ABSTRACT
Squamous cell carcinoma of the breast is an extremely rare neoplasm. Approximately 50 cases have been reported in the English literature since 1917. The pathogenesis of squamous cell carcinoma of the breast is puzzling because epithelial elements are not normally identified in breast tissue. It has been suggested that epithelial cells are derived from epidermoid cysts deposited during early embryological development, from metaplastic transformation of ductal cells, or after trauma or surgical manipulation. Although no evidence has been published to support a casual relationship between liquid silicone-induced mastopathy and breast carcinoma, squamous cell cancers are known to arise in the setting of prolonged inflammation often seen after liquid silicone injection. This case of primary squamous cell carcinoma of the breast, arising 25 years after augmentation with liquid silicone injections, occurred in a 70-year-old patient with silicone-induced mastopathy.
Subject(s)
Breast Neoplasms , Carcinoma, Squamous Cell , Mammaplasty , Postoperative Complications , Aged , Breast Neoplasms/pathology , Carcinoma, Squamous Cell/pathology , Female , Humans , Magnetic Resonance Imaging , Silicone Elastomers , Time FactorsABSTRACT
The authors describe a case of Meckel's stones demonstrated by barium study of the small bowel. Preoperative diagnosis of Meckel's stones is extremely rare; but with knowledge of their existence, more cases should be encountered.
Subject(s)
Calculi/diagnostic imaging , Adult , Barium Sulfate , Calculi/complications , Calculi/etiology , Enema , Humans , Male , RadiographyABSTRACT
The incidence of malignancy of the anus is rare when compared to colorectal cancer. At The New York Hospital-Cornell Medical Center 43 patients with anal cancer were seen since 1932. Five-year survival for patients treated by local excision, abdominal-perineal resecion, and abdominal perineal resection with associated inguinofemoral groin node dissection was 43%, 66%, and 33%, respectively. Therapy should be guided by location, size, and depth of the local lesion, as well as clinical node status. In general, local excision should be reserved for the most minute lesion. Groin dissection should be carried out when nodes are clinically diseased.
Subject(s)
Anus Neoplasms/surgery , Carcinoma, Squamous Cell/surgery , Humans , Lymphatic Metastasis , Neoplasm Recurrence, LocalABSTRACT
Of 142 female patients over age 75 at The New York Hospital-Cornell Medical Center, 58 underwent radical mastectomy and 40 simple mastectomy for primary breast cancer. After five years, 19 per cent of the radical mastectomy group were cancer-free compared with 35 per cent of the simple mastectomy group. The gross five-year survival rates were 50 per cent and 47 per cent respectively. In the radical mastectomy group, when the axillary nodes did not show cancer at the time of operation, there have been no known recurrences and 70 per cent of the patients have survived at least five years. There was no surgical mortality. These findings support the view that until more controlled data are available, radical mastectomy is still the preferred therapy for primary breast cancer.
