[Neonatal withdrawal syndrome in twins born to a mother on methadone substitution]. / Syndrome de sevrage néo-natal chez des jumeaux d'une mère sous traitement de substitution par méthadone.

We report the cases of two female twins whose mother was taking methadone substitution therapy. These cases demonstrate the unpredictable nature of the neonatal withdrawal syndrome. One baby developed signs of withdrawal late 10 days after birth. She had a less severe syndrome than her twin sister who was hypotrophic and developed signs on day 1 which persisted for 6 weeks.