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1.
J Obstet Gynaecol ; 32(2): 166-72, 2012 Feb.
Article in English | MEDLINE | ID: mdl-22296430

ABSTRACT

A contraceptive method that suits an individual's needs may be more consistently used leading to greater user satisfaction. We therefore wanted to investigate whether a woman's current contraceptive choice corresponded with qualities identified by women as important. An anonymous survey was completed by women in their reproductive years, living in the North East of England, before seeing a healthcare professional. A total of 177 English-speaking women, who were sexually active and of reproductive age, completed questionnaires giving a response rate of 54%. A correlation was found between the current contraceptive used and the previously stated qualities felt to be important when choosing a method (p = 0.034, χ(2)-test). Similarly, a relationship was found between the current contraceptive method and reasons stated against choosing a contraceptive (p = 0.002, χ(2)-test). Overall, British women are generally satisfied with their chosen contraceptive method.


Subject(s)
Consumer Behavior , Contraception , Adolescent , Adult , Choice Behavior , England , Female , Humans , Middle Aged , Surveys and Questionnaires , Young Adult
2.
Diabet Med ; 24(7): 778-83, 2007 Jul.
Article in English | MEDLINE | ID: mdl-17535290

ABSTRACT

AIM: To determine potential for amelioration of recurrent severe hypoglycaemia without worsening in overall control in individuals with long-standing Type 1 diabetes (T1DM). METHODS: Twenty-one people with T1DM characterized by altered hypoglycaemia awareness and debilitating severe hypoglycaemia were randomized in a pilot 24-week prospective study to optimized analogue therapy (ANALOGUE; lispro/glargine); continuous subcutaneous insulin infusion therapy (CSII; lispro); or re-education with relaxation of blood glucose targets on existing conventional insulin regimen (EDUCATION). Glycaemic profiles and duration of biochemical hypoglycaemia were measured by continuous subcutaneous glucose monitoring and self-monitored blood glucose. RESULTS: Further severe hypoglycaemia was prevented in five participants (71%) in each group (P = 0.06). Incidence of severe hypoglycaemia was: 0.6 (ANALOGUE), 0.9 (CSII), and 3.7 (EDUCATION) episodes per patient year. Restoration of hypoglycaemia awareness was confirmed by validated questionnaire in three (43%) ANALOGUE, four (57%) CSII and five (71%) EDUCATION patients. Glycated haemoglobin (HbA1c) was significantly improved in the ANALOGUE group between weeks 0 and 24 (8.6 +/- 1.1 vs. 7.6 +/- 0.8%; P = 0.04 for change). Non-significant improvement was seen in the CSII group (8.5 +/- 1.9 vs. 7.4 +/- 1.0%; P = 0.06). No change in HbA1c was seen in the EDUCATION group (8.5 +/- 1.1 vs. 8.3 +/- 1.0%; P = 0.54). There were no episodes of diabetic ketoacidosis or any other adverse events in any group. CONCLUSIONS: In this pilot randomized trial comparing optimized ANALOGUE, CSII or EDUCATION alone in unselected individuals with recurrent severe hypoglycaemia, we show potential for restoring hypoglycaemia awareness and preventing further severe hypoglycaemia with concomitant improvement in glycaemic control in ANALOGUE and CSII groups.


Subject(s)
Diabetes Mellitus, Type 1/complications , Hypoglycemia/prevention & control , Hypoglycemic Agents/therapeutic use , Insulin/analogs & derivatives , Adult , Blood Glucose/metabolism , Blood Glucose Self-Monitoring/methods , Diabetes Mellitus, Type 1/prevention & control , Female , Humans , Hypoglycemia/blood , Hypoglycemic Agents/blood , Insulin/therapeutic use , Insulin Glargine , Insulin Infusion Systems , Insulin Lispro , Insulin, Long-Acting , Male , Patient Education as Topic/methods , Pilot Projects , Prospective Studies , Secondary Prevention
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