ABSTRACT
Paraguay is currently facing a new outbreak of Chikungunya virus. This report summarizes two severe cases of Chikungunya (CHIKV) infection, confirmed by real-time reverse transcription polymerase chain reaction. We present the cases of patients with acute CHIKV infection and multisystem involvement, with fever, rash, abdominal pain, vomiting, myocarditis, and coronary artery anomalies, very similar to the cases described in MIS-C related to SARS-CoV-2 during the COVID-19 Pandemic. Both patients received IVIG and methylprednisolone, with good clinical response. In this setting of cytokine storm in Chikungunya, can we call it Multisystem inflammatory syndrome associated with Chikungunya?.(AU)
Paraguay se enfrenta actualmente a un nuevo brote del virus Chikungunya. Este informe resume dos casos graves de infección por Chikungunya (CHIKV), confirmados mediante reacción en cadena de la polimerasa con transcripción inversa en tiempo real. Presentamos los casos de pacientes con infección aguda por CHIKV y afectación multisistémica, con fiebre, erupción cutánea, dolor abdominal, vómitos, miocarditis y anomalías de las arterias coronarias, muy similares a los casos descritos en síndrome inflamatorio multisistémico relacionado con el SARS-CoV-2 durante la pandemia de COVID-19. Ambos pacientes recibieron IGIV y metilprednisolona, con buena respuesta clínica. En este escenario de tormenta de citoquinas en Chikungunya, ¿podemos llamarla «síndrome inflamatorio multisistémico asociado a Chikungunya»?.(AU)
Subject(s)
Humans , Male , Female , Infant, Newborn , Child , Cytokines , Chikungunya Fever , Chikungunya virus , /epidemiology , Paraguay , Inpatients , Physical ExaminationABSTRACT
Paraguay is currently facing a new outbreak of Chikungunya virus. This report summarizes two severe cases of Chikungunya (CHIKV) infection, confirmed by real-time reverse transcription polymerase chain reaction. We present the cases of patients with acute CHIKV infection and multisystem involvement, with fever, rash, abdominal pain, vomiting, myocarditis, and coronary artery anomalies, very similar to the cases described in MIS-C related to SARS-CoV-2 during the COVID-19 Pandemic. Both patients received IVIG and methylprednisolone, with good clinical response. In this setting of cytokine storm in Chikungunya, can we call it "Multisystem inflammatory syndrome associated with Chikungunya"?.
Subject(s)
Chikungunya Fever , Cytokine Release Syndrome , Systemic Inflammatory Response Syndrome , Humans , Chikungunya Fever/complications , Chikungunya Fever/diagnosis , Systemic Inflammatory Response Syndrome/diagnosis , Male , Cytokine Release Syndrome/etiology , Female , Adult , Middle AgedABSTRACT
Existen dos puntos de vista: Uno que según las normas se demuestra que existen falencias que impiden la calidad de atención en los servicios evaluados y otro que el usuario está satisfecho con la atención aunque no se cumplen con algunos requisitos para la calidad
