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1.
Rev Sci Instrum ; 90(11): 115114, 2019 Nov 01.
Article in English | MEDLINE | ID: mdl-31779406

ABSTRACT

We report on the design, construction, and performance of a compact magnetic shield that facilitates a controlled, low-noise environment for experiments with ultracold atomic gases. The shield was designed to passively attenuate external slowly varying magnetic fields while allowing for ample optical access. The geometry, number of layers, and choice of materials were optimized using extensive finite-element numerical simulations. The measured performance of the shield is in good agreement with the simulations. From measurements of the spin coherence of an ultracold atomic ensemble, we demonstrate a residual field noise of 2.6 µG and a suppression of external dc magnetic fields by more than five orders of magnitude.

2.
J Endocrinol Invest ; 17(3): 171-9, 1994 Mar.
Article in English | MEDLINE | ID: mdl-8051339

ABSTRACT

Very Low Calorie Diet (VLCD) is known to induce not only weight loss, but also an improvement of metabolic control, in obese type II diabetics. In order to evaluate the therapeutical efficacy of cycles of VLCD shorter than those previously described, 29 obese type II diabetics and 31 obese nondiabetic subjects were entered as inpatients and prescribed a 450 kcal/day diet for 15 days. Metabolic results obtained were similar to those achieved with longer cycles of VLCD, showing that 15 days are sufficient to induce a BMI decrease in diabetic (BMI from 35.3 +/- 4.8 to 33.3 +/- 4.6 after VLCD) and nondiabetic patients (BMI from 40.5 +/- 7.4 to 38.1 +/- 7.2 after VLCD), a desired fall of blood glucose levels and the decrease of daily insulin needs in insulin-treated patients. Glucagon tests were performed before and after VLCD in order to study possible modifications of insulin secretion. Although we did not observe any significant increase of C-peptide basal or peak levels (nM/ml) either in diabetic (basal levels before VLDC: 1.2 +/- 0.4 and peak levels 2.4 +/- 0.7; basal after VLCD 1.23 +/- 0.6 and peak 2.6 +/- 0.7) and nondiabetic patients (basal levels before VLDC 1.0 +/- 0.3 and peak levels 2.5 +/- 0.4; basal after VLCD 0.9 +/- 0.3 and peak 2.4 +/- 0.6). The rise of the C-peptide/glycemia ratio is an index of an improvement of insulin biological activity, which could be partly responsible for the therapeutical effects of VLCD.(ABSTRACT TRUNCATED AT 250 WORDS)


Subject(s)
Diabetes Mellitus, Type 2/diet therapy , Diabetes Mellitus/diet therapy , Diet, Reducing , Obesity , Adult , Blood Glucose/metabolism , C-Peptide/blood , Diabetes Mellitus/metabolism , Diabetes Mellitus, Type 2/metabolism , Energy Intake , Female , Glucagon , Humans , Insulin/metabolism , Insulin Secretion , Male , Middle Aged , Receptor, Insulin/physiology , Weight Loss
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