Subject(s)
Diabetic Angiopathies/diagnosis , Diabetic Angiopathies/drug therapy , Diabetic Retinopathy/diagnosis , Diabetic Retinopathy/drug therapy , Insulin/therapeutic use , Acute Disease , Adolescent , Diabetes Mellitus/blood , Diabetes Mellitus/drug therapy , Female , Humans , Hyperglycemia/complications , Hyperglycemia/drug therapy , Remission InductionABSTRACT
La toxoplasmosis ocular es una enfermedad que puede tener graves consecuencias visuales. El objetivo es presentar un caso clínico de toxoplasmosis ocular bilateral severa en una paciente alérgica a sulfamidas en el que la reactivación monolateral de la enfermedad responde de forma favorable ante el tratamiento con clindamicina intravítrea y corticoterapia oral. Se muestra como la administración de clindamicina mediante inyecciones intravítreas semanales supone una alternativa terapéutica segura en aquellos casos de toxoplasmosis ocular severa y/o en los que existe contraindicación para el tratamiento clásico. La clindamicina intravítrea es una alternativa terapéutica segura con resultados clínicos favorables
Ocular toxoplasmosis is a disease than have severe consequences on the eyesight. The aim of this study article is to present a bilateral ocular toxoplasmosis in a sulfamide allergic patient with unilateral activation and her favourable progression with intravitreal Clindamycin and oral steroids treatment. Weekly intravitreal Clindamycin treatment is shown to be a suitable therapeutic alternative in cases of severe ocular toxoplasmosis and/or in patients with a contraindication to classical treatment. Intravitreal Clindamycin treatment is a safe alternative with favourable clinical results
Subject(s)
Humans , Female , Adult , Anti-Bacterial Agents/administration & dosage , Clindamycin/administration & dosage , Toxoplasmosis, Ocular/drug therapy , Fluorescein Angiography , Intravitreal Injections , Tomography, Optical Coherence , Toxoplasmosis, Ocular/diagnostic imagingABSTRACT
Ocular toxoplasmosis is a disease than have severe consequences on the eyesight. The aim of this study article is to present a bilateral ocular toxoplasmosis in a sulfamide allergic patient with unilateral activation and her favourable progression with intravitreal Clindamycin and oral steroids treatment. Weekly intravitreal Clindamycin treatment is shown to be a suitable therapeutic alternative in cases of severe ocular toxoplasmosis and/or in patients with a contraindication to classical treatment. Intravitreal Clindamycin treatment is a safe alternative with favourable clinical results.
Subject(s)
Anti-Bacterial Agents/administration & dosage , Clindamycin/administration & dosage , Toxoplasmosis, Ocular/drug therapy , Adult , Female , Fluorescein Angiography , Humans , Intravitreal Injections , Tomography, Optical Coherence , Toxoplasmosis, Ocular/diagnostic imagingABSTRACT
No disponible
Subject(s)
Humans , Female , Young Adult , Air Bags/adverse effects , Choroid/injuries , Eye Injuries/etiology , Rupture/etiology , Wounds, Nonpenetrating/etiology , Choroid/diagnostic imagingABSTRACT
No disponible
Subject(s)
Humans , Male , Middle Aged , Chorioretinitis/etiology , Acute Disease , Anti-Bacterial Agents/therapeutic use , Chorioretinitis/drug therapy , Ophthalmoscopy , Penicillin G/therapeutic use , Retinal Pigments , Epithelium/pathology , Scotoma/etiology , Syphilis/diagnosis , Syphilis/drug therapySubject(s)
Chorioretinitis/etiology , Syphilis/complications , Acute Disease , Anti-Bacterial Agents/therapeutic use , Chorioretinitis/drug therapy , Humans , Male , Middle Aged , Ophthalmoscopy , Penicillin G/therapeutic use , Retinal Pigment Epithelium/pathology , Scotoma/etiology , Syphilis/diagnosis , Syphilis/drug therapyABSTRACT
CASE REPORT: Ocular examinations and optical coherence tomography (OCT) were performed in three patients with retinal phototoxicity lesions. Fluorescein angiography depicted a window defect. OCT exhibited hyporeflectivity at the outer foveal retina and fragmentation of the inner reflective layers, corresponding to the junction between the inner and outer photoreceptor segments. DISCUSSION: Retinal damage after light exposure has a rapid onset and shows different patterns in OCT examination. OCT findings suggest that decreased visual acuity may be associated with full-thickness photoreceptors and retinal pigment epithelium (RPE) involvement. OCT is a useful tool for objective assessment of retinal pathology in phototoxicity cases where fundus changes may be minimal or absent.
Subject(s)
Light/adverse effects , Macula Lutea , Retinal Diseases/diagnosis , Retinal Diseases/etiology , Tomography, Optical Coherence , Adult , Female , Humans , Male , Middle Aged , Retina/injuries , Retina/pathologyABSTRACT
Caso clínico: Se realiza una exploración ocular y tomografía de coherencia óptica (OCT) en tres pacientes con lesiones fototóxicas retinianas. Las angiografías fluoresceínicas muestran un defecto ventana. La OCT muestra hiporreflectividad en la porción externa de la fóvea y fragmentación de las capas más internas entre la porción interna de los fotorreceptores y los segmentos externos. Discusión: Las lesiones retinianas tras exposición a la luz aparecen precozmente mostrando diferentes patrones en la OCT. La OCT sugiere que la disminución de visión asocia una lesión de fotorreceptores y epitelio pigmentario retiniano (EPR). La OCT es útil para objetivar la retinopatía fototóxica donde los cambios oftalmoscópicos pueden estar ausentes o ser mínimos
Case report: Ocular examinations and optical coherence tomography (OCT) were performed in three patients with retinal phototoxicity lesions. Fluorescein angiography depicted a window defect. OCT exhibited hyporeflectivity at the outer foveal retina and fragmentation of the inner reflective layers, corresponding to the junction between the inner and outer photoreceptor segments. Discussion: Retinal damage after light exposure has a rapid onset and shows different patterns in OCT examination. OCT findings suggest that decreased visual acuity may be associated with full-thickness photoreceptors and retinal pigment epithelium (RPE) involvement. OCT is a useful tool for objective assessment of retinal pathology in phototoxicity cases where fundus changes may be minimal or absent (Arch Soc Esp Oftalmol 2008; 83: 267-272)
