.
Proc Natl Acad Sci U S A ; 121(17): e2307216121, 2024 Apr 23.
Article in English | MEDLINE | ID: mdl-38621126

ABSTRACT

Uncontrolled fires place considerable burdens on forest ecosystems, compromising our ability to meet conservation and restoration goals. A poor understanding of the impacts of fire on ecosystems and their biodiversity exacerbates this challenge, particularly in tropical regions where few studies have applied consistent analytical techniques to examine a broad range of ecological impacts over multiyear time frames. We compiled 16 y of data on ecosystem properties (17 variables) and biodiversity (21 variables) from a tropical peatland in Indonesia to assess fire impacts and infer the potential for recovery. Burned forest experienced altered structural and microclimatic conditions, resulting in a proliferation of nonforest vegetation and erosion of forest ecosystem properties and biodiversity. Compared to unburned forest, habitat structure, tree density, and canopy cover deteriorated by 58 to 98%, while declines in species diversity and abundance were most pronounced for trees, damselflies, and butterflies, particularly for forest specialist species. Tracking ecosystem property and biodiversity datasets over time revealed most to be sensitive to recurrent high-intensity fires within the wider landscape. These megafires immediately compromised water quality and tree reproductive phenology, crashing commercially valuable fish populations within 3 mo and driving a gradual decline in threatened vertebrates over 9 mo. Burned forest remained structurally compromised long after a burn event, but vegetation showed some signs of recovery over a 12-y period. Our findings demonstrate that, if left uncontrolled, fire may be a pervasive threat to the ecological functioning of tropical forests, underscoring the importance of fire prevention and long-term restoration efforts, as exemplified in Indonesia.


Subject(s)
Butterflies , Fires , Animals , Ecosystem , Soil , Forests , Trees , Biodiversity
2.
Urogynecology (Phila) ; 30(2): 123-131, 2024 02 01.
Article in English | MEDLINE | ID: mdl-37428882

ABSTRACT

IMPORTANCE: Physical health and psychological health represent modifiable factors in the causal pathway of lower urinary tract symptoms (LUTS). OBJECTIVES: Understand the relationship between physical and psychological factors and LUTS over time. STUDY DESIGN: Adult women enrolled in the Symptoms of Lower Urinary Tract Dysfunction Research Network observational cohort study completed the LUTS Tool and Pelvic Floor Distress Inventory, including urinary (Urinary Distress Inventory), prolapse (Pelvic Organ Prolapse Distress Inventory), and colorectal anal (Colorectal-Anal Distress Inventory) subscales at baseline, 3 months, and 12 months. Physical functioning, depression, and sleep disturbance were measured using the Patient-Reported Outcomes Measurement Information System (PROMIS) questionnaires; relationships were assessed using multivariable linear mixed models. RESULTS: Of 545 women enrolled, 472 had follow-up. Median age was 57 years; 61% and 78% reported stress urinary incontinence and overactive bladder, respectively; and 81% reported obstructive symptoms. The PROMIS depression scores were positively associated with all urinary outcomes (range, 2.5- to 4.8-unit increase per 10-unit increase in depression score; P < 0.01 for all). Higher sleep disturbance scores were associated with higher urgency, obstruction, LUTS Total Severity, Urinary Distress Inventory, and Pelvic Floor Distress Inventory (1.9- to 3.4-point increase per 10-unit increase, all P < 0.02). Better physical functioning was associated with less severe urinary symptoms except stress urinary incontinence (2.3- to 5.2-point decrease per 10-unit increase, all P < 0.01). All symptoms decreased over time; however, no association was detected between baseline PROMIS scores and trajectories of LUTS over time. CONCLUSIONS: Nonurologic factors demonstrated small to medium cross-sectional associations with urinary symptom domains, but no significant association was detected with changes in LUTS. Further work is needed to determine whether interventions targeting nonurologic factors reduce LUTS in women.


Subject(s)
Colorectal Neoplasms , Lower Urinary Tract Symptoms , Urinary Incontinence, Stress , Urinary Tract , Adult , Humans , Female , Middle Aged , Cross-Sectional Studies
3.
J Pediatr Surg ; 59(1): 124-128, 2024 Jan.
Article in English | MEDLINE | ID: mdl-37802758

ABSTRACT

PURPOSE: Various techniques for neovaginal construction have been employed in the pediatric and adult populations, including the use of intestinal segments, buccal mucosal grafts, and skin grafts. Small intestinal submucosa (SIS) extracellular matrix grafts have been described as a viable alternative, though prior experience is limited. Our purpose was to assess operative characteristics and patient outcomes with neovaginal construction using SIS grafts. METHODS: Thirteen patients underwent vaginoplasty with acellular porcine SIS grafts at our institution between 2018 and 2022. Operative and clinical data, postoperative mold management, vaginal dilating length, and complications were reviewed. RESULTS: Age at time of repair ranged from 13 to 30 years (median 19 years). Patient diagnosis included cloacal anomalies (n = 4), Mayer-Rokitansky-Küster-Hauser syndrome (n = 4), isolated vaginal atresia with or without a transverse vaginal septum (n = 4), and vaginal rhabdomyosarcoma requiring partial vaginectomy (n = 1). Following dissection of the neovaginal space, a silicon mold wrapped with SIS graft was placed with retention sutures and removed on postoperative day 7. Median (IQR) operative time was 171 (118-192) minutes, estimated blood loss was 10 (5-20) mL, and length of stay was 2 (1-3) days. The follow-up period ranged from 3 to 47 months (median 9 months). Two patients developed postoperative vaginal stenosis that resolved with dilation under anesthesia. Mean vaginal length on latest follow-up was 8.97 cm. All thirteen patients had successful engraftment and progressed to performing self-dilations or initiating intercourse to maintain patency. There were no cases of graft reaction or graft extrusion. CONCLUSIONS: We conclude that acellular small intestinal submucosa grafts are effective and safe alternatives for mold coverage in neovaginal construction. Our experience demonstrates minimal perioperative morbidity, early mold removal, and progression to successful dilation with maintenance of a functional vaginal length. Future study on sexual outcomes, patient satisfaction, and comparison against alternative techniques has been initiated. LEVEL OF EVIDENCE: IV. TYPE OF STUDY: Retrospective Study.


Subject(s)
46, XX Disorders of Sex Development , Congenital Abnormalities , Plastic Surgery Procedures , Adult , Humans , Animals , Swine , Female , Child , Adolescent , Young Adult , Vagina/surgery , Vagina/abnormalities , Retrospective Studies , Constriction, Pathologic/surgery , Patient Satisfaction , Mullerian Ducts/surgery , Mullerian Ducts/abnormalities , 46, XX Disorders of Sex Development/surgery , Congenital Abnormalities/surgery , Treatment Outcome
4.
Int Urogynecol J ; 35(1): 31-34, 2024 Jan.
Article in English | MEDLINE | ID: mdl-38117297

ABSTRACT

This article explores the current landscape of clinical education in obstetrics and gynecology for medical students, residents, and fellows who identify as male. Academic, clinical instruction should be inclusive for the betterment of the training experience for all, but most importantly, for the betterment of women's health.


Subject(s)
Gynecology , Internship and Residency , Obstetrics , Female , Male , Humans , Gynecology/education , Obstetrics/education , Women's Health
5.
Behav Ecol ; 34(3): 418-425, 2023.
Article in English | MEDLINE | ID: mdl-37192927

ABSTRACT

Obtaining nesting material presents an optimal foraging problem, collection of materials incurs a cost in terms of risk of predation and energy spent and individuals must balance these costs with the benefits of using that material in the nest. The hazel dormouse, Muscardinus avellanarius is an endangered British mammal in which both sexes build nests. However, whether material used in their construction follows the predictions of optimal foraging theory is unknown. Here, we analyze the use of nesting materials in forty two breeding nests from six locations in Southwest England. Nests were characterized in terms of which plants were used, the relative amount of each plant, and how far away the nearest source was. We found that dormice exhibit a preference for plants closer to the nest, but that the distance they are prepared to travel depends on the plant species. Dormice traveled further to collect honeysuckle Lonicera periclymenum, oak Quercus robur, and beech Fagus sylvatica than any other plants. Distance did not affect the relative amount used, although the proportion of honeysuckle in nests was highest, and more effort was expended collecting honeysuckle, beech, bramble Rubus fruticosus and oak compared to other plants. Our results suggest that not all aspects of optimal foraging theory apply to nest material collection. However, optimal foraging theory is a useful model to examine nest material collection, providing testable predictions. As found previously honeysuckle is important as a nesting material and its presence should be taken account when assessing suitability of sites for dormice.

6.
South Med J ; 115(3): 187-191, 2022 03.
Article in English | MEDLINE | ID: mdl-35237836

ABSTRACT

OBJECTIVES: To compare urethral length (UL), as measured by three-dimenstional transvaginal ultrasound, before and after minimally invasive sacrocolpopexy (SCP). METHODS: Secondary analysis of a prospective cohort study of women undergoing SCP for prolapse beyond the hymen with or without a concomitant anti-incontinence procedure. Participants underwent ultrasound at baseline and 14 weeks postoperatively. UL was measured in a reconstructed sagittal plane from the bladder neck to the urethral meatus. All of the participants underwent multichannel urodynamics preoperatively. Data were analyzed in SPSS using independent or paired t tests as indicated for continuous variables and the McNemar test for paired dichotomous variables. Correlations including nonparametric data are reported as Spearman rho. RESULTS: A total of 28 participants, with a mean ± standard deviation age of 56 ± 10 years and median (interquartile range) preoperative prolapse stage of 3 (3-3), were analyzed. There was no change in UL between the baseline and 14-week visits (29.8 ± 11.0 mm vs 29.3 ± 10.0 mm, P = 0.83). There was no difference in baseline UL (29.4 ± 11.8 mm vs 30.9 ± 8.9 mm, P = 0.74) in those with and without preoperative stress urinary incontinence (SUI), nor was there a difference in baseline functional UL on multichannel urodynamics between these groups. In total, 21 participants (75%) had preoperative SUI and 19 (90%) underwent a concomitant anti-incontinence procedure. UL at 14 weeks was similar in those with and without SUI symptoms (26.5 ± 10.9 mm vs 31.1 ± 11.3 mm, P = 0.32) when controlling for those who underwent anti-incontinence procedures. CONCLUSION: UL does not change following suspension of the anterior vaginal wall with SCP.


Subject(s)
Pelvic Organ Prolapse , Aged , Female , Humans , Middle Aged , Pelvic Organ Prolapse/diagnostic imaging , Pelvic Organ Prolapse/surgery , Prospective Studies , Ultrasonography , Urodynamics , Vagina/diagnostic imaging , Vagina/surgery
7.
Female Pelvic Med Reconstr Surg ; 28(3): 173-176, 2022 03 01.
Article in English | MEDLINE | ID: mdl-35272325

ABSTRACT

OBJECTIVE: The objective of our study was to describe differences in commercial patient reviews of women and men urogynecologic surgeons. MATERIALS AND METHODS: Reviews of surgeons on Healthgrades.com in 4 metropolitan areas were included. Based on the qualitative assessment using qualitative content analysis of major and minor elements, we defined 4 theme categories: global experience, social interaction, technical skills, and ancillary aspects, each embedded with discrete elements. Differences in proportions of mentioned themes as well as quantitative ratings were evaluated by sex with the appropriate statistical tests. RESULTS: Three hundred sixty-four patient reviews (51% for women surgeons and 49% for men surgeons) were identified for 141 gynecologic surgeons self-identifying as "urogynecologists." The majority of the cohort (77%) held subspecialty certification in female pelvic medicine and reconstructive surgery. Reviews of women demonstrated a lower mean quantitative "likelihood to recommend" score compared with men (4.0 vs 4.3, P = 0.002) on the 5-point scale. Women received more mention in comfort (52% vs 40%, P = 0.023) and professionalism (19% vs 9%, P = 0.007) themes and less mention with respect to surgical outcomes (28% vs 53%, P < 0.001) and technical skills (5% vs 15%, P = 0.011) compared with men. CONCLUSIONS: Commercial online patient reviews for urogynecologic surgeons reveal sex bias with women receiving lower scores overall and more comments related to social interaction and fewer comments related to surgical outcomes and technical skill compared with men.


Subject(s)
Sex Characteristics , Surgeons , Clinical Competence , Female , Humans , Male , Patient Satisfaction , Sexism
8.
Behav Ecol ; 32(5): 1042-1053, 2021.
Article in English | MEDLINE | ID: mdl-34690550

ABSTRACT

Ambient noise can cause birds to adjust their songs to avoid masking. Most studies investigate responses to a single noise source (e.g., low-frequency traffic noise, or high-frequency insect noise). Here, we investigated the effects of both anthropogenic and insect noise on vocalizations of four common bird species in Hong Kong. Common Tailorbirds (Orthotomus sutorius) and Eurasian Tree Sparrows (Passer montanus) both sang at a higher frequency in urban areas compared to peri-urban areas. Red-whiskered Bulbuls (Pycnonotus jocosus) in urban areas shifted the only first note of their song upwards. Swinhoe's White-eye (Zosterops simplex) vocalization changes were correlated with noise level, but did not differ between the peri-urban and urban populations. Insect noise caused the Eurasian Tree Sparrow to reduce both maximum, peak frequency, and overall bandwidth of vocalizations. Insect noise also led to a reduction in maximum frequency in Red-whiskered bulbuls. The presence of both urban noise and insect noise affected the sound of the Common Tailorbirds and Eurasian Tree Sparrows; in urban areas, they no longer increased their minimum song frequency when insect sounds were also present. These results highlight the complexity of the soundscape in urban areas. The presence of both high- and low-frequency ambient noise may make it difficult for urban birds to avoid signal masking while still maintaining their fitness in noisy cities.

9.
Int Urogynecol J ; 32(8): 2011-2019, 2021 08.
Article in English | MEDLINE | ID: mdl-34191102

ABSTRACT

INTRODUCTION AND HYPOTHESIS: This segment of Chapter 1 of the International Urogynecology Consultation (IUC) on pelvic organ prolapse (POP) reviews the literature on the clinical definition of POP with the intent of creating standard terminology. METHODS: An international group containing nine urogynecologists and one university-based medical librarian performed a search of the literature using pre-specified search terms in PubMed, Embase, and Scopus. Publications were eliminated if not relevant to the clinical definition of POP, and those articles remaining were evaluated for quality using the Specialist Unit for Review Evidence (SURE). The resulting list of articles was used to inform a comprehensive review and creation of the clinical definition of POP. RESULTS: The original search yielded 31,931 references, of which 167 were used by the writing group. Ultimately, 78 are referenced in the manuscript. CONCLUSIONS: The clinical definition of POP for this review of the literature is: "anatomical prolapse with descent of at least one of the vaginal walls to or beyond the vaginal hymen with maximal Valsalva effort WITH the presence either of bothersome characteristic symptoms, most commonly the sensation of vaginal bulge, or of functional or medical compromise due to prolapse without symptom bother."


Subject(s)
Pelvic Organ Prolapse , Female , Humans , Referral and Consultation , Vagina
11.
Clin Obstet Gynecol ; 64(2): 297-305, 2021 06 01.
Article in English | MEDLINE | ID: mdl-33904837

ABSTRACT

The aim was to describe contemporary surgical procedures for the treatment of stress urinary incontinence (SUI) in women. The 4 most commonly performed surgical procedures for the treatment of SUI were reviewed using standardized terminology. We addressed the history and evolution of the procedures as well as the mechanisms of action by which they work. Efficacy and safety data were also presented. Midurethral Sling, Pubovaginal Sling, Retropubic Colposuspension, and Urethral Bulking are safe and effective procedures. Midurethral Sling, Pubovaginal Sling, Retropubic Colposuspension, and Urethral Bulking are contemporary procedures for the treatment of SUI in women.


Subject(s)
Suburethral Slings , Urinary Incontinence, Stress , Female , Humans , Urinary Incontinence, Stress/surgery , Urologic Surgical Procedures
12.
Female Pelvic Med Reconstr Surg ; 27(3): 170-174, 2021 03 01.
Article in English | MEDLINE | ID: mdl-33620900

ABSTRACT

OBJECTIVE: The objectives of this study were to describe patients' surgical goals and determine if goal attainment is associated with postoperative satisfaction and regret. METHODS: Women undergoing surgery for pelvic floor disorders between June and December 2019 were recruited. At their initial visit, patients listed up to 4 surgical goals. Three months after surgery, patients completed the Pelvic Floor Distress Inventory, Patient Global Impression of Improvement, Satisfaction with Decision Scale, and Decision Regret Scale. They were also shown their initial goals and asked, "Did you achieve this goal by having surgery?" Women who achieved all goals were designated "goal achievers," and those who did not achieve even 1 goal were "goal nonachievers" (GNAs). RESULTS: Ninety-nine patients listed a median of 1 (range, 1-4) goals. Goals were categorized as follows: symptom improvement (52%), treatment achievement (23%), lifestyle improvement (17%), and information gathering (6%). Ninety-one percent of patients were goal achievers, and 9% were GNAs. Goal achievers had higher Satisfaction with Decision Scale scores (5.0 [4.7-5.0] vs 4.0 [3.8-4.8], P = 0.002), lower Decision Regret Scale scores (1.0 [1.0-1.4] vs 2.0 [1.1-2.7], P = 0.001), and better Patient Global Impression of Improvement scores (1.0 [1.0-2.0] vs 2.0 [1.0-4.0], P = 0.004). In prolapse surgery patients, postoperative Pelvic Floor Distress Inventory scores were similar; however, GNAs had higher postoperative Urinary Distress Inventory scores (17.0 ± 18.0 vs 45.8 ± 20.8, P = 0.01). CONCLUSIONS: Ninety-one percent of women achieved their presurgical goals, the most common being symptom relief. Goal achievers have higher satisfaction and less regret; however, those with worsening or de novo urinary symptoms are more likely to be GNAs and be unsatisfied.


Subject(s)
Goals , Patient Satisfaction , Pelvic Floor Disorders/surgery , Adult , Aged , Emotions , Female , Humans , Middle Aged , Patient Reported Outcome Measures , Postoperative Complications/psychology , Retrospective Studies
13.
Female Pelvic Med Reconstr Surg ; 27(1): e184-e186, 2021 01 01.
Article in English | MEDLINE | ID: mdl-32412971

ABSTRACT

OBJECTIVE: The aim of the study was to compare levator hiatus (LH) and levator area (LA) on transvaginal 3-dimensional (3D) ultrasound (US) and genital hiatus (GH) size by Pelvic Organ Prolapse Quantification (POP-Q) examination before and after minimally invasive sacrocolpopexy. METHODS: Women with prolapse (POP) beyond the hymen undergoing minimally invasive sacrocolpopexy without concomitant POP repairs completed Pelvic Floor Distress Inventory short form (PFDI), POP-Q, and transvaginal 3D US before and 14 weeks after surgery. Data were analyzed by 2 urogynecologists, blinded to US image sequence and to corresponding POP-Q scores. RESULTS: Forty-three patients were enrolled; 35 with complete data are included. Patients had a mean ± SD age of 55 ± 11 years. Most were white (89%), vaginally parous (94%), postmenopausal (66%), sexually active (63%), and had stage 3 POP (86%). The majority (89%) had concomitant hysterectomy, and 60% had midurethral slings. At baseline, the mean ± SD PFDI and Prolapse subscale of the Pelvic Floor Distress Inventory scores were 98 ± 50 and 42 ± 22. The median (interquartile range) POP-Q stage decreased after surgery from 3 (3) to 0 (0-1, P < 0.001) and the mean ± SD PFDI scores decreased to 55 ± 42 (P = 0.002). At baseline, the mean ± SD GH and perineal body measurements were 3.5 ± 0.7 and 2.4 ± 0.6 cm. Although the GH size decreased by 0.5 cm after surgery, perineal body was unchanged. Levator hiatus remained unchanged between the baseline and 14-week visits (P = 0.07), whereas LA increased by 0.8 cm2 (P = 0.03). At 14 weeks, the change in LA was not correlated with the change in GH (ρ = -0.2, P = 0.2) or POP stage (ρ = -0.2, P = 0.9). CONCLUSIONS: Restoring the apex with sacrocolpopexy alone reduces GH size on clinical examination; however, it does not impact the size of the underlying LH on US.


Subject(s)
Muscle, Striated/anatomy & histology , Pelvic Organ Prolapse/surgery , Adult , Aged , Female , Gynecologic Surgical Procedures/methods , Humans , Middle Aged , Organ Size , Pelvis , Postoperative Period , Prospective Studies , Sacrum/surgery , Vagina/surgery
14.
Female Pelvic Med Reconstr Surg ; 27(1): e118-e121, 2021 01 01.
Article in English | MEDLINE | ID: mdl-32487882

ABSTRACT

OBJECTIVE: The aim of the study was to describe the rate of symptomatic and asymptomatic urinary retention and catheterization in women undergoing initial intravesical onabotulinumtoxinA (BnTA) injection for urgency urinary incontinence (UUI). METHODS: This retrospective chart review included women receiving initial 100 U of BnTA injection for UUI for 5 years. Straight-catheterized postvoid residuals (PVRs) were performed 2 weeks after the injection. Women without the sensation of incomplete bladder emptying, worsened urgency, inability to void, or suprapubic pain but with PVR of greater than 300 mL were characterized as having asymptomatic retention, whereas women with a PVR of greater than 150 and any of these symptoms were diagnosed with symptomatic retention. RESULTS: One hundred eighty-seven 187 patients received initial BnTA injection. The majority were postmenopausal (89%) and white (82%) with a mean age of 65 years and body mass index of 30 kg/m2. One-third of the cohort underwent baseline urodynamic studies. At 2 weeks after injection, 163 patients (87%) followed up, and 17 (10%) had either asymptomatic or symptomatic retention (2% and 8%, respectively). There were no differences in demographic or pretreatment urodynamic parameters in women with and without retention except that women who had previous anti-stress urinary incontinence procedures were more likely to experience retention (53% vs 18%, P = 0.002) despite similar baseline PVRs. CONCLUSION: We demonstrated that the rate of retention requiring catheterization after 100 U BnTA may be as high as 10% although only 5% develop PVRs for 300 mL and only 2% have asymptomatic retention for 300 mL.


Subject(s)
Botulinum Toxins, Type A/administration & dosage , Urinary Incontinence, Urge/drug therapy , Administration, Intravesical , Aged , Botulinum Toxins, Type A/adverse effects , Female , Humans , Middle Aged , Retrospective Studies , Urinary Retention/chemically induced
15.
Female Pelvic Med Reconstr Surg ; 27(6): 356-359, 2021 06 01.
Article in English | MEDLINE | ID: mdl-32487885

ABSTRACT

OBJECTIVE: The aim of the study was to compare narcotic requirements with early postoperative pain scores in women undergoing apical prolapse surgery with or without hysterectomy. METHODS: All cases of apical prolapse repair at our institution in 2016 were identified. The following was abstracted from the health record: demographics, comorbidities, procedure details, baseline and postoperative care unit (PACU) pain scores, and operating room (OR) and PACU narcotic doses. Doses were converted to morphine milligram equivalents (MME) for analysis. Correlations are reported using Pearson ρ. RESULTS: One hundred fifty-six cases were identified. Seventy-eight percent of participants were white and the mean ± SD age was 59 ± 11 years. One hundred seventeen patients (75%) underwent laparoscopic/robotic sacrocolpopexy, 35 (22%) native tissue vaginal repairs, and 4 (3%) open sacrocolpopexy. One hundred twenty-two patients (78%) underwent concomitant hysterectomy: 93 (76%) were laparoscopic, 25 (20%) vaginal, and 4 (4%) abdominal.The groups were similar, with the exception of younger age and longer OR time in the hysterectomy group. Hysterectomy by any route was not associated with increased OR MMEs (29 vs 22, P = 0.22), PACU MMEs (13 vs 13, P = 0.54), 4-hour PACU pain scores (2.5 vs 2.0, P = 0.22), or 6-hour PACU pain scores (2.6 vs 2.3, P = 0.54). After controlling for age and OR time, there remained no differences in these variables. Likewise, when analyzing laparoscopic or vaginal groups separately on multivariate regression, there were no differences in MMEs or postoperative pain scores in patients with and without concomitant hysterectomy. CONCLUSIONS: Concomitant hysterectomy at the time of prolapse repair does not increase pain medication requirements or patient-reported postoperative pain scores.


Subject(s)
Hysterectomy/adverse effects , Narcotics/therapeutic use , Pain Measurement , Pain, Postoperative/drug therapy , Pain, Postoperative/etiology , Pelvic Organ Prolapse/surgery , Aged , Female , Gynecologic Surgical Procedures/methods , Humans , Middle Aged , Retrospective Studies
16.
Female Pelvic Med Reconstr Surg ; 27(6): e559-e562, 2021 06 01.
Article in English | MEDLINE | ID: mdl-33315624

ABSTRACT

OBJECTIVE: The aim of this study was to describe trends in sling procedures and revisions, including fascial slings and midurethral slings (MUS) using a large, national database with respect to the 2011 U.S. Food and Drug Administration (FDA) mesh-related safety communication. METHODS: This was a cross-sectional cohort study using data from the American College of Surgeons National Surgical Quality Improvement Program (ACS NSQIP) database from 2010 to 2018, evaluating the prevalence of sling revision and fascial slings and their trends over time. Patients who underwent MUS, fascial slings, and sling revisions were identified by Current Procedural Terminology codes. Sling revisions and fascial slings were evaluated as a proportion of the total number of MUS performed per year. Three distinct periods were evaluated in relation to the 2011 FDA communication: 2010 to 2012, 2012 to 2015, and 2015 to 2018. Observed trends were assessed with Pearson correlation coefficients with a P value less than 0.05 considered significant. RESULTS: During the study period, 32,657 slings were captured: 32,389 MUS and 268 fascial slings. The rate of sling revisions was low (0.4% in 2010 to 1.2% in 2015). Between 2012 and 2015, the rate of sling revision increased significantly (R = 1, P = 0.002); following 2015, the rate of sling revisions decreased significantly over time (R = -0.96, P = 0.04). The rate of fascial slings between 2012 and 2015 increased significantly (R = 0.95, P = 0.047); however, the rate plateaued starting in 2015 (R = -0.49, -P = 0.51). CONCLUSIONS: Our data suggest that MUS remain the preferred procedure for treatment of stress urinary incontinence despite the recent FDA communications with MUS representing 99% of sling procedures during the study period.


Subject(s)
Quality Improvement , Reoperation/statistics & numerical data , Suburethral Slings/statistics & numerical data , Urethra/surgery , Urinary Incontinence, Stress/surgery , Urologic Surgical Procedures/statistics & numerical data , Adult , Aged , Cohort Studies , Cross-Sectional Studies , Female , Humans , Middle Aged , Pain, Postoperative , Postoperative Complications , Suburethral Slings/adverse effects , Treatment Outcome , Urinary Incontinence, Stress/epidemiology , Urologic Surgical Procedures/methods
17.
Female Pelvic Med Reconstr Surg ; 27(2): e336-e341, 2021 02 01.
Article in English | MEDLINE | ID: mdl-32947549

ABSTRACT

OBJECTIVE: To assess the relationship between postoperative activity recommendations and satisfaction and anatomic and functional outcomes 1 year after surgery for symptomatic prolapse. METHODS: This is a planned secondary analysis reporting 1-year functional and anatomic outcomes of a multicenter, randomized, double-masked clinical trial "ReCOUP." In the original trial, women undergoing surgery for prolapse were randomized to liberal (no limitations on physical activity) or restricted (heavy lifting and high-impact activity prohibited) postoperative activity recommendations for 3 months after surgery. At 1 year, our primary outcome was satisfaction, assessed using a 5-point Likert scale answer to the question, "How satisfied are you with the result of your prolapse surgery?" Anatomic surgical failure was met if women had prolapse beyond the hymen, apical descent greater than one third the vaginal length, OR retreatment for prolapse. RESULTS: Of the 95 women (n = 45 liberal, n = 50 restricted) who were randomized and completed primary 3-month outcomes, 83 (87%) completed a functional assessment, and 77 (81%) completed both functional and anatomic assessment at 1 year. Satisfaction with surgery remained high (91.5%) with no differences between groups (86.8% vs 95.6% P = 0.155) as did anatomic and functional outcomes. There were 7.8% women who met criteria for anatomic surgical failure with no difference between the restricted (7.0%) and liberal group (8.8%). Three women (2 in the restricted group, 1 in the liberal group) with recurrent prolapse and underwent surgery. CONCLUSIONS: There were no significant differences in anatomic and functional outcomes at 12 months after surgery in women who resume postoperative activity liberally and those who restrict postoperative activity.


Subject(s)
Convalescence , Exercise , Gynecologic Surgical Procedures , Patient Satisfaction/statistics & numerical data , Pelvic Organ Prolapse/surgery , Postoperative Care/methods , Urologic Surgical Procedures , Adult , Aged , Aged, 80 and over , Double-Blind Method , Female , Follow-Up Studies , Humans , Middle Aged , Recovery of Function , Treatment Outcome
18.
Female Pelvic Med Reconstr Surg ; 27(2): e333-e335, 2021 02 01.
Article in English | MEDLINE | ID: mdl-33002897

ABSTRACT

OBJECTIVE: To describe surgical technique and outcomes of early secondary repair of obstetric anal sphincter injury (OASIS) breakdown. METHODS: This was a case series of all women presenting to a subspecialty peripartum clinic within 2 months of an OASIS, who ultimately underwent secondary surgical repair between September 2013 and January 2018. Cases were identified using the following CPT codes: 57308 (transperineal fistula repair), 56910 (repair of the perineum), and 46750 (repair of anal sphincter). Four board-certified urogynecologists performed all surgical procedures using the same technique: demographics, delivery data, and preoperative and postoperative data were collected. RESULTS: Eighteen women were identified. The majority (16 [88.9%] of 18) were primiparous; 9 (50%) women underwent spontaneous vaginal delivery and 9 (50%) women underwent forceps-assisted vaginal delivery. Over 70% (13 [72.2%] of 18) suffered a 3rd-degree tear, whereas 5 (27.8%) of 18 had a 4th-degree laceration. The median time after delivery to specialty clinic presentation was 10 days (interquartile range, 5.3-52.5 days). All women were diagnosed with wound breakdown at their initial visit. Seven (38.9%) also had a concomitant rectovaginal fistula.Median time from diagnosis of wound breakdown to secondary operative revision was 19.5 days (interquartile range, 12-26.8 days). Seventeen (94.4%) of the 18 women underwent overlapping external anal sphincteroplasty with perineorrhaphy; of these, 7 (41.2%) also underwent concurrent repair of their rectovaginal fistula. One woman underwent perineorrhaphy alone. At 3 months postoperatively, no women had a wound breakdown or recurrent fistula. CONCLUSIONS: In women with OASIS breakdown, early secondary repair is both feasible and successful with meticulous surgical technique.


Subject(s)
Anal Canal/injuries , Gynecologic Surgical Procedures/methods , Lacerations/surgery , Obstetric Labor Complications/surgery , Reoperation/methods , Adult , Anal Canal/surgery , Female , Humans , Lacerations/etiology , Postoperative Complications/surgery , Pregnancy , Retrospective Studies , Time-to-Treatment , Treatment Outcome , Wound Healing
19.
Female Pelvic Med Reconstr Surg ; 27(2): e309-e314, 2021 02 01.
Article in English | MEDLINE | ID: mdl-33009264

ABSTRACT

OBJECTIVES: The objective of this study was to determine whether a computerized, condition-specific Decision Analysis Tool (DAT) for the surgical treatment of pelvic organ prolapse (POP) improves patient satisfaction and alters decision making. METHODS: Together with a health care startup company, we created a computerized DAT using the best evidence available on success rates and risks associated with sacrocolpopexy, native tissue apical suspension, and colpocleisis. Consecutively scheduled women before and after implementation of the DAT in an academic practice of 4 fellowship-trained, board-certified urogynecologists were included. The primary outcome was patient satisfaction using the Satisfaction with Decision Scale (SDS). Secondary outcomes included the Decision Regret Scale (DRS) questionnaire, differences in surgical choice, patient-reported outcomes, and individual SDS and DRS items. The SDS and DRS were administered at the 3-month postoperative visit. RESULTS: Forty-seven women before DAT implementation and 54 women after DAT implementation were included. There were no differences in SDS or DRS total scores (4.62 ± 0.66 vs 4.52 ± 0.72, P = 0.10 and 1.48 ± 0.79 vs 1.52 ± 0.82, P = 0.77) or individual question responses between groups. Women using the DAT were more likely to choose sacrocolpopexy than those who did not (76% vs 51%, P = 0.01). All 3 procedures led to similarly improved POP symptoms (P = 0.98), but those who underwent sacrocolpopexy had higher SDS scores compared with native tissue or colpocleisis patients (P = 0.01). Several individual SDS and DRS items were more favorable after sacrocolpopexy. CONCLUSIONS: Women choosing surgery for POP are satisfied with their decision-making experiences with and without the assistance of a DAT. More women using a DAT, however, undergo sacrocolpopexy, which is associated with improved satisfaction.


Subject(s)
Clinical Decision-Making/methods , Decision Support Systems, Clinical , Gynecologic Surgical Procedures/methods , Patient Participation/methods , Patient Satisfaction/statistics & numerical data , Pelvic Organ Prolapse/surgery , Adult , Aged , Aged, 80 and over , Female , Humans , Linear Models , Logistic Models , Middle Aged , Prospective Studies , Treatment Outcome
20.
Female Pelvic Med Reconstr Surg ; 26(5): 299-305, 2020 05.
Article in English | MEDLINE | ID: mdl-32324683

ABSTRACT

Although the peak incidence of surgery for pelvic floor disorders does not occur until after menopause, an increasing number of younger women are seeking treatment for these problems. Whereas most surgeons would recommend delaying surgery until the completion of childbearing, published cases and case series address outcomes after subsequent pregnancies in women who have been treated for urinary incontinence and pelvic organ prolapse. This document synthesizes the available evidence on the impact of pregnancy on women with prior treatment for pelvic floor disorders and on the impact of these prior treatments on subsequent pregnancy. Pregnancy after the repair of obstetrical anal sphincter laceration is also discussed. Consensus recommendations are presented based on available literature review and expert involvement.


Subject(s)
Pelvic Floor Disorders/surgery , Plastic Surgery Procedures/adverse effects , Pregnancy Complications/etiology , Delivery, Obstetric/adverse effects , Female , Humans , Pelvic Floor Disorders/complications , Pregnancy , Recurrence , Risk Factors , Suburethral Slings/adverse effects
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