ABSTRACT
Guinea-Bissau has particularly alarming indicators of maternal health, with one of the highest maternal mortality (MM) worldwide. According to UNICEF-2014, this ratio (MMR) was 900/100,000 live births, mostly due to preventable and treatable causes. In 2013, the European Union developed an Integrated Programme to reduce Maternal and Infant Mortality (EU/PIMI),** the largest project of this kind, implemented in Guinea-Bissau. This study performed a national audit of MM over 2020, with the aim to analyse its numbers, characteristics, and causes. We used data of local and regional hospitals where EU/PIMI-II was operating. These hospitals showed lower MMR than previous national figures; however, the exclusion of the main obstetrical referral hospitals, and the unknown number of community-based deliveries make it difficult to compare. Guinea-Bissau still faces enormous challenges in reducing MM. Despite the slow progresses, this study gives us hope, as EU/PIMI-IÍs interventions appeared to have a positive impact in MM reduction.
Subject(s)
Infant Mortality , Maternal Mortality , Infant , Humans , Guinea-Bissau/epidemiology , Retrospective Studies , Hospitals , FemaleABSTRACT
El síndrome de Russel-Silver es un cuadro polimalformativo que presenta como características más significativas la existencia de retraso de crecimiento prenatal y/o posnatal, una facies típica y asimetría corporal. El caso clínico que se describe corresponde a un lactante varón de 9 meses de edad, sin antecedentes familiares de interés, que en el momento del nacimiento presenta una somatometría adecuada a la edad gestacional (peso y estatura en el P25-50), y macrocefalia relativa debido a desproporción craneofacial. En la exploración se observa una cara pequeña de aspecto triangular, frente prominente, escleróticas azules, labios finos, comisuras bucales dirigidas hacia abajo, retromicrognatia, clinodactilia del quinto dedo de ambas manos y asimetría en la longitud y perímetro de las 4 extremidades con crecimiento a favor del brazo derecho y la pierna izquierda. Desde el nacimiento presentó retraso de crecimiento (peso y talla inferior al P5), y el perímetro cefálico se mantuvo en el P90. El desarrollo psicomotor (a los 9 meses), era adecuado a la edad, según la escala de Sheridan. Este cuadro clínico corresponde a un síndrome de Russel-Silver destacando como aspectos diferenciadores en nuestro paciente la asimetría corporal cruzada y la ausencia de retraso de crecimiento intrauterino (AU)
Subject(s)
Male , Infant , Humans , Syndrome , Craniofacial Abnormalities , Bone and Bones , Abnormalities, Multiple , Fetal Growth RetardationABSTRACT
Posterior choanal atresia is a congenital malformation which can occur isolated or in combination to additional malformations. In CHARGE association the other anomalies are: coloboma, heart disease, retarded development/growth or central nervous system abnormalities, genital hypoplasia or hypogonadism and ear abnormalities or deafness. The authors present three cases of CHARGE association and they also review the clinical findings required for the diagnosis.
Subject(s)
Abnormalities, Multiple , Central Nervous System/abnormalities , Choanal Atresia , Coloboma , Deafness , Female , Genitalia/abnormalities , Growth Disorders , Heart Diseases/congenital , Humans , Infant, Newborn , Intellectual Disability , MaleABSTRACT
Two different forms of dyssegmental dysplasia, mild and severe, can be distinguished on clinical, radiographic and chondro-osseous morphologic grounds. The milder Rolland-Desbuquois type is frequently characterised by survival beyond the newborn period. The lethal Silverman-Handmaker type has distinctive and more severe findings. In this paper, a rare case of the Rolland-Desbuquois type is presented. The case is unusual because although it was the milder form, the child died on the 10th day of life.
