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1.
Phys Rev E ; 96(3-1): 032121, 2017 Sep.
Article in English | MEDLINE | ID: mdl-29347039

ABSTRACT

The exact finite-size partition function for the nonhomogeneous one-dimensional (1D) Ising model is found through an approach using algebra operators. Specifically, in this paper we show that the partition function can be computed through a trace from a linear second-order recurrence relation with nonconstant coefficients in matrix form. A relation between the finite-size partition function and the generalized Lucas polynomials is found for the simple homogeneous model, thus establishing a recursive formula for the partition function. This is an important property and it might indicate the possible existence of recurrence relations in higher-dimensional Ising models. Moreover, assuming quenched disorder for the interactions within the model, the quenched averaged magnetic susceptibility displays a nontrivial behavior due to changes in the ferromagnetic concentration probability.

2.
Phys Rev Lett ; 106(11): 117002, 2011 Mar 18.
Article in English | MEDLINE | ID: mdl-21469890

ABSTRACT

We calculate the magnetic and quasiparticle excitation spectra of an itinerant J(1)-J(2) model for iron-pnictide superconductors. In addition to an acoustic spin-wave branch, the magnetic spectrum has a second, optical branch, resulting from the coupled four-sublattice magnetic structure. The spin-wave velocity has also a planar directional anisotropy, due to the collinear or striped antiferromagnetism. Within the magnetically ordered phase, the quasiparticle spectrum is composed of two Dirac cones, resulting from the folding of the magnetic Brillouin zone. We discuss the relevance of our findings to the understanding of both neutron scattering and photoemission spectroscopy results for SrFe(2)As(2).

3.
Phys Rev Lett ; 101(3): 037201, 2008 Jul 18.
Article in English | MEDLINE | ID: mdl-18764283

ABSTRACT

We present a mean-field solution for a quantum, short-range interacting, disordered, SO(3) Heisenberg spin model, in which the Gaussian distribution of couplings is centered in an antiferromagnetic (AF) coupling J[over ]>0, and which, for weak disorder, can be treated as a perturbation of the pure AF Heisenberg system. The phase diagram contains, apart from a Néel phase at T=0, spin-glass and paramagnetic phases whose thermodynamic stability is demonstrated by an analysis of the Hessian matrix of the free-energy. The magnetic susceptibilities exhibit the typical cusp of a spin-glass transition.

4.
Hum Gene Ther ; 11(15): 2079-91, 2000 Oct 10.
Article in English | MEDLINE | ID: mdl-11044910

ABSTRACT

Recombinant adeno-associated virus (AAV) holds much promise for human gene therapy. While evidence indicates that AAV mediates long-term gene transfer in several different tissues, difficulty in preparing and purifying this viral vector in large quantities remains a major obstacle for evaluating AAV vectors in clinical trials. The current method of purification, based on sedimentation through cesium chloride, is not scaleable and yields product of insufficient quality. In this article we report a new technique for purifying AAV, using a fully closed two-column chromatography system. Yields of AAV vectors purified by this method are high, potency is increased, and the purity of column-purified preparations is substantially improved. We previously reported a novel method to generate AAV based on an AAV Rep/Cap-containing cell line (B50) and an Ad-AAV hybrid virus, which is amenable to scale-up in bioreactors. By combining the new, fully scaleable purification process we report here with the B50/hybrid production method, it would be feasible to prepare AAV vectors to the scale and purity required for clinical and potential commercial applications.


Subject(s)
Chromatography, Ion Exchange/methods , Dependovirus/genetics , Dependovirus/isolation & purification , Genetic Therapy/methods , Genetic Vectors/isolation & purification , Animals , Bioreactors , Blotting, Western , Cell Line , Centrifugation, Density Gradient , Cytokines/metabolism , Dependovirus/ultrastructure , Electrophoresis, Polyacrylamide Gel , Gene Transfer Techniques , Humans , Mice , Mice, Inbred C57BL , Microscopy, Electron , Muscles/virology , Silver Staining , Tibia/virology , Time Factors , Transduction, Genetic , Transfection , Ultraviolet Rays
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