ABSTRACT
El síndrome de Morris o síndrome de insensibilidad completa a los andrógenos es la forma más común de seudohermafroditismo masculino. Los pacientes que portan esta patología son genéticamente masculinos con cariotipo 46XY, pero fenotípicamente femeninos, sin ambigüedad sexual. El riesgo de malignización testicular, lleva a un diagnóstico oportuno y temprano para su resolución quirúrgica. Se reporta el caso de una paciente de 17 años que consultó por amenorrea primaria en nuestro hospital.
Subject(s)
Amenorrhea , Androgen-Insensitivity Syndrome , Disorders of Sex DevelopmentABSTRACT
OBJECTIVE: To compare the bacteriological and clinical efficacy of three treatments for uncomplicated cystitis in ambulatory pre-menopausal women: ciprofloxacin 250 mg orally twice daily for 3 days, trimethoprim/sulfamethoxazole 160/800 mg orally twice daily for 7 days, and norfloxacin 400 mg orally twice daily for 7 days. MATERIALS AND METHODS: A total of 455 women were randomly assigned to three treatment groups: 151 received ciprofloxacin, 150 received trimethoprim/sulfamethoxazole, and 154 received norfloxacin. Bacteriological cure and clinical resolution were evaluated 5-9 days and 4-6 weeks after completion of treatment. RESULTS: There was no significant difference among the three treatment groups: overall efficacy ranged from 78.5% for the trimethoprim/sulfamethoxazole group, to 84.5% for the ciprofloxacin group. The highest overall incidence of drug-related adverse effects occurred in the trimethoprim/sulfamethoxazole patients. CONCLUSIONS: These data indicate that a 3 day treatment with ciprofloxacin is at least as clinically and bacteriologically effective as 7 day treatments with trimethoprim/sulfamethoxazole and norfloxacin for uncomplicated lower urinary tract infections.
