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J Fr Ophtalmol ; 26(9): 905-10, 2003 Nov.
Article in French | MEDLINE | ID: mdl-14631274

ABSTRACT

PURPOSE: To report and analyze the circumstances of uveal melanoma detection. METHODS: The records of 143 consecutive patients diagnosed in the Ophthalmology Department of Gustave Roussy Institute between September 1994 and September 2001 were analyzed. The study included 66 females and 77 males, aged from 21 to 91 years (mean, 62.75 years). RESULTS: The first symptom was decreased visual acuity in 37% of cases. In 34.9%, there was no functional sign and a systematic fundus exam provided the diagnosis. Of the 143 patients, 18.8% presented alteration of the visual field or scotoma, 9.9% complained of phosphenes, 9% complained of metamorphopsia, and 6.5% complained of floaters. In 5.5% of cases, there was documented tumor growth. In 2%, the presence of extrascleral exteriorization was the first sign. At the time of diagnosis, anterior tumors tended to be significantly larger than posterior tumors (p<0.007). Smaller lesions were significantly associated with a systematic detection of the tumor (p<0.005). Liver metastasis occurred more frequently with ciliary body melanomas (p<0.001), which were more frequently the largest lesions. CONCLUSION: These results emphasize the importance of early detection of uveal melanoma. We recommended frequent fundus examination after pupil dilatation.


Subject(s)
Choroid Neoplasms/diagnosis , Melanoma/diagnosis , Uveal Neoplasms/diagnosis , Adult , Age Distribution , Aged , Aged, 80 and over , Choroid Neoplasms/complications , Choroid Neoplasms/epidemiology , Ciliary Body , Diagnosis, Differential , Female , France/epidemiology , Humans , Liver Neoplasms/secondary , Male , Melanoma/complications , Melanoma/epidemiology , Middle Aged , Ophthalmoscopy , Phosphenes , Prognosis , Retrospective Studies , Scotoma/etiology , Sex Distribution , Time Factors , Uveal Neoplasms/complications , Uveal Neoplasms/epidemiology , Vision Disorders/etiology , Visual Acuity , Visual Fields
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