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1.
Bone Jt Open ; 4(5): 363-369, 2023 May 22.
Article in English | MEDLINE | ID: mdl-37212198

ABSTRACT

Aims: Reimers migration percentage (MP) is a key measure to inform decision-making around the management of hip displacement in cerebral palsy (CP). The aim of this study is to assess validity and inter- and intra-rater reliability of a novel method of measuring MP using a smart phone app (HipScreen (HS) app). Methods: A total of 20 pelvis radiographs (40 hips) were used to measure MP by using the HS app. Measurements were performed by five different members of the multidisciplinary team, with varying levels of expertise in MP measurement. The same measurements were repeated two weeks later. A senior orthopaedic surgeon measured the MP on picture archiving and communication system (PACS) as the gold standard and repeated the measurements using HS app. Pearson's correlation coefficient (r) was used to compare PACS measurements and all HS app measurements and assess validity. Intraclass correlation coefficient (ICC) was used to assess intra- and inter-rater reliability. Results: All HS app measurements (from 5 raters at week 0 and week 2 and PACS rater) showed highly significant correlation with the PACS measurements (p < 0.001). Pearson's correlation coefficient (r) was constantly over 0.9, suggesting high validity. Correlation of all HS app measures from different raters to each other was significant with r > 0.874 and p < 0.001, which also confirms high validity. Both inter- and intra-rater reliability were excellent with ICC > 0.9. In a 95% confidence interval for repeated measurements, the deviation of each specific measurement was less than 4% MP for single measurer and 5% for different measurers. Conclusion: The HS app provides a valid method to measure hip MP in CP, with excellent inter- and intra-rater reliability across different medical and allied health specialties. This can be used in hip surveillance programmes by interdisciplinary measurers.

2.
J Pediatr Orthop B ; 27(5): 387-390, 2018 Sep.
Article in English | MEDLINE | ID: mdl-29578934

ABSTRACT

A total of 28 068 infants were studied to investigate whether universal ultrasound screening for developmental dysplasia of the hip results in fewer delayed presentations than selective screening, and whether the screening protocol affects subsequent treatment. The rate of delayed presentation was not lower with selective screening compared with universal screening but all cases of delayed presentation in this cohort were administrative errors. There were no sonographic errors (false-negatives). The treatment rate was significantly higher with universal screening but infants were treated earlier and were significantly less likely to require any surgical intervention. Those requiring surgery were less likely to require open reduction or pelvic osteotomy.


Subject(s)
Hip Dislocation, Congenital/diagnostic imaging , Neonatal Screening , Ultrasonography , Delayed Diagnosis , False Negative Reactions , Female , Humans , Infant , Infant, Newborn , Male , Physical Examination , Retrospective Studies , Risk Factors , Time Factors
3.
Bone ; 81: 468-477, 2015 Dec.
Article in English | MEDLINE | ID: mdl-26303288

ABSTRACT

The mechanical integrity of the bone-implant system is maintained by the process of bone remodeling. Specifically, the interplay between bone resorption and bone formation is of paramount importance to fully understand the net changes in bone structure occurring in the peri-implant bone, which are eventually responsible for the mechanical stability of the bone-implant system. Using time-lapsed in vivo micro-computed tomography combined with new composite material implants, we were able to characterize the spatio-temporal changes of bone architecture and bone remodeling following implantation in living mice. After insertion, implant stability was attained by a quick and substantial thickening of the cortical shell which counteracted the observed loss of trabecular bone, probably due to the disruption of the trabecular network. Within the trabecular compartment, the rate of bone formation close to the implant was transiently higher than far from the implant mainly due to an increased mineral apposition rate which indicated a higher osteoblastic activity. Conversely, in cortical bone, the higher rate of bone formation close to the implant compared to far away was mostly related to the recruitment of new osteoblasts as indicated by a prevailing mineralizing surface. The behavior of bone resorption also showed dissimilarities between trabecular and cortical bone. In the former, the rate of bone resorption was higher in the peri-implant region and remained elevated during the entire monitoring period. In the latter, bone resorption rate had a bigger value away from the implant and decreased with time. Our approach may help to tune the development of smart implants that can attain a better long-term stability by a local and targeted manipulation of the remodeling process within the cortical and the trabecular compartments and, particularly, in bone of poor health.


Subject(s)
Bone Remodeling/physiology , Bone and Bones/physiology , Osteogenesis/physiology , Prostheses and Implants , Animals , Artifacts , Bone Density , Bone Resorption , Bone and Bones/diagnostic imaging , Female , Metals/chemistry , Mice , Mice, Inbred C57BL , Osseointegration/physiology , Osteoblasts/metabolism , Osteoclasts/metabolism , Osteoporosis , Prosthesis Implantation , Reproducibility of Results , X-Ray Microtomography
4.
J Pediatr Orthop B ; 23(2): 103-6, 2014 Mar.
Article in English | MEDLINE | ID: mdl-24322535

ABSTRACT

Outcomes of nonoperative treatment for developmental dysplasia of the hip were compared between two centres. Eighty children in Centre A underwent staged weaning of the Pavlik harness once three consecutive weekly ultrasounds showed Graf Grade I hips, whereas in 48 children in Centre B, the harness was removed immediately. No statistically significant difference was found in the rate of reintervention (repeat harness treatment, closed or open reduction), avascular necrosis or acetabular index between the two methods, although there was a nonsignificant trend towards higher reintervention rate and lower avascular necrosis rate with immediate harness removal. Age at start of treatment significantly impacted upon initial harness success, reinterventions and avascular necrosis.


Subject(s)
Hip Dislocation, Congenital/therapy , Orthopedic Procedures/instrumentation , Orthotic Devices , Equipment Design , Equipment Safety , Female , Follow-Up Studies , Hip Dislocation, Congenital/physiopathology , Humans , Infant , Infant, Newborn , Male , Range of Motion, Articular , Recovery of Function , Retrospective Studies , Time Factors , Treatment Outcome
5.
J Pediatr Orthop B ; 21(6): 596-601, 2012 Nov.
Article in English | MEDLINE | ID: mdl-22668574

ABSTRACT

A systematic review of the literature was performed to establish whether direct repair of the pars defect or intervertebral fusion achieves better Oswestry Disability Index scores in adolescent spondylolysis or low-grade spondylolisthesis. Nine studies fulfilled the inclusion criteria, reporting a minimum total of 80 direct repairs and 108 fusions because of presumed replication of data between studies. Little statistically or clinically significant difference could be established between the two interventions. The only comparative study showed improved long-term outcome with fusion. Further well-designed prospective comparative studies are required to establish the optimum treatment for this condition.


Subject(s)
Spinal Fusion/methods , Spine/surgery , Spondylolysis/surgery , Disability Evaluation , Humans , Recovery of Function , Spine/physiopathology , Spondylolysis/physiopathology , Treatment Outcome
6.
J Child Orthop ; 6(1): 75-80, 2012 Mar.
Article in English | MEDLINE | ID: mdl-23450379

ABSTRACT

PURPOSE: Unstable paediatric diaphyseal both-bone forearm fractures requiring fixation have traditionally been treated with rigid internal fixation with plate and screws. Intramedullary stabilisation has grown in popularity over the last 25 years but may be associated with rotational deformity and subsequent loss of pronosupination. This systematic review aims to establish which treatment method provides better functional outcome. METHODS: A systematic review of the published literature was performed, searching Medline, Embase, Pubmed and the Cochrane Library for English-language studies comparing intramedullary nailing with plate and screws in patients less than 18 years old with both-bone diaphyseal forearm fractures. RESULTS: Seven studies met the inclusion criteria. They were all retrospective comparative studies (level III or IV). One was age- and sex-matched. Three looked specifically at older children. No study reported a significant difference in functional outcome with either treatment. CONCLUSIONS: The currently available literature shows no difference in functional outcome between intramedullary nailing and plate and screw fixation, even in older children with less remodelling potential. Intramedullary nailing may therefore be the treatment of choice for simple fracture patterns due to shorter operative time, better cosmesis and ease of removal. Plating may still have a role in more complex injuries.

7.
J Pediatr Orthop B ; 19(1): 22-6, 2010 Jan.
Article in English | MEDLINE | ID: mdl-19901850

ABSTRACT

The management of developmental dysplasia of the hip, particularly the timing of closed reduction with regard to the presence of the femoral head ossific nucleus, is controversial. The clinical and radiological outcome was assessed in a strictly defined group of 48 hips in 42 patients with an average of 11.1 years follow-up. One hundred percent of patients had an excellent or good result at final follow-up; 8.3% showed evidence of avascular necrosis and six hips underwent further surgery after closed reduction. There was no relationship between the presence or absence of an ossific nucleus at the time of closed reduction and the final outcome. In this well-defined group, closed reduction is safe and provides excellent results in the long term.


Subject(s)
Femur Head/pathology , Hip Dislocation, Congenital/therapy , Osteogenesis/physiology , Arthrography , Casts, Surgical , Female , Hip Dislocation, Congenital/diagnostic imaging , Hip Dislocation, Congenital/physiopathology , Humans , Infant , Male , Manipulation, Orthopedic , Postoperative Complications/pathology , Treatment Outcome
8.
Article in English | MEDLINE | ID: mdl-19284697

ABSTRACT

BACKGROUND: Shoulder instability is a common condition, particularly affecting a young, active population. Open capsulolabral repair is effective in the majority of cases, however arthroscopic techniques, particularly using suture anchors, are being used with increasing success. METHODS: 15 patients with shoulder instability were operated on by a single surgeon (VK) using BioKnotless anchors (DePuy Mitek, Raynham, MA). The average length of follow-up was 21 months (17 to 31) with none lost to follow-up. Constant scores in both arms, patient satisfaction, activity levels and recurrence of instability was recorded. RESULTS: 80% of patients were satisfied with their surgery. 1 patient suffered a further dislocation and another had recurrent symptomatic instability. The average constant score returned to 84% of that measured in the opposite (unaffected) shoulder. There were no specific post-operative complications encountered. CONCLUSION: In terms of recurrence of symptoms, our results show success rates comparable to other methods of shoulder stabilisation. This technique is safe and surgeons familiar with shoulder arthroscopy will not encounter a steep learning curve. Shoulder function at approximately 2 years post repair was good or excellent in the majority of patients and it was observed that patient satisfaction was correlated more with return to usual activities than recurrence of symptoms.

9.
Cases J ; 2: 102, 2009 Jan 29.
Article in English | MEDLINE | ID: mdl-19178718

ABSTRACT

There are many conditions ranging from the benign to the malignant, which can present with enlargement of one or more digits. An understanding of the differential diagnosis is important such that the potentially serious aetiologies are not missed and patients can therefore be treated appropriately. We present two patients, a male and a female aged 58 and 49 respectively, who presented to orthopaedic surgeons with gross enlargement of the toes. There were significant delays to presentation in both cases. Histological and microbiological analysis revealed that chronic, untreated infection was the most likely cause in both cases. Both patients were successfully treated by amputation of the offending digits. Congenital, infective, inflammatory and neoplastic conditions may all cause enlargement of a digit. The cause should be thoroughly sought prior to deciding upon management. Amputation can be successful, enables definitive tissue diagnosis and allows quick return to normal activities. The correct level must be identified pre-operatively.

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