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2.
J Gerontol A Biol Sci Med Sci ; 53(1): B59-70, 1998 Jan.
Article in English | MEDLINE | ID: mdl-9467424

ABSTRACT

Declines in chronic disability were observed in the National Long Term Care Survey (NLTCS) 1982 to 1994. We analyzed the 1982, 1984, 1989, and 1994 NLTCS to identify the dimensions of chronic disability from multivariate analyses of a rich battery of measures of the ability (or inability) to perform specific activities. Changes over time in the prevalence of individual disability dimensions can be tracked to evaluate the rate of age-related losses of specific functions, 1982-1994. Seven dimensions described changes in the age dependence of 27 activities of daily living, instrumental activities of daily living, and physical performance measures in community and institutional resident elderly individuals over the 12 year period. Adjusted for age, the healthiest dimension with the best physical function experienced the largest increase in prevalence (3.3%) implying a decline in age-related disability. Disability declines were correlated with reductions in select health conditions (e.g., dementia and circulatory disease) over the study period.


Subject(s)
Aging , Disabled Persons/statistics & numerical data , Activities of Daily Living , Age Factors , Aged , Aged, 80 and over , Arteriosclerosis/epidemiology , Cerebrovascular Disorders/epidemiology , Chronic Disease/epidemiology , Dementia/epidemiology , Health Status , Humans , Institutionalization , Likelihood Functions , Longitudinal Studies , Multivariate Analysis , Musculoskeletal Diseases/epidemiology , Myocardial Infarction/epidemiology , Prevalence , Psychomotor Performance , United States/epidemiology , Vascular Diseases/epidemiology
4.
Stroke ; 27(8): 1310-5, 1996 Aug.
Article in English | MEDLINE | ID: mdl-8711793

ABSTRACT

BACKGROUND AND PURPOSE: We investigated apolipoprotein E polymorphism stroke risk in a population sample of 1810 persons aged 75 years or more in Stockholm (the Kungsholmen Project). Information on cognition at cohort inception (from 1987 to 1989) and on stroke occurrence (from 1969 to 1994) is available for the cohort. In the cohort, cognitive impairment is associated with the epsilon 4 allele, and longer survival in subjects aged > or = 85 years with good cognition is associated with the epsilon 2 allele and the absence of epsilon 4. METHODS: We compared stroke incidence in the 1077 of 1124 genotyped subjects who carried epsilon 2/3, epsilon 3/3, or epsilon 3/4 and estimated the proportion of cognitive impairment attributable to stroke. RESULTS: Risk of stroke did not vary with apolipoprotein E polymorphism (P = .82): 24% of 87 incident stroke patients during follow-up compared with 25% of 827 subjects with normal cognition and no stroke diagnosis at baseline carried the epsilon 3/4 genotype. An estimated 9% of cognitive impairment was attributable to stroke. Notably, a reduced epsilon 3/4 frequency of 20% was found in subjects who survived a prior stroke and were included in the cohort, and risk of hemorrhagic stroke tended to be associated with the presence of the epsilon 3/4 genotype and the absence of epsilon 2/3. CONCLUSIONS: This population-based study indicates that apolipoprotein E polymorphism is not a risk factor for ischemic stroke in subjects aged > or = 75 years (although it might possibly influence survival after stroke occurrence and be a risk factor for infrequent hemorrhagic stroke) and that approximately 10% of cognitive impairment in this age group is attributable to stroke.


Subject(s)
Apolipoproteins E/genetics , Cerebrovascular Disorders/genetics , Polymorphism, Genetic , Aged , Aged, 80 and over , Aging/genetics , Cerebral Hemorrhage/epidemiology , Cerebral Hemorrhage/genetics , Cerebrovascular Disorders/epidemiology , Cognition Disorders/epidemiology , Cognition Disorders/etiology , Cognition Disorders/genetics , Cohort Studies , Follow-Up Studies , Humans , Incidence , Risk Factors
5.
Arch Neurol ; 53(5): 418-22, 1996 May.
Article in English | MEDLINE | ID: mdl-8624216

ABSTRACT

OBJECTIVE: To quantify the influence of apolipoprotein E (APOE) polymorphism on cognition and survival in a population sample aged 75 years or older. DESIGN: The Kungsholmen Project established a cohort of 1810 residents in a district in Stockholm, Sweden, aged 75 years or older in 1987. Information on cognition at cohort inception is available for all subjects. Subjects were followed up for mortality to January 1, 1995. SUBJECTS: Included in this study are 1077 subjects (of 1124 genotyped for APOE) with the common epsilon 2/3, epsilon 3/3, and epsilon 3/4 APOE genotypes. RESULTS: The odds of cognitive impairment for the epsilon 3/4 vs epsilon 3/3 genotype declined with age: 4.8 for age 75 through 79 years; 1.7 for age 80 through 84 years; and 1.0 (i.e., no association) for age 85 years or older. Despite this association, APOE polymorphism did not significantly predict survival in subjects younger than 85 years, nor did it predict survival in subjects 85 years or older who were cognitively impaired. Instead, survival varied fourfold with respect to APOE polymorphism in those 85 years or older who had good cognition: Mortality in subjects with the epsilon 2/3 genotype was half that in those who carried the epsilon 3/3 genotype (hazard ratio, 0.5; 95% confidence interval, 0.2 to 0.9), and mortality in subjects with the epsilon 3/4 genotype was twice that in those who carried the epsilon 3/3 genotype (hazard ratio, 2.0; 95% confidence interval, 1.1 to 3.5). This fourfold variation resulted in 2-year differences in survival. CONCLUSIONS: The minor sequence variation in the apolipoprotein E isoforms resulted in a fourfold difference in the risk of death among the oldest old (age > or = 85 years) with good cognition. The observed variation in mortality was unlikely to have been caused by cognitive impairment, as APOE polymorphism was not a risk factor for cognitive impairment in this age group.


Subject(s)
Aged, 80 and over , Apolipoproteins E/genetics , Cognition , Mortality , Age Factors , Aged , Cohort Studies , Confidence Intervals , DNA/blood , DNA/isolation & purification , Female , Gene Frequency , Genotype , Humans , Leukocytes , Male , Middle Aged , Neuropsychological Tests , Predictive Value of Tests , Proportional Hazards Models , Risk Factors , Sex Factors , Survival Rate , Sweden
6.
J Clin Epidemiol ; 49(2): 173-82, 1996 Feb.
Article in English | MEDLINE | ID: mdl-8606318

ABSTRACT

We examined the use of proxies in samples of persons aged 65 years and over from the 1982 and 1984 National Long-Term Care Surveys (NLTCS). The NLTCS are designed to describe the Medicare-enrolled elderly population, their health and functioning, hospital, home health, and institutional use. The NLTCS, being longitudinal, allows trends in functional and health status to be examined as well as the changing character of community-based and institutional services used by chronically disabled persons aged 65 years and older. In analyses of proxy responses there was little evidence of differences in accuracy between self- and proxy reports in persons with different health and functional characteristics. The amount and type of proxy reporting did depend on the health and functional characteristics of the sample person. The cognitively impaired, and the frail elderly, had high levels of proxy use as well as small differences in the accuracy of reporting service use and program enrollment. The results are consistent with methodological studies of proxy reporting in health surveys of other populations.


Subject(s)
Geriatric Assessment , Health Services/statistics & numerical data , Health Status , Long-Term Care/statistics & numerical data , Surveys and Questionnaires/standards , Aged , Aged, 80 and over , Bias , Disabled Persons , Female , Health Surveys , Humans , Longitudinal Studies , Male , Medicare , Multivariate Analysis , Reproducibility of Results , United States
8.
J Gerontol ; 48(4): S153-66, 1993 Jul.
Article in English | MEDLINE | ID: mdl-8315240

ABSTRACT

The U.S. elderly (65+) and oldest-old (85+) populations are growing rapidly which, combined with their high per capita acute and long-term care needs, will increase total U.S. health care needs. Also important in determining needs is how health and function change as mortality declines in the elderly population. Recent increases in adult life expectancy have been due to declines in stroke and heart disease mortality. There is controversy, however, about how those declines relate to the health and function of survivors. We examined changes in the prevalence and incidence of chronic disability using the 1982, 1984, and 1989 National Long Term Care Surveys. The total prevalence of U.S. chronically disabled community-dwelling and institutionalized elderly populations declined from 1984 to 1989, overall, for each of three age strata and after mortality adjustment. These changes varied over level of disability. Factors contributing to these changes, including measurement, are reviewed.


Subject(s)
Disabled Persons/statistics & numerical data , Institutionalization/statistics & numerical data , Activities of Daily Living , Aged , Aged, 80 and over , Disabled Persons/classification , Humans , Incidence , Mortality , Prevalence , United States/epidemiology
9.
Natl Med Care Util Expend Surv B ; (13): 1-38, 1986 Dec.
Article in English | MEDLINE | ID: mdl-10304187

ABSTRACT

The goal of the National Medical Care Utilization and Expenditure Survey (NMCUES) is to improve the understanding of the ways in which Americans use and pay for health care. This report is one in a series of descriptive reports based on NMCUES data. Data concerning several aspects of insurance coverage were collected from household respondents in NMCUES. These data included the kind of insurance in effect for each person (Medicare, Medicaid, private, or other) and the use of inpatient and ambulatory health services. The purpose of this report is to provide descriptive information about the distribution of insurance coverage among the U.S. population and the use of inpatient and ambulatory services by people with different kinds of insurance. The results presented are based on data collected about the civilian noninstitutionalized persons in the NMCUES national household sample. In this report, "person-year" estimates for health insurance coverage are used; that is, individuals are assigned to different categories of insurance coverage according to the proportion of the year that they were covered by each kind of insurance. Although estimates are calculated as person-years of coverage, they are expressed as persons covered for convenience. Two important subpopulations--persons under 65 years of age and persons 65 years of age or over--are addressed separately because they have different patterns of insurance coverage and because utilization is so heavily influenced by age. Persons 65 years of age or over used significantly more inpatient and ambulatory services than persons under 65 years of age did. Only those in the younger group with Medicare, who were disabled, had utilization rates very similar to those of the aged. Persons under 65 years of age are classified by six mutually exclusive insurance categories: All Medicare. Medicaid, no private health insurance. Private health insurance, no Medicaid. Medicaid and private health insurance. Other coverage only. No insurance. Persons 65 years of age or over are classified by four mutually exclusive categories: Medicare only. Medicare and Medicaid. Medicare and private or other coverage. No Medicare. These categories of insurance coverage describe the kind of organization or program that supplies the coverage. With the exception of Medicare, which is a national program, these classifications provide little information about the scope of benefits and level of payment available to people who are covered. Considerable variation exists by State within the Medicaid category and by plan or program within the private insurance and other coverage categories.(ABSTRACT TRUNCATED AT 400 WORDS)


Subject(s)
Health Services/statistics & numerical data , Insurance, Health/statistics & numerical data , Age Factors , Aged , Ambulatory Care/statistics & numerical data , Centers for Medicare and Medicaid Services, U.S. , Data Collection , Hospitalization/statistics & numerical data , Hospitals/statistics & numerical data , Humans , Medicaid/statistics & numerical data , Medicare/statistics & numerical data , National Center for Health Statistics, U.S. , United States
10.
Natl Med Care Util Expend Surv B ; (5): 1-37, 1985 Aug.
Article in English | MEDLINE | ID: mdl-10304189

ABSTRACT

The goal of the National Medical Care Utilization and Expenditure Survey (NMCUES) of 1980 was to improve the understanding of the ways in which Americans use and pay for health care. This report is one in a series of descriptive reports based on NMCUES data. Data concerning insurance coverage were collected from household respondents in NMCUES. These data included the kind of insurance in effect for each person, the services covered, and the amounts paid by each source. In addition, the administration of private insurance plans and the kinds of charges covered were identified. The purpose of this report is to provide descriptive information about supplemental insurance coverage among the aged Medicare population with special emphasis on private supplemental health insurance coverage. For this report, supplemental insurance is defined as coverage (i.e., Medicaid, private, or other) in addition to Medicare and is to be distinguished from the Supplementary Medical Insurance part of Medicare that is known as SMI or Part B of Medicare. The results presented are based on data collected about the civilian, noninstitutionalized persons in the NMCUES national household sample who at any time during the survey year of 1980: (1) were 65 years of age or over, and (2) reported having been covered by Medicare Hospital Insurance (HI), or Medicare Supplementary Medical Insurance (SMI), or both. This report uses time-adjusted estimates that assign a single individual to different categories of insurance coverage according to the proportion of the year that he or she was covered by each kind of insurance. Consequently, estimates are made for person-years of coverage although they are expressed as persons for convenience. Approximately 4 out of 5 aged Medicare beneficiaries reported having some kind of insurance coverage in addition to Medicare during 1980. Approximately 67 percent of the aged Medicare population are estimated to have had private insurance in addition to Medicare; an estimated 13 percent had Medicaid. (Both of these estimates include 2.5 percent who reported Medicaid and private insurance simultaneously.) About 21 percent of the aged Medicare beneficiaries reported that Medicare was their only source of third-party coverage. The percentage of the aged Medicare beneficiaries who reported Medicare as their only source of third-party coverage was consistently 20 percent regardless of health status. However, the distribution among insurance categories of the remaining 80 percent who reported supplemental coverage of some type varied by health status. Medicare beneficiaries who were in poor health were much more likely to have Medicaid than Medicare beneficiaries who reported being in excellent health.(ABSTRACT TRUNCATED AT 400 WORDS)


Subject(s)
Deductibles and Coinsurance/statistics & numerical data , Insurance, Health/statistics & numerical data , Medicare/statistics & numerical data , Aged , Blue Cross Blue Shield Insurance Plans/statistics & numerical data , Centers for Medicare and Medicaid Services, U.S. , Data Collection , Group Practice, Prepaid/statistics & numerical data , Health Maintenance Organizations/statistics & numerical data , Humans , National Center for Health Statistics, U.S. , United States
11.
Natl Med Care Util Expend Surv B ; (3): 1-31, 1984 Apr.
Article in English | MEDLINE | ID: mdl-10304188

ABSTRACT

The goal of the National Medical Care Utilization and Expenditure Survey (NMCUES) is to improve the understanding of the ways in which Americans use and pay for health care. This report is one in a series of descriptive reports based on NMCUES data. Data concerning several aspects of participants' access to health care services were collected in NMCUES. These included identification of a regular source of care, several characteristics of physical access to the regular source (transportation mode, travel time, waiting room time), insurance coverage, and the existence of medically unattended conditions. The purpose of this report is to provide descriptive information about selected aspects of access to health care among noninstitutionalized elderly people who reported being covered by Medicare. The results presented are based on data collected about noninstitutionalized people in the NMCUES national household sample who: (1) were 65 years of age and over at any time during the survey year, and (2) reported being covered by Medicare Hospital Insurance, Supplementary Medical Insurance, or both during the survey year (1980). The regular source of care for three out of four (74 percent) of the elderly Medicare beneficiaries was a physician's office (including group practice or doctor's clinic), while for 9 percent the regular source was a hospital outpatient clinic, emergency room, health center, or other provider type (referred to hereafter as "clinic"). Of the elderly Medicare beneficiaries, 10 percent reported no regular source of care, and the regular source was unknown for 7 percent. Of those with no regular source of care, 80 percent identified their seldom getting sick as an important reason for having no regular source, 24 percent identified their desire to go to different places for different health care needs, 14 percent said their usual source was no longer available, and 5 percent identified their recently moving into the area as an important reason. Nearly six out of ten (59 percent) of the elderly Medicare beneficiaries who reported that their regular source was a physician's office drove themselves there, and about four out of ten (43 percent) of those who reported that their regular source was a clinic drove themselves to the clinic. On the average, people traveled nearly 10 minutes more to a clinic than to a physician's office (29 versus 20 minutes). There was little variability in reported length of travel time among the various demographic categories--e.g., men tended to travel for the same length of time as did women, black people for the same travel time as white people.(ABSTRACT TRUNCATED AT 400 WORDS)


Subject(s)
Health Services Accessibility/statistics & numerical data , Medicare/statistics & numerical data , Aged , Aged, 80 and over , Centers for Medicare and Medicaid Services, U.S. , Data Collection , Demography , Health Status , Humans , Insurance, Health/statistics & numerical data , National Center for Health Statistics, U.S. , Socioeconomic Factors , Transportation , United States
12.
Natl Med Care Util Expend Surv B ; (2): 1-24, 1983 Sep.
Article in English | MEDLINE | ID: mdl-10313517

ABSTRACT

The goal of the National Medical Care Utilization and Expenditure Survey (NMCUES) was to improve the understanding of the ways in which Americans use and pay for health care. This report is one in a series of descriptive reports based on NMCUES data. Data concerning several aspects of participants' health status were collected in NMCUES. These included measures of disability, activity limitation, illness conditions, and perceived health status. The purpose of this report is to provide preliminary descriptive information from NMCUES about selected aspects of the health status of noninstitutionalized elderly people who reported being covered by Medicare. The results presented are based on data collected about noninstitutionalized people in the NMCUES national household sample who: (1) were 65 years of age and over at any time during the survey year, and (2) reported being covered by Medicare Hospital Insurance, Supplementary Medical Insurance, or both during the survey year (1980). Of the aged Medicare beneficiaries, 37 percent reported experiencing no days on which their activities were limited for health reasons during the survey year. The average number of restricted activity days (RAD's) per year per person among all aged Medicare beneficiaries was estimated to be 31. By comparison, people under 65 years of age averaged 12 RAD's. At the beginning of the survey period, 60 percent reported that they were not limited in either their usual activity (e.g., work) or other activities (e.g., recreation) for health reasons. Men were substantially more likely than women to be limited in their activities (52 versus 31 percent). Of persons under 65 years of age, 94 percent reported no activity limitation. Of aged Medicare beneficiaries, 7 percent reported having no illness conditions during the survey year, while 23 percent reported seven or more illness conditions. Only 5 percent reported having one or more illness conditions for which they had not sought medical attention. The average number of conditions per person during the year was 4.4. People under 65 years of age averaged 2.9 illness conditions. The health of more than one-fourth (26 percent) of the elderly Medicare beneficiaries was judged to be excellent relative to other people of the same age, while the health of one out of eight people (12 percent) was judged to be poor.(ABSTRACT TRUNCATED AT 400 WORDS)


Subject(s)
Health Status , Medicare/statistics & numerical data , Activities of Daily Living , Age Factors , Aged , Data Collection , Educational Status , Female , Humans , Income/statistics & numerical data , Male , Morbidity , Self Concept , Sex Factors , United States/epidemiology
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