Biomechanical evaluation of pedicle screws versus pedicle and laminar hooks in the thoracic spine.

BACKGROUND CONTEXT: Pedicle screws have been shown to be superior to hooks in the lumbar spine, but few studies have addressed their use in the thoracic spine. PURPOSE: The objective of this study was to biomechanically evaluate the pullout strength of pedicle screws in the thoracic spine and compare them to laminar hooks. STUDY DESING/SETTING: Twelve vertebrae (T1-T12) were harvested from each of five embalmed human cadavers (n=60). The age of the donors averaged 83+8.5 years. After bone mineral density had been measured in the vertebrae (mean=0.47 g/cm(3)), spines were disarticulated. Some pedicles were damaged during disarticulation or preparation for testing, so that 100 out of a possible 120 pullout tests were performed. METHODS: Each vertebra was secured using a custom-made jig, and a posteriorly directed force was applied to either the screw or the claw. Constructs were ramped to failure at 3 mm/min using a Mini Bionix II materials testing machine (MTS, Eden Prairie, MN). RESULTS: Pedicle claws had an average pullout strength of 577 N, whereas the pullout strength of pedicle screws averaged 309 N. Hooks installed using the claw method in the thoracic spine had an overwhelming advantage in pullout strength versus pedicle screws. Even in extremely osteoporotic bone, the claw withstood 88% greater pullout load. CONCLUSION: The results of this study indicate that hooks should be considered when supplemental instrumentation is required in thoracic vertebrae, especially in osteoporotic bone.

Biomechanical evaluation of the pullout strength of cervical screws.

OBJECTIVE: In the process of anterior cervical fusion, little is known about the biomechanics of anterior cervical screw pullout. In this study, three different aspects of cervical screw fixation were evaluated: self-tapping (ST) versus self-drilling (SD) screws, the effect of screw geometry (length, diameter, thread pitch), and the use of rescue screws. METHODS: Nine screws consisting of different diameters, lengths, and thread pitch (cancellous and cortical) were tested in peak pullout force in an artificial bone model using an MTS 858 Mini Bionix test system. Rescue screws (4.5 mm) were then inserted in the failed holes of 4.0-mm screws and extracted to determine their holding strength. RESULTS: Length of screws and thread pitch both had a significant effect on the pullout force. Each 1 mm of increased screw length translates to 16 N of increased force to pullout in the foam bone model. Pullout strength did not vary significantly according to screw diameter or between SD and ST screws. However, the SD screw has an advantage because it can decrease the length of surgery. A decrease in pullout force of between 43% and 70% was found when using rescue screws. CONCLUSIONS: In situations in which the use of rescue/salvage screws is required, the surgeon should anticipate a significant decrease in the holding force compared with the original screw. Future directions for research include an evaluation of pullout force for screw and plate constructs.

Risk factors for pulmonary emboli after total hip or knee arthroplasty.

Because it is difficult to predict which patients may sustain a pulmonary embolism after total hip or knee arthroplasty, we assessed multiple thrombophilic and hypofibrinolytic parameters to identify risk factors. Twenty-nine patients who survived a known pulmonary embolism after total knee or total hip arthroplasty were matched by age, gender, race, arthritic diagnosis, procedure, and surgery date with 29 patient-controls who had a total hip or knee arthroplasty but who did not have a symptomatic known pulmonary embolism or deep vein thrombosis. Twenty-one serologic measures and five genes associated with thrombophilia, hypofibrinolysis, or both were assessed without knowledge of group assignment. All patients with pulmonary embolism had at least one abnormality of plasminogen activator inhibitor activity, dilute Russell's viper venom time, prothrombin time, or total cholesterol versus 13 of 27 (48%) control patients. Forty-seven percent of patients who experienced pulmonary embolism had at least two abnormalities of plasminogen activator inhibitor activity, dilute Russell's viper venom time, prothrombin time, or total cholesterol, versus 7% of control patients. Preoperatively, to identify patients at high risk of pulmonary embolism, plasminogen activator inhibitor activity, dilute Russell's viper venom time, prothrombin time, and cholesterol levels were most predictive. Using at least one abnormality of these four measures as a screening test to detect risk of pulmonary embolism, the test is sensitive (100%), and the predictive value of a negative test is high (100%). After additional prospective study, this may allow identification of patients at low risk (the majority of patients) in whom anticoagulation may not be required and a small group of patients at high risk for pulmonary embolism in whom prophylactic anticoagulation should be provided.

Load sharing in Premier and Zephir anterior cervical plates.

STUDY DESIGN: An in vitro biomechanical study using a simulated anterior cervical discectomy and interbody fusion model to compare the load sharing properties of two semiconstrained cervical (Premier and Zephir) plates. OBJECTIVES: To determine the percent load transmission through these plates and grafts under simple axial compression. SUMMARY OF BACKGROUND DATA: No published data exist as to the load transmission through these semiconstrained plates. METHODS: Cadaveric calf spines were subjected to axial compression loading while instrumented with an interbody graft and with the graft plus one of the plates. Load transmission was computed through an analysis of the load-displacement data. RESULTS: A mean load transmission of 23% was shared by the Premier plate. The Zephir, a more constrained plate but still semiconstrained, shared a mean of 32% of the load. CONCLUSIONS: The semiconstrained plates tested allow more graft loading than some previously tested constrained plates. However, there are differences between the research methods used in these studies that provide a less than satisfactory comparison.