Your browser doesn't support javascript.
loading
Show: 20 | 50 | 100
Results 1 - 20 de 50
Filter
1.
Aust Dent J ; 65(4): 259-268, 2020 12.
Article in English | MEDLINE | ID: mdl-32506570

ABSTRACT

BACKGROUND: Periodontal infection may induce systemic vascular/endothelial dysfunction signifying a potential link between hypertension and periodontitis. METHODS: A convenience sample of 204 adults attending a university teaching hospital without (C: control) or with essential hypertension [EH; n = 102, duration (mean ± SD) 11.4 ± 6.9 years] was surveyed in this cross sectional study. Patients with concomitant systemic conditions were excluded. Dental history, oral hygiene habits and blood pressure were recorded. Plaque score (Pl%), bleeding on probing (BOP%), probing pocket depth (PPD) and probing attachment level (PAL) were noted and periodontitis severity was determined according to AAP/CDC case definition guidelines. RESULTS: Both groups exhibited poor oral hygiene. EH group had higher mean full-mouth PAL/PPD (3.16/2.73 vs. 2.51/2.40, P < 0.001). 51.0%/30.4% of the EH/C participants had severe periodontitis (P < 0.001). Regression analysis indicated systolic blood pressure, age, smoking and BOP% were associated with more severe periodontitis (r2  = 0.207, P < 0.05) while BOP%, PAL and fewer missing teeth were associated with worse mean PPD (r2  = 0.612, P < 0.05). CONCLUSIONS: Within the limitations of this study, the majority of hospital attendees surveyed exhibited poor plaque control, while periodontitis severity was found to be associated with EH, and smoking.


Subject(s)
Hospitals, General , Adult , Cross-Sectional Studies , Essential Hypertension , Hong Kong/epidemiology , Humans , Periodontal Attachment Loss , Periodontal Index
2.
J Periodontal Res ; 53(3): 440-445, 2018 Jun.
Article in English | MEDLINE | ID: mdl-29574763

ABSTRACT

BACKGROUND AND OBJECTIVE: Glycine powder air-polishing (GPAP) is an alternative approach to removing subgingival plaque biofilms for effective periodontal therapy. This study aimed to investigate the effect of subgingival GPAP as an additional approach to nonsurgical periodontal treatment in subjects with chronic periodontitis. MATERIAL AND METHODS: Twenty-seven nonsmoking subjects were recruited. Two quadrants in each subject were randomly assigned, according to a split-mouth design, to receive scaling and root planing (SRP) and GPAP (Test group) or SRP and air flushing with water (Control group) at sites with probing depth ≥5 mm. Clinical parameters, gingival crevicular fluid volumes and the concentrations of interleukin-1ß and interleukin-1ra in gingival crevicular fluid were measured at baseline and 1, 3 and 6 months after the treatments. RESULTS: At baseline, no statistically significant difference in periodontal and gingival crevicular fluid parameters was found between the Test and Control groups. Overall, the periodontal conditions of all subjects showed significant improvement after the treatments. Notably, the Test group showed greater reduction in gingival crevicular fluid volume (0.37 ± 0.26 µL) than the Control group (0.23 ± 0.30 µL) at 3 months (P < .05). The gingival crevicular fluid levels of interleukin-1ß and interleukin-1ra showed a significant decrease in both groups at 6 months, and no significant difference was found between the groups. CONCLUSION: These preliminary results suggest that GPAP, as an additional approach to nonsurgical periodontal treatment, may be beneficial for the short-term improvement of subclinical inflammation when measured by gingival crevicular fluid volume. Further longitudinal studies with larger sample sizes are required to clarify the exact benefits of GPAP treatment for controlling inflammation and maintaining long-term periodontal health.


Subject(s)
Chronic Periodontitis/therapy , Dental Plaque/therapy , Glycine/therapeutic use , Periodontal Debridement/methods , Adolescent , Adult , Aged , Asian People , Cytokines/analysis , Dental Plaque Index , Dental Polishing/methods , Dental Scaling/methods , Gingival Crevicular Fluid/chemistry , Hong Kong , Humans , Inflammation/therapy , Interleukin-1beta/analysis , Middle Aged , Periodontal Attachment Loss , Periodontal Debridement/instrumentation , Periodontal Index , Periodontal Pocket , Root Planing/methods , Single-Blind Method , Surveys and Questionnaires , Ultrasonic Therapy/methods , Young Adult
3.
J Periodontal Res ; 53(3): 324-333, 2018 Jun.
Article in English | MEDLINE | ID: mdl-29105779

ABSTRACT

BACKGROUND AND OBJECTIVE: Risk for deterioration in treated aggressive periodontitis (AgP) individuals remained unclear. This retrospective cohort study investigated 7-26 years of periodontal outcomes and oral health-related quality of life (OHRQoL) of young adults with advanced periodontitis. MATERIAL AND METHODS: Eighty-nine previously treated patients with AgP were re-examined. Clinical and radiographic parameters before treatment discontinuation and at re-examination were compared. OHRQoL at re-call was assessed with the short-form Oral Health Impact Profile (OHIP-14S). RESULTS: None of the subjects adhered to suggested periodontal therapy and maintenance after discharge. Mean percentage of sites with probing pocket depth (PPD) ≥6 mm at re-examination was 4.5 ± 5.9%. A total of 182 teeth had been lost over time. Tooth loss rate was 0.14/patient/year. From 68 subjects with documented favorable treatment outcomes, higher percentage of sites with PPD ≥6 mm at re-examination and higher radiographic proximal bone loss was associated with current smoking status. Patients with AgP with <20 teeth at re-call had worse OHRQoL than those with ≥20 teeth. Patients with higher full-mouth mean PPD also reported poorer OHRQoL. CONCLUSION: Treatment in patients with AgP who smoke and neglect proper supportive care, risk periodontal disease progression. Substantial tooth loss and higher full-mouth mean PPD led to poorer OHRQoL in this cohort.


Subject(s)
Aggressive Periodontitis/therapy , Oral Health/statistics & numerical data , Tooth Loss/therapy , Adolescent , Adult , Aggressive Periodontitis/diagnosis , Aggressive Periodontitis/epidemiology , Alveolar Bone Loss/epidemiology , Dental Plaque/epidemiology , Dental Plaque/therapy , Female , Follow-Up Studies , Hong Kong/epidemiology , Humans , Male , Periodontal Attachment Loss , Periodontal Index , Periodontal Pocket/classification , Periodontal Pocket/epidemiology , Quality of Life , Retrospective Studies , Surveys and Questionnaires , Tooth Loss/diagnosis , Tooth Loss/epidemiology , Treatment Outcome , Young Adult
4.
Aust Dent J ; 62(2): 152-160, 2017 Jun.
Article in English | MEDLINE | ID: mdl-27391220

ABSTRACT

BACKGROUND: The current retrospective cross-sectional study investigated 5-18-year treatment outcomes in subjects who did not complete a recommended course of periodontal therapy. METHODS: Sixty-five subjects who voluntarily discontinued therapy were recalled. The subjects' demographic data and dental history since discontinuation of periodontal treatment were collected via questionnaires. The subjects' periodontal condition, radiographic data and individual tooth-based prognosis at pre-discontinuation and recall were compared. RESULTS: A total of 229 teeth had been lost over time, mainly due to periodontal reasons. Upper and lower molars were most frequently lost. Rate of tooth loss (0.38/patient per year) was comparable to untreated patients. Deterioration in periodontal health in terms of increased percentage of sites with bleeding on probing (BOP) and sites with probing pocket depths (PPD) of 6 mm or more at re-examination was observed. Positive correlations were found between tooth loss and: (i) years since therapy discontinued; (ii) percentage of sites with PPD of 6 mm or more at pre-discontinuation; and (iii) at re-examination. Percentage of sites with PPD of 6 mm or more at recall was positively correlated with periodontal tooth loss and negatively correlated with percentage of sites without BOP. CONCLUSIONS: Patients not completing a course of periodontal therapy are at risk of further tooth loss and deterioration in periodontal conditions over time.


Subject(s)
Periodontal Diseases/therapy , Periodontal Index , Periodontal Pocket/surgery , Tooth Loss/etiology , Adult , Aged , Aged, 80 and over , Cross-Sectional Studies , Female , Follow-Up Studies , Humans , Male , Middle Aged , Molar , Prognosis , Retrospective Studies , Tooth Loss/therapy , Treatment Outcome
5.
Br Dent J ; 213(3): 111-21, 2012 Aug.
Article in English | MEDLINE | ID: mdl-22878307

ABSTRACT

Periodontal diseases are diagnosed on the basis of clinical signs, with radiographs assisting in treatment planning decisions and in the delivery of periodontal care. In the first instance, use of a screening system, to screen out patients with minimal or no disease, and to screen in those with disease requiring full diagnosis and treatment planning for periodontitis, is a very helpful approach. The full diagnostic approach relies on periodontal probing and the response to probing. Periodontal probing depth measurements and periodontal attachment level registrations are recordings of clinical findings, which depend upon the state of health of the periodontal tissues to a large extent.


Subject(s)
Dental Plaque/diagnosis , Gingiva/physiopathology , Periodontal Diseases/diagnosis , Physical Examination/methods , Humans , Periodontal Diseases/classification , Physical Examination/instrumentation , Risk Assessment/methods , Severity of Illness Index
6.
Eur J Dent Educ ; 16(1): e96-e105, 2012 Feb.
Article in English | MEDLINE | ID: mdl-22251360

ABSTRACT

OBJECTIVES: To determine how prepared for dental practice graduates from the integrated problem-based learning (PBL) dental undergraduate curriculum at The University of Hong Kong (HKU) perceive themselves to be and to identify factors associated with self-perceived preparedness. MATERIALS AND METHODS: A postal questionnaire was sent to five cohorts of dentists who had graduated from HKU's integrated PBL curriculum between 2004 and 2008. Using a 4-point Likert scale, the questionnaire assessed the self-perceived level of preparedness in 59 competencies grouped in nine domains. Responses were dichotomised into 'poorly prepared' and 'well prepared'. RESULTS: The response rate was 66% (159/241). The mean proportion (±standard deviation) of respondents indicating well-preparedness was 72.0±15.1% overall, and for each domain was as follows: general patient management, 93.1±12.1%; practice management, 81.0±22.2%; periodontology and dental public health, 73.5±19.3%; conservative dentistry, 92.5±13.1%; oral rehabilitation, 62.8±24.0%; orthodontics, 23.0±32.9%; managing children and special-needs patients, 64.8±28.9%; oral and maxillofacial surgery, 52.2±25.2%; and drug and emergency management, 84.7±22.6%. The odds of self-perceived well-preparedness were increased for cohorts graduating in 2004 and 2005 and graduates working in a non-solo dental practice. CONCLUSIONS: Dental graduates of HKU's integrated PBL curriculum felt well prepared for the most fundamental aspects of dental practice. However, apparent deficiencies of training in orthodontics and oral and maxillofacial surgery will need to be addressed by continuing education, postgraduate training and planning for the new 6-year undergraduate curriculum in 2012.


Subject(s)
Clinical Competence , Curriculum , Education, Dental/organization & administration , Problem-Based Learning , Students, Dental/psychology , Adult , Analysis of Variance , Female , Hong Kong , Humans , Male , Regression Analysis , Surveys and Questionnaires , Universities
7.
J Periodontal Res ; 46(1): 89-96, 2011 Feb.
Article in English | MEDLINE | ID: mdl-20860592

ABSTRACT

BACKGROUND AND OBJECTIVE: In recent years, there has been a growing interest in the use of dental lasers for treatment of periodontal diseases. The purpose of this short-term clinical trial was to evaluate the effects of a combination of photodynamic therapy with low-level laser therapy as an adjunct to nonsurgical treatment of chronic periodontitis. MATERIAL AND METHODS: Twenty-four nonsmoking adults with untreated chronic periodontitis were randomly assigned in a split-mouth design to receive scaling and root debridement with or without one course of adjunctive photodynamic therapy and low-level laser therapy within 5 d. Plaque, bleeding on probing, probing depth and gingival recession were recorded at baseline, 1 and 3 mo after the treatment. Gingival crevicular fluid was collected for assay of interleukin-1ß levels at baseline, 1 wk and 1 mo. RESULTS: The test teeth achieved greater reductions in the percentage of sites with bleeding on probing and in mean probing depth at 1 mo compared with the control teeth (p < 0.05). A significant decrease in gingival crevicular fluid volume was observed in both groups at 1 wk (p < 0.001), with a further decrease at 1 mo in the test sites (p < 0.05). The test sites showed a greater reduction of interleukin-1ß levels in gingival crevicular fluid at 1 wk than the control sites (p < 0.05). No significant differences in periodontal parameters were found between the test and control teeth at 3 mo. CONCLUSIONS: The present study suggests that a combined course of photodynamic therapy with low-level laser therapy could be a beneficial adjunct to nonsurgical treatment of chronic periodontitis on a short-term basis. Further studies are required to assess the long-term effectiveness of the combination of photodynamic therapy with low-level laser therapy as an adjunct in nonsurgical treatment of periodontitis.


Subject(s)
Chronic Periodontitis/drug therapy , Chronic Periodontitis/radiotherapy , Low-Level Light Therapy , Photochemotherapy , Adult , Combined Modality Therapy , Dental Scaling , Female , Gingival Crevicular Fluid/chemistry , Humans , Interleukin-1beta/analysis , Male , Middle Aged , Periodontal Debridement , Single-Blind Method , Treatment Outcome
8.
J Dent Res ; 89(10): 1086-90, 2010 Oct.
Article in English | MEDLINE | ID: mdl-20671206

ABSTRACT

Root caries is common in institutionalized elders, and effective prevention methods are needed. This clinical trial compared the effectiveness of four methods in preventing new root caries. From 21 residential homes, 306 generally healthy elders having at least 5 teeth with exposed sound root surfaces were randomly allocated into one of four groups: (1) individualized oral hygiene instruction (OHI); (2) OHI and applications of 1% chlorhexidine varnish every 3 months; (3) OHI and applications of 5% sodium fluoride varnish every 3 months; and (4) OHI and annual applications of 38% silver diamine fluoride (SDF) solution. Two-thirds (203/306) of the elders were followed for 3 years. Mean numbers of new root caries surfaces in the four groups were 2.5, 1.1, 0.9, and 0.7, respectively (ANOVA, p < 0.001). SDF solution, sodium fluoride varnish, and chlorhexidine varnish were more effective in preventing new root caries than giving OHI alone.


Subject(s)
Root Caries/prevention & control , Aged , Anti-Infective Agents, Local/administration & dosage , Anti-Infective Agents, Local/therapeutic use , Cariostatic Agents/therapeutic use , Chlorhexidine/administration & dosage , Chlorhexidine/therapeutic use , DMF Index , Female , Fluorides, Topical/therapeutic use , Follow-Up Studies , Humans , Institutionalization , Male , Nursing Homes , Oral Hygiene , Patient Education as Topic , Quaternary Ammonium Compounds/therapeutic use , Residential Facilities , Self Care , Silver Compounds , Sodium Fluoride/therapeutic use , Toothbrushing/methods , Toothpastes/therapeutic use , Treatment Outcome
9.
Aust Dent J ; 54 Suppl 1: S27-43, 2009 Sep.
Article in English | MEDLINE | ID: mdl-19737266

ABSTRACT

Radiographs are an integral component of a periodontal assessment for those with clinical evidence of periodontal destruction. A close consideration of the current approach to periodontal diagnosis compatible with the current classification of periodontal diseases reveals that radiographs only inform with respect to diagnosis for a small proportion of conditions. The area in periodontal assessment in which radiographs play a pivotal role is in treatment planning. A variety of radiographic exposure types assist in the development of periodontal treatment plans. This "therapeutic yield" can be achieved by panoramic oral radiographs supplemented by selective intra-oral views. Digital panoramic oral radiographs viewed on screen appear to offer advantages over printouts or films. Newer imaging approaches, such as cone-beam computed (digital volume) tomography, may come to show some usefulness but experience has shown that digital subtraction radiography will probably remain a research tool without much clinical application.


Subject(s)
Patient Care Planning , Periodontal Diseases/diagnostic imaging , Cone-Beam Computed Tomography , Humans , Periodontal Diseases/therapy , Radiography, Bitewing , Radiography, Dental, Digital , Radiography, Panoramic , Subtraction Technique
10.
Photomed Laser Surg ; 27(2): 287-93, 2009 Apr.
Article in English | MEDLINE | ID: mdl-18785848

ABSTRACT

OBJECTIVE: To evaluate the adjunctive effect of a low-power He-Ne laser in the non-surgical periodontal treatment of patients with moderate to advanced chronic periodontitis. BACKGROUND DATA: Laser applications in dental treatment are now more common in the literature. However, limited data are available on the potential effects of the low-power laser as an adjunct to non-surgical periodontal therapy for managing patients with moderate to advanced periodontal disease. MATERIALS AND METHODS: Sixteen patients with probing pocket depth (PPD) > or =5 mm and comparable bone defects on both sides of the mouth were recruited. Supragingival plaque (PL), bleeding on probing (BOP), PPD, and probing attachment level (PAL) were recorded at baseline and at 3, 6, 9, and 12 mo, while gingival crevicular fluid (GCF) samples and standardized intra-oral radiographs for digital subtraction radiography were taken at baseline and at 1, 3, 6, 9, and 12 mo. After non-surgical mechanical periodontal treatment, the test sites were selected randomly and irradiated with a low-power He-Ne laser (output power 0.2 mW) for 10 min for a total of eight times in the first 3-mo period, while the control sites received no additional treatment. RESULTS: PL percentage (83-16%) and BOP percentage (95-34%) decreased significantly after 12 mo. Statistically significant changes in reductions of PPD and GCF volume, gain in PAL, and increase in recession were seen in both test and control sites when compared to baseline (p < 0.05). No statistically significant differences in any clinical parameters or radiographic findings were found between the test and control sites. Changes in GCF volume were significant only at 3 mo in the test sites. CONCLUSION: Within the limits of this pilot study, the use of the low-power He-Ne laser as an adjunct to non-surgical periodontal therapy in patients with moderate to advanced chronic periodontitis did not seem to provide additional clinical benefit.


Subject(s)
Chronic Periodontitis/radiotherapy , Low-Level Light Therapy , Adult , Chronic Periodontitis/diagnostic imaging , Female , Humans , Lasers, Gas , Male , Middle Aged , Periodontal Pocket/radiotherapy , Pilot Projects , Radiography
11.
J Dent Res ; 85(10): 929-32, 2006 Oct.
Article in English | MEDLINE | ID: mdl-16998134

ABSTRACT

Successful use of atraumatic restorative treatment (ART) in children has been reported, but little information is available regarding its use in older adults. The hypothesis of this study was that survival rates of root restorations placed by both ART and the conventional technique were similar. Root-surface caries lesions in 103 institutionalized elders in Hong Kong were treated randomly by either: (1) the conventional approach-caries removed by dental burs, and the cavity filled with light-cured resin-modified glass ionomer; or (2) the ART approach-caries removed by hand instruments, and the cavity filled with chemically cured high-strength glass ionomer. In total, 84 conventional and 78 ART restorations were placed. After 12 months, 63 conventional and 59 ART restorations were reviewed, and the respective 12-month survival rates were 91.7% and 87.0% (p > 0.05). It is concluded that the survival rates of both types of root restorations were high and similar.


Subject(s)
Dental Care for Aged/methods , Dental Cavity Preparation/methods , Dental Restoration, Permanent/methods , Root Caries/therapy , Age Factors , Aged , Aged, 80 and over , Dental Restoration Failure , Double-Blind Method , Follow-Up Studies , Glass Ionomer Cements , Humans , Nursing Homes , Residential Facilities , Survival Analysis , Treatment Outcome
12.
Hong Kong Med J ; 9(4): 271-7, 2003 Aug.
Article in English | MEDLINE | ID: mdl-12904615

ABSTRACT

OBJECTIVE: To review the effects of tobacco use on oral health, with particular emphasis on the effects of periodontal diseases, dental implant failures, and risk of development of oral cancers and precancers. DATA SOURCES: Medline literature search (1977-2002). STUDY SELECTION: Key words for the literature search were 'tobacco smoking', 'periodontal disease', 'dental implant', and 'oral cancers and precancers'. DATA EXTRACTION: Evidence-based literature review. DATA SYNTHESIS: The prevalence and severity of periodontal diseases in their various forms are higher among smokers than among non-smokers. The success of dental implant treatments is significantly influenced by addiction to tobacco smoking. The failure rate of implant osseointegration is considerably higher among smokers, and maintenance of oral hygiene around the implants and risk of peri-implantitis are adversely affected by smoking. The risks of developing oral cancers and precancers are greater in smokers. Betel nut chewing and smokeless tobacco produce similar risk to cancer incidence as tobacco smoking. Cessation of tobacco use has a beneficial effect on halting the progression of periodontal diseases and on the outcome of periodontal therapy. CONCLUSIONS: Medical and dental teams should be aware of oral problems associated with tobacco use. Counselling on smoking cessation and smoking prevention programmes should be an integral component of medical and dental teaching and practice.


Subject(s)
Carcinoma, Squamous Cell/etiology , Mouth Neoplasms/etiology , Oral Health , Periodontal Diseases/etiology , Tobacco Use Disorder/complications , Carcinoma, Squamous Cell/pathology , Counseling , Dental Implants , Humans , Mouth Neoplasms/pathology , Periodontal Diseases/pathology , Prosthesis Failure , Smoking/adverse effects , Smoking Cessation , Tobacco Use Disorder/therapy , Tobacco, Smokeless/adverse effects
13.
J Clin Periodontol ; 30(2): 114-8, 2003 Feb.
Article in English | MEDLINE | ID: mdl-12622852

ABSTRACT

OBJECTIVES: To calibrate and validate a digital subtraction radiography system using scanned images for quantification of alveolar bone changes by means of computer-assisted densitometric image analysis (CADIA) in vitro. MATERIALS AND METHODS: Noise levels were determined using 10 standardized periapical radiographs of the same lower molar region in a human dry skull. For validation of the system, radiographs were taken before and after bovine bone particles in measures with increments of 2 mg weighing from 2 to 20 mg were added into each socket of three dry skulls. Radiographs were developed and scanned into a computer with a flatbed scanner. After digitization, the images were subjected to alignment, normalization and subtraction. Appropriate regions of interest (ROIs) were selected and their CADIA values were calculated for the determination of noise levels, and correlations between the CADIA values and the actual bone mass were performed. RESULTS: When the threshold value was 7, the percentage of pixels deviating from the set threshold value was small (0-11.3%). There were statistically significant correlations between the actual bone mass and the CADIA value for anterior sockets (p<0.001, r2=0.89) and posterior sockets (p<0.001, r2=0.9). For pooled data of both anterior and posterior sockets, the correlation was also statistically significant (p<0.001, r2=0.88). CONCLUSIONS: A high and statistically significant correlation between the actual bone mass and CADIA value was obtained, which suggests that the system could be suitable for the detection of small alveolar bone changes.


Subject(s)
Alveolar Bone Loss/diagnostic imaging , Radiography, Dental, Digital , Subtraction Technique , Tooth Socket/diagnostic imaging , Absorptiometry, Photon , Animals , Artifacts , Calibration , Cattle , Humans , Least-Squares Analysis , Radiographic Image Interpretation, Computer-Assisted , Reproducibility of Results , Sensitivity and Specificity
14.
Arch Oral Biol ; 48(2): 117-23, 2003 Feb.
Article in English | MEDLINE | ID: mdl-12642230

ABSTRACT

Sample groups of children (n=50) and adults (n=38) were selected from pools of 207 children, (11-13-year olds from two primary schools) and 94 adults (25-44-year olds from four governmental agencies) who were the subjects of an oral health survey among Tibetans living in Lhasa, Tibet Autonomous Region. Mean ages of the study groups of children (38% females) and adults (61% females) were 11.6+/-0.9 and 37.1+/-6.1 years, respectively. All had lived in Tibet since birth. Oral rinse samples were selective cultured to isolate, quantify and speciate aerobic and facultatively anaerobic Gram-negative rods (using the API 20E kit) and yeasts (using API 20C AUX and API ZYM kits). For children, the isolation rates for oral coliform bacteria and yeasts were 84 and 14%, respectively, for adults, the respective rates were 26 and 40%. The corresponding quantities of coliforms/yeasts for children and adults were 0.4+/-1.6 x 10(3)c.f.u./15.8+/-72.3 and 0.2+/-0.6 x 10(3)c.f.u./57.2+/-137.5c.f.u. per millilitre oral rinse, respectively. Aerobic and facultatively anaerobic Gram-negative rods and Stenotrophomonas maltophilia, a free-living saprophytic and ubiquitous bacterial species of wide geographic distribution, were significantly more frequently recovered from the children's oral rinses. The isolation rates of facultatively anaerobic Gram-negative rods in adults and yeasts in both groups were similar to those found in similar cohorts from southern China in earlier studies. Randomly amplified polymeric DNA analysis showed that the S. maltophilia spp. isolated from children were of several different clonal types and were school specific. This study shows that the colonisation rate of facultatively anaerobic Gram-negative rods in adults and yeasts in both groups are similar to those in populations living at lower altitudes, the native young, urban Tibetans appear to exhibit a high oral carriage rate of S. maltophilia spp.


Subject(s)
Gram-Negative Facultatively Anaerobic Rods/isolation & purification , Gram-Positive Rods/isolation & purification , Mouth/microbiology , Adolescent , Adult , Child , Cryptococcus/isolation & purification , Enterobacteriaceae/isolation & purification , Female , Humans , Male , Pseudomonas/isolation & purification , Saccharomyces/isolation & purification , Stenotrophomonas maltophilia/isolation & purification , Tibet/epidemiology
15.
Hong Kong Med J ; 9(1): 31-7, 2003 Feb.
Article in English | MEDLINE | ID: mdl-12547954

ABSTRACT

OBJECTIVE: To review recent data on the nature and pathobiology of periodontal infections and to elaborate how periodontal infections might increase susceptibility to some important systemic diseases and conditions. DATA SOURCES: Medline literature search and websites of the American Academy of Periodontology and American Medical Association. STUDY SELECTION: Literature and data on periodontal diseases and their links to systemic diseases. DATA EXTRACTION: Review of relevant information and data. DATA SYNTHESIS: Periodontal diseases, including gingivitis and periodontitis, are among the most common infections of humans. They are induced by bacteria and bacterial products of dental plaque and are characterised by inflammatory destruction of tooth-supporting connective tissues and alveolar bone. A growing body of scientific evidence has shown that severe periodontitis may enhance susceptibility to certain important systemic diseases and conditions, for example, cardiovascular disease, diabetes mellitus, adverse pregnancy outcomes, and pulmonary infections. The clinical implications of the emerging specialty of periodontal medicine for dental and medical practitioners are postulated. CONCLUSIONS: Periodontal diseases may be risk factors for cardiovascular disease, diabetes mellitus, adverse pregnancy outcomes, and pulmonary infections. Dental and medical practitioners should be aware of the clinical implications of these inter-relationships and treat affected patients in collaboration for better oral and general health.


Subject(s)
Periodontal Diseases/complications , Cardiovascular Diseases/etiology , Diabetes Mellitus/etiology , Female , Humans , Lung Diseases/etiology , Periodontitis/complications , Pregnancy , Pregnancy Outcome
16.
J Clin Periodontol ; 29(7): 604-14, 2002 Jul.
Article in English | MEDLINE | ID: mdl-12354085

ABSTRACT

OBJECTIVES: To determine the effect of scaling and root planing (SRP) on the interrelations of subgingival periodontopathogens and both interleukin-8 (IL-8) and granulocyte elastase activity in gingival crevicular fluid (GCF), and to assess their relations to the short-term treatment response in management of chronic periodontitis. MATERIAL AND METHODS: GCF and subgingival plaque were collected from 16 subjects with untreated chronic periodontitis at baseline and 4 weeks after SRP. IL-8 levels were determined by ELISA. Granulocyte elastase activity was analyzed with a specific substrate, pGluProVal-pNA, and the maximal rate of elastase activity (MR-EA) was calculated. 5 DNA-probes were used to detect the presence of A. actinomycetemcomitans (A. a.), B. forsythus (B.f.), P. gingivalis (P.g.), P. intermedia (P.i.), and T. denticola (T.d.), with a sensitivity = 103 cells/paper point. RESULTS: IL-8 and MR-EA levels in GCF decreased significantly after SRP (p < 0.001) with a corresponding reduction of total count of the species. Of the sites with probing depth (PD) >/= 5.0 mm and co-infection by B.f., P.g., P.i. & T.d. at baseline, the sites without persistent co-infection of these species after SRP exhibited a significant reduction of IL-8 levels (p < 0.02), MR-EA levels (p < 0.02) and PD (p < 0.01). No such change was found in the sites where such a co-infection persisted. Moreover, reduction of IL-8 levels in those pocket sites was accompanied by a concomitant reduction of MR-EA (p < 0.02) and PD (p < 0.01), while no significant change in MR-EA levels and PD was noted in those pocket sites that exhibited an increase of IL-8 levels after SRP. At baseline, the former group of sites showed significantly higher IL-8 levels than the latter group of sites (p < 0.02). CONCLUSIONS: IL-8-related granulocyte elastase activity was related to the change in infection patterns of the target periodontopathogens following scaling and root planing. Varying initial IL-8 levels in GCF and a corresponding shifting change of granulocyte elastase activity in GCF may characterize the different short-term treatment responses.


Subject(s)
Gingival Crevicular Fluid/chemistry , Gram-Negative Bacteria/growth & development , Interleukin-8/analysis , Leukocyte Elastase/analysis , Periodontitis/therapy , Adult , Aggregatibacter actinomycetemcomitans/growth & development , Alveolar Bone Loss/therapy , Bacteroides/growth & development , Chronic Disease , Colony Count, Microbial , Dental Plaque/microbiology , Dental Scaling , Follow-Up Studies , Humans , Linear Models , Matched-Pair Analysis , Middle Aged , Periodontal Attachment Loss/therapy , Periodontal Pocket/therapy , Periodontitis/microbiology , Porphyromonas gingivalis/growth & development , Prevotella intermedia/growth & development , Root Planing , Statistics as Topic , Statistics, Nonparametric , Treponema/growth & development
17.
J Dent Res ; 80(5): 1453-8, 2001 May.
Article in English | MEDLINE | ID: mdl-11437219

ABSTRACT

Relatively limited information is available about the oral health in the Guangdong Province of Southern China, the closest neighbor to Hong Kong. The study intended to explore the oral health status, knowledge, attitudes, and dental care utilization in the Guangdong population as a basis for formulating strategies for oral health prevention and treatment. Through multi-stage stratified and quota-sampling, individuals from urban as well as rural communities were selected (5- to 6-; 12-; 35- to 44-; and 65- to 74-year-olds; total N = 6251). Structured interviews and clinical examinations were performed. Inter-examiner reliability was high (kappa = 0.60-0.96). Samples of community water were taken for fluoride assessment. Overall, the sample surveyed was acceptably representative of the population, with some under-representation of rural residents and agricultural workers. Re-weighting was performed in appropriate analyses. The data analysis model used in the Second International Collaborative Study was used as a guide for the present data analysis. This approach has not previously been used on a Mainland Chinese population.


Subject(s)
Dental Health Surveys , Oral Health , Adolescent , Adult , Aged , Child , Child, Preschool , China/epidemiology , DMF Index , Data Collection/methods , Demography , Dental Caries/epidemiology , Factor Analysis, Statistical , Female , Fluoridation , Health Knowledge, Attitudes, Practice , Humans , Interviews as Topic , Male , Oral Hygiene/statistics & numerical data , Patient Selection , Periodontal Diseases/epidemiology , Prevalence , Sampling Studies , Surveys and Questionnaires
18.
J Dent Res ; 80(5): 1480-5, 2001 May.
Article in English | MEDLINE | ID: mdl-11437224

ABSTRACT

Periodontal diseases remain a concern in adult populations, but there have been no systematic descriptions of periodontal conditions, which have included periodontal attachment loss, among Southern Chinese. The main aim of this report is to describe the periodontal conditions in adult Chinese and to investigate factors that may have influenced periodontal attachment loss. Subjects were recruited from urban and rural survey sites throughout Guangdong. In total, 1,572 35- to 44-year-old subjects and 1,286 65- to 74-year-old subjects completed a structured interview and underwent a periodontal examination, which included the Community Periodontal Index (CPI) and periodontal Attachment Loss (ALoss) recordings. Calculus was found as the highest CPI score in 61-68% of the 35- to 44-year-old subjects and in 54-57% of the 65- to 74-year-olds. Shallow pockets were found as the highest CPI score in about one-third of both the urban and the rural subjects in both age groups, and deep pockets in 3-7% of the subjects. ALoss was more prevalent than pockets in both age groups. On the basis of the ALoss recordings, about one-third of the subjects in both age groups were categorized as exhibiting considerable ALoss for their age. In both age groups, logistic regression analysis indicated that being male, wearing partial dentures, and reporting less frequent toothbrushing were found to be associated with considerable ALoss.


Subject(s)
Periodontal Diseases/epidemiology , Adult , Aged , Chi-Square Distribution , China/epidemiology , Denture, Partial/statistics & numerical data , Educational Status , Female , Health Behavior , Health Knowledge, Attitudes, Practice , Humans , Logistic Models , Male , Oral Hygiene/statistics & numerical data , Periodontal Attachment Loss/epidemiology , Periodontal Index , Risk Factors , Rural Health/statistics & numerical data , Socioeconomic Factors , Urban Health/statistics & numerical data
19.
J Dent Res ; 80(5): 1486-90, 2001 May.
Article in English | MEDLINE | ID: mdl-11437225

ABSTRACT

The objectives of this analysis were to determine the prevalence of oral mucosal lesions (OML) among adults in Southern China and to determine possible associations between OML and reported tobacco-smoking and alcohol-drinking habits. The sample consisted of 1,573 35- to 44-year-old and 1,515 65- to 74-year-old Chinese from both urban and rural areas of Guangdong Province. The subjects were interviewed by trained interviewers and underwent a clinical examination of the oral mucosa performed according to WHO guidelines. A specially prepared color atlas of OML was used for lesion recognition and confirmation during the survey. Among the 35- to 44-year-old subjects, the overall prevalence of OML was found to be 13% in urban men, 6% in urban women, 15% in rural men, and 4% in rural women. The corresponding figures for the 65- to 74-year-olds were 22%, 12%, 26%, and 19%. Tongue lesions and white lesions were relatively common, but denture-related lesions were not. No malignancies or erythroplakia was observed. Age and gender were found to relate to the occurrence of OML. In elderly men, smoking was significantly (p < 0.05) associated with some white lesions and tongue lesions, and alcohol drinking was also associated with some white lesions. In conclusion, tongue lesions and white lesions were relatively common in men, but pre-cancerous lesions were not prevalent.


Subject(s)
Mouth Diseases/epidemiology , Mouth Mucosa/pathology , Adult , Aged , Alcohol Drinking/epidemiology , China/epidemiology , Female , Humans , Interviews as Topic , Leukoplakia/epidemiology , Male , Mouth Neoplasms/epidemiology , Prevalence , Rural Health/statistics & numerical data , Smoking/epidemiology , Surveys and Questionnaires , Tongue, Fissured/epidemiology , Urban Health/statistics & numerical data
20.
J Dent Res ; 80(5): 1491-5, 2001 May.
Article in English | MEDLINE | ID: mdl-11437226

ABSTRACT

The objectives of this analysis were to describe the numbers of teeth lost and those indicated for extraction, dental prosthetic status, and occluding tooth pairs among adults in Southern China and to investigate factors affecting tooth mortality. A sample consisting of 1,573 35- to 44-year-old and 1,515 65- to 74-year-old urban and rural Chinese was examined clinically by calibrated examiners. Teeth not present for any reason were defined as missing (MT). The sum of MT and teeth indicated for extraction (IMT) was defined as adjusted missing teeth (AMT). Only 4.4% of the urban and 3.4% of the rural 65- to 74-year-olds were edentulous. MT were not significantly different between urban and rural residents, but more IMT were found in rural residents. Women, those who had a lower education level, and those who were less wealthy had more AMT in both age groups. Smoking was found to be associated with AMT in the 35- to 44-year-olds. Eighteen percent of the urban and 27% of the rural elderly had no occluding tooth pairs after IMT were accounted for, and only 38% and 30%, respectively, had 10 or more occluding pairs. Fifty-one percent of the urban and 43% of the rural elderly were found to have some form of dental prostheses in either jaw. A partial denture was more common in urban residents in both age groups.


Subject(s)
Tooth Loss/epidemiology , Adult , Aged , Analysis of Variance , China/epidemiology , Dental Occlusion , Denture, Partial/statistics & numerical data , Educational Status , Female , Humans , Male , Rural Health/statistics & numerical data , Sex Factors , Socioeconomic Factors , Tooth Extraction/statistics & numerical data , Urban Health/statistics & numerical data
SELECTION OF CITATIONS
SEARCH DETAIL
...