[Intra-anesthetic hypothermia]. / Hipotermia intraanestezica.

Oesophageal temperature was recorded after induction of anesthesia, and further, at one, two and three hours. Temperature in the operation hall was continuously monitored. In relation to the temperature in the operating hall the effects on the patient were of three kinds: 1. operating halls with low temperatures (under 21 degrees C) where all the patients become hypothermic; 2. operating halls with an intermediate temperature (21-24 degrees C), where 67% of the patients remain normothermic; 3. operating halls with high temperatures (above 24 degrees C) where all the patients remain normothermic, although these temperatures are uncomfortable for the medical personnel, and increase the septic risk of the patient. When the oesophageal temperature of the patients falls by 0.5 degrees C chills will occur in 40% of the patients. Thermal falls of less than 0.5 degrees C will also determine chills but in only 10.5% of the cases. Immediate postanesthesia chills are also recorded in normothermic patients, but there is a direct relationship between the temperature in the operating hall, the degree of hypothermia and the frequency of chills, while the site of the surgery or the duration of the operation have but an unsignificant influence on intra-anesthetic temperature.

[Neurolysis of the posterior tibial nerve in the tarsal canal--a new therapeutic approach in chronic painless plantar ulcers]. / Neuroliza nervului tibial posterior în canalul tarsian--o noua abordare terapeutica a ulceratiilor cronice.

The paper reports on 14 cases of perforating plantar disease of whom 11 belong to the so-called nonpainful chronic plantar ulceration by compression of the posterior tibial nerve in the tarsal canal. The authors show clinically, neuroelectrically and by neurography with lipiodol that in the case of a diabetic or alcoholic polyneuropathy, the posterior tibial nerve is more vulnerable to the compression existing in the tarsal canal due to the development of a fibrous sclerotic tissue. Exo-endoneurolysis of the posterior tibial nerve associated with a posterior tibial periarterial sympathectomy permitted healing in 7 ulcerations, 2 diminutions of the ulceration dimensions, and only 2 remissions. The four cases of unfavourable results were in patients with old lesions who continued alcohol consumption.

[Nongynecologic abdominal emergencies during pregnancy]. / Urgente abdominale neginecologice în timpul sarcinii.

The paper reports on the authors' experience in the surgical emergency of a special category of patients: pregnant women with acute affections requiring surgery. The clinical aspects, sometimes deceptive, diagnosis difficulties and tactile and technical surgical attitudes are presented in detail.

[Primary exertion thrombophlebitis of the upper extremities: clinical and therapeutic aspects]. / Tromboflebita primitiva "de efort" a membrului toracic: aspecte clinice si terapeutice.

The authors present 4 cases of "effort" thrombophlebitis of the upper limb that were diagnosed both clinically and thrombophlebographically, and in whom classical therapy was applied: total rest, anticoagulants, elevation of the limb. All the cases had sequels of variable intensity, and in 2 of the patients Roos' transaxillary route was used which revealed a double anterior scalenus muscle insertion, and compressive fibro-sclerous tissue. The pathogeny of the affection makes mandatory the removal of extrinsic or intrinsic factors which may generate a new thrombosis or vascular and neurologic sequels.

[Perforated and hemorrhagic duodenal ulcer: the problems of the surgical procedure and technic]. / Ulcerul duodenal perforat si hemoragic, probleme de tactica si tehnica chirurgicala.

The authors analyze five cases of concomitant development of two major complications of duodenal ulcers: perforation and haemorrhage. Particular problems of surgical tactic and technique are discussed.

Experimental studies in transient myocardial ischaemia.

The biology of the myocardium was studied under experimental conditions similar to angina pectoris. In some dogs the myocardium was adapted to ischaemia by progressive coronary occlusion of 1-5 min followed by restoration of circulation during 5 min. In other dogs adaption was followed by 20 to 35 min ischaemia. The animals were sacrificed immediately or after 2-10 days. Transient ischaemia produced less severe alterations then abrupt coronary obstruction. Adaptation followed by 20 and 35 min ischaemia induced foci that undergo cytolysis and scarring of maximum intensity on the 8th day. Activity of enzymes in the mitochondrial suspension, especially of cytochromoxidase, decreases and lysosomal hydrolases increase with focal necroses.

Ultrastructural and biochemical alterations induced by propranolol treatment in experimental myocardial ischaemia.

The effect of propranolol within the first ten days after a transient experimental myocardial ischaemia was investigated. As compared to the untreated control lot, the ultrastructural and biochemical lesions appeared to be much reduced and within reversible limits. Worthy of note was the slight affection of mitochondria revealed by the level of mitochondrial enzymes, the presence of lysosomal and phagolysosomal structures and capillaries of normal aspect, and the absence of cytolysis. The favourable effect of this beta-blocking drug might be attributed to its protective action on the cellular and capillary membrane systems.

Investigations on the morphophysiological basis of revascularization of the myocardium by the Vineberg method.

A study was carried out on the dynamics of vasculogenesis and the formation of mammary-coronary anastomoses within the first seven months after implantation of the internal mammary artery in the left ventricular myocardium, according to the Vineberg method. The efficiency of these anastomoses was demonstrated 4 to 7 months later by the absence of lesions 8 to 10 days after transitory and permanent myocardial ischaemia induced by coronary obliteration. The lesions could not be prevented in the case of thrombosis of the internal mammary artery or when ischaemia was produced concomitantly with the implant or before the mammary-coronary arteriolo-arterial anastomotic network developed.

Experimental study of myocardial bridges.

Myocardial bridges were reproduced in dogs by transfer of a fragment of the left ventricular wall above the upper portion of the anterior interventricular artery. The viability of this bridge was shown by coronarography, anatomic, histologic and electron microscopic studies, illustrating the vascular patency and the integrity of blood vessels and neighbouring myocardium in the cases postoperatively heparinized. The experimental model efficiency was also proved by ECG examinations revealing ischemic distresses induced by compression of the bridge against the underlying artery.