Subject(s)
Pancreaticojejunostomy/methods , Anesthesia, General , Animals , Cyanoacrylates/administration & dosage , Follow-Up Studies , Humans , Intubation , Models, Animal , Pancreatic Ducts , Pancreatic Fistula/etiology , Pancreatic Fistula/prevention & control , Proteins/administration & dosage , Swine , Time Factors , Tissue Adhesives/administration & dosage , Treatment OutcomeABSTRACT
Spontaneous spinal epidural haematomas are quite rare. We report here the case of a 27-year-old woman, without previous history of relevant medical disorder, who presented with acute paraplegia at 36 weeks of gestation. MRI performed in emergency revealed a T8 epidural haematoma. The management consisted in an emergency Caesarean section under general anaesthesia, followed immediately by a T8 laminectomy allowing the spinal cord decompression 14 hours after the first symptoms. Neurologic recovery was rapid and complete, except for bladder dysfunction persisting one month later. Spontaneous spinal epidural haematomas require a prompt diagnosis because neurologic prognosis essentially depends on the interval of time between onset of symptoms and surgical decompression. Obstetrical management especially depends on the term of pregnancy. For the anaesthesiologist, the difficulty is the management of both pregnant condition (full stomach general anaesthesia) and spinal cord compression (maintenance of spinal cord perfusion pression and limitation of ischaemia and oedema).
Subject(s)
Hematoma, Epidural, Spinal/surgery , Pregnancy Complications/surgery , Adult , Cesarean Section , Female , Hematoma, Epidural, Spinal/complications , Hematoma, Epidural, Spinal/pathology , Humans , Laminectomy , Paraplegia/etiology , Pregnancy , Pregnancy Complications/pathologyABSTRACT
Acute hepatic porphyrias are genetic diseases, characterized by acute neurological symptoms, sometimes fatal, triggered by different factors, in particular by many anaesthetic drugs, and also by pregnancy. We report here the experience of three porphyric patients'deliveries, allowing us to consider a proposition of management in this context. After discussion between anaesthesiologist, obstetrician and porphyria specialist, two types of management of such patients can be foresee. Asymptomatic patients, or in long remission, can benefit from locoregional anesthesia techniques with bupivacaine for both labour analgesia and Caesarean section. Spinal anaesthesia is then the technique of choice, allowing using smaller quantity of local anaesthetic than epidural anaesthesia. For symptomatic patients, or in crisis, we have rather choose intravenous narcotics for labour analgesia, and general anaesthesia for Caesarean section. The hypnotic agent of choice for both induction and maintenance of such anaesthesia is then propofol.
