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Sci Rep ; 13(1): 10325, 2023 06 26.
Article in English | MEDLINE | ID: mdl-37365232

ABSTRACT

This prospective cohort longitudinal study examines the risk factors associated with different intrauterine environments and the influence of different intrauterine environments on children's motor development at 3- and 6-months of life. Participants were 346 mother/newborn dyads enrolled in the first 24 to 48 h after delivery in public hospitals. Four groups with no concurrent condition composed the sample: mothers with a clinical diagnosis of diabetes, mothers with newborns small for gestational age due to idiopathic intrauterine growth restriction (IUGR), mothers who smoked tobacco during gestation, and a control group composed of mothers without clinical condition. Children were assessed at three- and six-months regarding motor development, weight, length, head circumference, and parents completed a socioeconomic questionnaire. The IUGR children had lower supine, sitting, and overall gross motor scores at 6 months than the other children's groups. Anthropometric and sociodemographic characteristics negatively influenced gross motor development. IUGR and anthropometric and sociodemographic characteristics negatively impact motor development. Intrauterine environment impact child neurodevelopment.


Subject(s)
Fetal Growth Retardation , Mothers , Female , Infant, Newborn , Humans , Child , Infant , Longitudinal Studies , Prospective Studies , Fetal Growth Retardation/epidemiology , Fetal Growth Retardation/etiology , Birth Weight
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