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1.
BMJ Case Rep ; 17(5)2024 May 15.
Article in English | MEDLINE | ID: mdl-38749528

ABSTRACT

Scimitar syndrome is characterised by right lung hypoplasia and abnormal pulmonary venous return, known as the 'scimitar vein'. We report the case of an infant girl with scimitar syndrome who developed a severe respiratory distress mimicking asthma. Pulmonary hypertension (PH) was diagnosed, attributed to scimitar vein stenosis and a left-to-right shunt. Scimitar vein stenosis, a rare complication of scimitar syndrome, can lead to severe PH, highlighting the importance of prompt management in specialised care centres.


Subject(s)
Scimitar Syndrome , Humans , Scimitar Syndrome/diagnostic imaging , Scimitar Syndrome/complications , Scimitar Syndrome/diagnosis , Female , Infant , Constriction, Pathologic , Hypertension, Pulmonary/etiology , Hypertension, Pulmonary/diagnosis , Diagnosis, Differential , Pulmonary Veins/abnormalities , Pulmonary Veins/diagnostic imaging , Stenosis, Pulmonary Vein/diagnostic imaging , Stenosis, Pulmonary Vein/diagnosis
2.
BMJ Case Rep ; 17(2)2024 Feb 20.
Article in English | MEDLINE | ID: mdl-38378592

ABSTRACT

Tuberculosis (TB) poses a major global health threat, substantially affecting children, who contribute notably to new cases and deaths. Diagnosing TB in kids is challenging due to collection issues and the paucibacillary nature of the disease. Disseminated TB, uncommon in children in low TB incidence countries, remains a significant cause of morbidity in migrant populations. We illustrate a rare case of disseminated TB in a middle-childhood boy who migrated from Angola to France, displaying chronic cough, fatigue, weight loss and persistent fever. Investigations revealed widespread TB affecting several organs (lungs, heart, bones and lymph nodes). Prompt diagnosis led to a treatment regimen of four antibiotics (isoniazid, rifampin, pyrazinamide, ethambutol) and corticosteroids, resulting in substantial improvement after 2 months. Subsequent treatment involved two antibiotics (isoniazid and rifampin) for 10 more months. This case underscores the criticality of early identification and comprehensive treatment for disseminated TB, ensuring improved outcomes and reduced risks.


Subject(s)
Transients and Migrants , Tuberculosis, Miliary , Male , Humans , Child , Rifampin/therapeutic use , Isoniazid , Ethambutol , Pyrazinamide , Anti-Bacterial Agents , Tuberculosis, Miliary/drug therapy , Antitubercular Agents/therapeutic use
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