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Nat Prod Commun ; 11(3): 417-8, 2016 Mar.
Article in English | MEDLINE | ID: mdl-27169195

ABSTRACT

The essential oil obtained by hydrodistillation from the fresh fruits of Xylopia laevigata was analyzed by gas chromatography using a flame ionization detector (GC-FID) coupled to a mass spectrometer (GC-MS). Monoterpenes predominated, forming 95.0% of the total essential oil. The major constituents identified were limonene (56.2%), α-pinene (28.0%), and ß-pinene (5.5%). Cytotoxic activity against tumor cell lines and non-tumor cells was also investigated; however, neither the essential oil nor its major constituents evaluated presented any cytotoxic activity (IC50 > 25.0 µg mL⁻¹).


Subject(s)
Antineoplastic Agents, Phytogenic/chemistry , Antineoplastic Agents, Phytogenic/pharmacology , Fruit/chemistry , Oils, Volatile/pharmacology , Plant Oils/pharmacology , Xylopia/chemistry , Cell Line, Tumor , Humans , Oils, Volatile/chemistry , Plant Oils/chemistry
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