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Paediatr Anaesth ; 29(10): 1060-1061, 2019 10.
Article in English | MEDLINE | ID: mdl-31433900

ABSTRACT

While respiratory depression is a known complication of morphine overdose, the neuro-excitatory side effect of the morphine metabolite morphine-3-glucuronide is less widely known. Here, we report the case of an infant with neurological excitation after morphine overdose. The neuro-excitation in this infant was probably induced by an elevated morphine-3-glucuronide concentration.


Subject(s)
Analgesics, Opioid/adverse effects , Morphine Derivatives/adverse effects , Morphine/adverse effects , Morphine/metabolism , Respiratory Insufficiency/chemically induced , Drug Overdose , Humans , Infant , Male
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