The Role of Transesophageal Echocardiogram in the Diagnosis and Treatment of Intracardiac Tumors: A Case of Atrial Myxoma.

Cardiac myxoma is the most common primary heart tumor in adults. Although biologically benign, they can be life-threatening by obstructing heart function. They typically develop in the left atrium and can be polypoid (causing more obstruction) or papillary (more likely to cause embolizations). Symptoms are nonspecific, and diagnosis is relatively rare. Echocardiography is essential for quick diagnosis, and surgical removal is the primary treatment with low mortality rates, excellent postoperative survival, and low recurrence rates. We report a 73-year-old woman presented to the emergency room with extreme fatigue and weight loss. Further investigations revealed a mass in the left atrium suggestive of an intracardiac tumor on a thoracic computer tomography scan. A subsequent transesophageal echocardiogram was performed, which showed a large, mobile, and friable hyperechogenic intra-auricular mass adhered to the atrial septum with moderate mitral regurgitation and moderate aortic stenosis. This case highlights the crucial role that the transesophageal echocardiogram plays in these patients by accelerating diagnosis, assisting with myxoma resolution, and confirming the complete removal of the myxoma.

An Unusual Case of Vasospastic Angina Resulting in Multiple Episodes of Cardiac Arrest.

Coronary vasospasm is a well-recognized cause of angina (also known as Prinzmetal angina) and a common cause of admissions to the emergency department and coronary intensive care units. It is however an uncommon cause of cardiac arrest. We describe a patient with multiple episodes of chest pain followed by cardiac arrest in pulseless electrical activity (PEA) due to coronary vasospasm. Telemetry and electrocardiography showed ST-segment elevation followed by PEA. Each event was short-lived and resolved after a maximum of six minutes of advanced life support measures. The patient was started on treatment with a dihydropyridine calcium channel blocker (CCB) and nitroglycerin patch with no further episodes recorded to date.

Sequential Organ Failure Assessment Score in the ICU As a Predictor of Long-Term Survival After Cardiac Surgery.

OBJECTIVES: The Sequential Organ Failure Assessment (SOFA) score is a predictor of mortality in ICU patients. Although it is widely used and has been validated as a reliable and independent predictor of mortality and morbidity in cardiac ICU, few studies correlate early postoperative SOFA with long-term survival. DESIGN: Retrospective observational cohort study. SETTING: Tertiary academic cardiac surgery ICU. PATIENTS: One-thousand three-hundred seventy-nine patients submitted to cardiac surgery. INTERVENTIONS: SOFA 24 hours, SOFA 48 hours, mean, and highest SOFA scores were correlated with survival at 12 and 24 months. Wilcoxon tests were used to analyze differences in variables. Multivariate logistic regressions and likelihood ratio test were used to access the predictive modeling. Receiver operating characteristic curves were used to assess accuracy of the variables in separating survivor from nonsurvivors. MEASUREMENTS AND MAIN RESULTS: Lower SOFA scores have better survival rates at 12 and 24 months. Highest SOFA and SOFA at 48 hours showed to be better predictors of outcome and to have higher accuracy in distinguishing survivors from nonsurvivors than initial SOFA and mean SOFA. A decreasing score during the first 48 hours had mortality rates of 4.9%, while an unchanged or increased score was associated with a mortality rate of 5.7%. CONCLUSIONS: SOFA score in the ICU after cardiac surgery correlated with survival at 12 and 24 months. Patients with lower SOFA scores had higher survival rates. Differences in survival at 12 months were better correlated with the absolute value at 48 hours than with its variation. SOFA score may be useful to predict long-term outcomes and to stratify patients with higher probability of mortality.

Mitral Valve Infective Endocarditis Complicated With Coronary Artery Embolization.

Infective endocarditis is a multisystem and potentially fatal disease. Systemic embolization is a relatively common complication, the spleen and central nervous system being the most frequent sites for septic emboli formation. Coronary artery septic embolization is extremely uncommon and its management remains controversial. We present the case of a 50-year-old male diagnosed with mitral valve infective endocarditis complicated with spleen and central nervous system embolization, who developed acute myocardial infarction two weeks after disease onset. The patient was successfully treated with combined mitral valve replacement and coronary artery bypass grafting.

An Incident of a Massive Pulmonary Embolism Following Acute Aortic Dissection. a Case Report.

Acute aortic dissection and acute pulmonary embolism are two life-threatening emergencies. The presented case is of an 81-year-old man who has been diagnosed with an acute Stanford type A aortic dissection and referred to a tertiary hospital for surgical treatment. After a successful aortic repair and an overall favourable postoperative recovery, he was diagnosed with cervical and upper extremity deep vein thrombosis and was anticoagulated accordingly. He later presented with massive bilateral pulmonary embolism.

CARDIOGENIC SHOCK DUE TO VENTRICULAR SEPTAL DEFECT (VSD) AFTER MYOCARDIAL INFARCTION.

62 year-old man admitted in ICU post myocardial infarction with ventricular septal defect (VSD) and cardiogenic shock due to anterior descending artery stenosis. VSD corrected percutaneously after intra-aortic Figure 1 Transthoracic echocardiography with Doppler showing VSD after myocardial infarction due to anterior descendent stenosis. balloon pump insertion, resulting in iatrogenic tricuspid regurgitation. Tricuspid valvuloplasty, VSD correction and CABG performed after patient stabilization. Discharge after 26 days.

ECMELLA: successful rescue cardiopulmonary support in post-coronary artery bypass graft cardiogenic shock with cardiac arrest-case report.

BACKGROUND: Cardiogenic shock is the main cause of death in hospitalized patients with acute coronary syndromes, with a high mortality rate. The management of graft thrombosis after coronary artery bypass graft (CABG) surgery is challenging and the best revascularization strategy is not well defined. In patients who develop cardiac arrest due to graft thrombosis, the benefits of mechanical support during advanced cardiac life support are uncertain. Rescue extracorporeal cardiac bypass resuscitation has been used in the context of cardiopulmonary arrest, with survival rates of around 34.7% of which 28.5% with good neurological outcome. CASE SUMMARY: We present here the case of a patient who developed cardiogenic shock after CABG graft occlusion. The patient suffered refractory cardiac arrest during percutaneous revascularization and received rescue cardiopulmonary support. Revascularization was achieved and there was a successful resuscitation with the placement of venous-arterial extracorporeal membrane oxygenation (VA-ECMO) and an Impella CP device. After a 29-day hospitalization the patient was discharged with no neurological sequelae. DISCUSSION: Although there is limited evidence of the benefit of a combined use of mechanical support (VA-ECMO with other mechanical devices) in the management of cardiogenic shock and cardiac arrest following CABG surgery, there seems to be a lower mortality with this approach, and possibly more favourable neurological outcomes. Further research is needed to elucidate the advantages of Impella vs. intra-aortic balloon pump combined with VA-ECMO in such patients.

[Results of the utilization of the ECMO-VA following cardiac surgery, in the Department of Cardiothoracic Surgery of Santa Maria Hospital]. / Resultados Da Utilização Da Ecmo-va Em Doentes Pós Cirurgia Cardíaca No departamento De Cirurgia Cardiotorácica Do Hospital De Santa Maria.

OBJECTIVES: Extracorporeal membrane oxygenation through a veno-arterial circuit (ECMO-VA) is an organ support option in refractory cardiogenic shock, when the primary cause of decompensation is thought to be reversible. We report the clinical results of this technique in patients submitted to cardiac surgery at our center. METHODS: We present a retrospective study of patients that underwent ECMO-VA after cardiac surgery and subsequent admission at the intensive care unit (ICU), in our center. The data were collected from clinical records. The statistical analysis was made with an SPSS 22.0 data base. RESULTS: We report data on 7 patients with an average age of 62 years. The mean SAPS II was 56 points, the Euroscore II was 17% and the British Columbia Cardiac Surgery Intensive Care Score was 71%. 57% of patiens underwent myocardial revascularization surgery, 29% were submitted to valvular surgery and 14% of the patients underwent an aortic surgery. All of the patients underwent peripheral cannulation, 71% of which was placed during surgery and in the remaining 29%, immediately after. All of the patients were put on mechanical ventilation and 86% needed an intra-aortic baloon and renal support. The main complications were acute renal injury (100%), coagulopathy (86%), emergency re-sternothomy (43%) ischaemia of the cannulated limb (29%) and central nervous system complications (29%). The average time of ECMO-VA use was 5 days and the mean stay in the ICU was 19 days. In 57% of patients, the de-cannulation was successful. The average in-patient survival was 43%. CONCLUSION: Extracorporeal membrane oxygenation through a veno-arterial circuit (ECMO-VA) is an organ support option in refractory cardiogenic shock, when the primary cause of decompensation is thought to be reversible. The timely utilization of the procedure is crucial in cases with high probability of reversible causes of cardiogenic shock, where the rational for its use is to allow time for the myocardium to recover. The main difficulty identified for the procedure was the selection of patients that would benefit from this organ support, since there are no clear guidelines in the literature for its application. In our center, we obtained a survival rate of 43%, in line with values from international centers which report a survival rate between 20-40%. The use off this tool is indispensable for a center of cardiothoracic surgery. Without this technique, the surviving patients would present a high rate of mortality and consequently our surgical work would be frustrating.

[The transoesophageal echocardiography in the general intensive care: its utility in the ventilated critically ill patient]. / A ecocardiografia transesofágica nos cuidados intensivos polivalentes: a sua utilidade no doente crítico ventilado.

The use of the transoesophageal echocardiography (TEE) in the critically ill patient admitted to the general intensive care unit begins to turn out to be very important but it is still little spread. The full implementation of the echocardiography in the general intensive cares is compromised by the acoustic window. However, TEE can flyover this difficulty adding to the advantages widely described of the transthoracic echocardiography (TTE) other high values 1. The TEE manages to do the dynamic evaluation of the necessity of fluids, able to discriminate fluid responders, able to distinguish types of shock, assess systolic and diastolic function of both ventricles, able to evaluate other structures of the heart and be a guide to therapy. The use of the echocardiography in the ventilated patient admitted to the general intensive care unit still lack for some definition. This clinical commentary was carried out by the intention of revising the most relevant literature that values the use and efficiency of the TEE in the ventilated critically ill patient in order to explain its use and consequently helping to implement the TEE in clinical practice. So, one managed to define the application of the TEE in the critically ill patient in several clinical scenarios, the haemodynamically unstable patient, the patient with global respiratory insufficiency, the patient with hipoxémia.

Echocardiography by the non-cardiologist: a curriculum for the fast track strategy.

A formal echocardiographic approach in a general intensive care unit requires a 24 hour availability of an expert in echocardiography, who could not be easily found. Therefore, a goal-directed echocardiogram strategy specifically tailored to the intensivist should be created. The concept of goal-directed echocardiography (GDE) has been incompletely evaluated and it is necessary to find a curriculum program to grant proficiency. We propose the Fast-Track Echocardiographic Strategy (FTES) program to accomplish both objectives. All medical associations of echocardiography agree that extensive training and experience are needed to acquire and interpret a formal echocardiogram, however, to answer the five questions of FTES a simpler curriculum program would be enough. The aim of this review study was to propose a curriculum to teach non-cardiologist physicians intensivist (NCPI) to use a GDE such as FTES. A search for published literature, from 1999 until June 2008, in English and French languages in Medline was undertaken in order to find out the most relevant and contemporary studies in this area. Strength of evidence of the articles found was based on five strengths of evidence. A framework for published medical research's critical appraisal and a checklist for sources of bias were used for assessment of studies quality. In overall, all studies showed it was possible to teach NCPI to use a GDE examination. After a critical appraisal of the literature, we proposed FTES program to grant proficiency to NCPI in a GDE, to be used in hemodynamic unstable critically ill patients (hypotension with or without hypoxemia), to answer five simple questions, in order to define an hemodynamic profile and consequently be able to optimize their treatments. In conclusion, probably FTES program should at least be considered.