1.
J Org Chem
; 71(12): 4525-9, 2006 Jun 09.
Article
in English
| MEDLINE
| ID: mdl-16749784
ABSTRACT
Either silver trifluoromethanesulfonate or a mixture of gold(I) chloride, silver trifluoromethanesulfonate, and triphenylphosphine catalyze the formation of pyrroles from substituted beta-alkynyl ketones and amines. The reactions proceed by using 5 mol % of catalyst with yields of isolated pyrroles ranging from 13% to 92%. Sixteen examples are used to compare the effectiveness of each catalyst.