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1.
BMJ Case Rep ; 14(8)2021 Aug 10.
Article in English | MEDLINE | ID: mdl-34376412

ABSTRACT

A 36-year-old woman with levo-transposition of the great arteries presented for a programmed visit. She was asymptomatic and the clinical examination showed no signs of decompensated heart failure. Standard 12-lead ECG showed isorhythmic atrioventricular dissociation. A 24-hour ambulatory recording demonstrated sinus rhythm with intermittent periods of isorhythmic dissociation. This case highlights the association between two rare conditions.


Subject(s)
Transposition of Great Vessels , Adult , Arrhythmias, Cardiac , Arteries , Electrocardiography , Female , Heart Block , Humans , Transposition of Great Vessels/diagnostic imaging
2.
BMJ Case Rep ; 12(6)2019 Jun 11.
Article in English | MEDLINE | ID: mdl-31189544

ABSTRACT

We report a rare case of native valve endocarditis caused by Staphylococcus warneri in an immunocompetent 79-year-old man with known degenerative valvular heart disease but no previous risk factors such as recent invasive treatment or medical implant. The patient presented with heart failure, due to perforation of the mitral valve, and lacked any signs of infection. The diagnosis of endocarditis with S. warneri was established by echocardiography and positive blood cultures.


Subject(s)
Endocarditis, Bacterial/microbiology , Heart Failure/microbiology , Heart Valve Diseases/microbiology , Staphylococcal Infections/complications , Staphylococcus , Aged , Humans , Male , Mitral Valve/microbiology , Staphylococcal Infections/microbiology
3.
Rom J Morphol Embryol ; 57(2 Suppl): 885-891, 2016.
Article in English | MEDLINE | ID: mdl-27833988

ABSTRACT

The commonest cause of head and neck malignancy in pediatric patients is lymphoma. A particular case is the tonsillar lymphoma. Even though unilateral tonsillar enlargement represents an ominous sign for neoplasia, clinical manifestations vary and are non-specific. Therefore, a delayed diagnosis is performed which compromises optimal therapy and hinders the prognosis. We present the case of a 5-year-old boy who was initially diagnosed with obstructive sleep apnea, without reported systemic complaints. Asymmetric tonsillar hypertrophy created the premises for performing a tonsillectomy to rule out malignancy. The pathological evaluation of the resected tonsils revealed a malignant non-Hodgkin's lymphoma, with immunophenotypic features consistent with sporadic type Burkitt lymphoma. The aim of this paper is to emphasize the importance of the histopathological examination and of the immunohistochemistry testing for the prompt and accurate diagnosis of all asymmetric tonsillar hypertrophy in children undergoing tonsillectomy. Furthermore, immunohistochemical diagnosis is vital for establishing a personalized multi-agent chemotherapy regimen, which dramatically improves the survival rate. We recommend histopathological evaluation in all children with asymmetric tonsillar hypertrophy undergoing tonsillectomy for various reasons. Needless to say, it is better to be cautious and exclude the presence of tonsillar lymphoma, than to confront with the severe consequences of misdiagnosis.


Subject(s)
Lymphoma/diagnosis , Sleep Apnea, Obstructive/diagnosis , Tonsillar Neoplasms/diagnosis , Cell Membrane/metabolism , Child , Diagnosis, Differential , Epstein-Barr Virus Infections/pathology , Humans , Immunohistochemistry , Lymphoma/pathology , Male , Palatine Tonsil/pathology , Sleep Apnea, Obstructive/pathology , Tonsillar Neoplasms/pathology
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