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Int J Cardiol ; 144(2): 302-3, 2010 Oct 08.
Article in English | MEDLINE | ID: mdl-19329199

ABSTRACT

Beta blockers are contraindicated in patients with acutely decompensated heart failure. Current therapeutic strategies increase morbidity and mortality. We have compared the effects of frequent doses of diuretics vs a single dose of diuretics and cautious uptitration of carvedilol. Our results indicate that, although clinical compensation is achieved with both strategies; the effects on neurohormonal activation and ventricular arrhythmias are opposite.


Subject(s)
Adrenergic beta-Antagonists/administration & dosage , Carbazoles/administration & dosage , Diuretics/administration & dosage , Furosemide/administration & dosage , Heart Failure/drug therapy , Propanolamines/administration & dosage , Acute Disease , Adrenergic beta-Antagonists/pharmacology , Carvedilol , Diuretics/pharmacology , Drug Administration Schedule , Drug Therapy, Combination , Furosemide/pharmacology , Humans , Sympathetic Nervous System/drug effects , Systole , Tachycardia, Ventricular/chemically induced
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