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Oxidation of guanine nucleosides to 4-amidinocarbamoyl-5-hydroxyimidazoles by dimethyldioxirane.
Davies, R Jeremy H; Stevenson, Clarke; Kumar, Shiv; Lyle, Jason; Cosby, Lisa; Malone, John F; Boyd, Derek R; Sharma, Narain D; Hunter, Ann P; Stein, Bridget K.
Nucleosides Nucleotides Nucleic Acids ; 22(5-8): 1355-7, 2003.
Article in English | MEDLINE | ID: mdl-14565417

ABSTRACT

Final oxidation products generated from guanosine and 2'-deoxyguanosine by reaction with dimethyldioxirane have been identified as 4-amidinocarbamoyl-5-hydroxyimidazoles.


Subject(s)
Deoxyguanosine/chemistry , Guanosine/chemistry , Amidines , Epoxy Compounds , Imidazoles , Indicators and Reagents , Oxidation-Reduction
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