ABSTRACT
The antimicrobial activity of Vismia macrophylla extract is reported in the literature; however, little is known about the presence of phenolic compounds and their antimicrobial activity in this species. This study aimed to isolate phenolic compounds with antimicrobial action from the leaves of V. macrophylla. The ethanolic extract (VmL-Et) was submitted to sephadex column separation, and some fractions were submitted to derivatization with BSTFA and analysed by GC-MS. This study indicated the presence of the catechin, osajaxanthone, quercetin, quercitrin, and glucodistylin. Of these, osajaxanthone, quercetin, quercitrin, and glucodistylin were isolated and identified by spectroscopic techniques. VmL-Et, quercetin, quercitrin, glucodistylin, and maslinic acid, were tested against the Acinetobacter baumannii, Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus and Enterococcus faecalis. The results showed broad spectrum action of the extract Vm-Et, glucodistylin and quercitrin. The species V. macrophylla occurring in the Brazilian biome showed potential for obtaining phenolic compounds that can help combat microbial resistance.
ABSTRACT
Resumo Estudo exploratório de abordagem qualitativa que buscou analisar os conhecimentos, percepções e práticas de equipes de Saúde Bucal e de agentes comunitários de saúde acerca das políticas públicas que regulamentam a utilização de plantas medicinais e fitoterápicos no contexto das práticas integrativas e complementares, incluindo sua incorporação, reconhecimento, desafios e possibilidades no cotidiano local do SUS. Foram selecionadas oito Unidades Básicas de Saúde no município de Itabuna, Bahia, Brasil, com a realização de entrevistas com oito cirurgiões-dentistas, oito auxiliares/técnicos de saúde bucal e oito agentes comunitários de saúde, totalizando 24 participantes. Para a análise da dados, empregou-se a técnica do Discurso do Sujeito Coletivo. Os conhecimentos, percepções e práticas dos atores envolvidos no estudo sobre as políticas públicas de inserção das plantas medicinais no SUS mostraram-se permeados pela cultura hegemônica, pela formação em saúde tradicional e fragmentada, pelo (des)interesse administrativo do município e por subjetividades individuais que são produzidas e reproduzidas nos serviços de saúde bucal da APS local.
Abstract This exploratory and qualitative study aimed to analyze the knowledge, perceptions and practices of Oral Health Teams and Community Health Agents about public health policies that regulate the use of medicinal plants and herbal medicines in the context of integrative and complementary practices, including their incorporation, recognition, challenges and possibilities in the local routine of the Brazilian Unified Health System (SUS). Eight Basic Health Units were selected in the municipality of Itabuna, Bahia, Brazil, and interviews were conducted with 8 dentists, 8 oral health assistants/technicians and 8 community health agents, totaling 24 participants. For data analysis, the Collective Subject Discourse technique was used. The knowledge, perceptions and practices of the actors involved in the study about public policies for the introduction of medicinal plants in the SUS were permeated by the hegemonic culture, traditional and fragmented health education, the administrative (un)interest of the municipal authorities, and individual subjectivities that are produced and reproduced in the local oral health services and the primary care.
