1.
Mini Rev Med Chem
; 8(13): 1384-94, 2008 Nov.
Article
in English
| MEDLINE
| ID: mdl-18991754
ABSTRACT
Suramin is a polysulfonated polyaromatic symmetrical urea. It is currently used to treat African river blindness and African sleeping sickness. Suramin has also been extensively trialed recently to treat a number of other diseases, including many cancers. Here, we examine its modes of action and discuss its structure-activity relationships.