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Gene-marked autologous hematopoietic stem cell transplantation of autoimmune disease.
Burt, R K; Brenner, M; Burns, W; Courier, E; Firestein, G; Hahn, B; Heslop, H; Link, C; McFarland, H; Roland, M; Territo, M; Tsokos, G; Traynor, A.
J Clin Immunol ; 20(1): 1-9, 2000 Jan.
Article in English | MEDLINE | ID: mdl-10798601

ABSTRACT

In phase I (safety) trials, we have demonstrated the feasibility of autologous hematopoietic stem cell transplantation (HSCT) for patients with autoimmune diseases. Although this review comments on results of our phase I trials, the focus is on phase II (efficacy) trials using gene-marked autologous stem cells.


Subject(s)
Autoimmune Diseases/therapy , Hematopoietic Stem Cell Transplantation , Clinical Trials, Phase I as Topic , Clinical Trials, Phase II as Topic , Genetic Vectors , Hematopoietic Stem Cells/physiology , Humans , Transplantation, Autologous
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