ABSTRACT
Pseudo-signet ring parietal cell vacuolation has been described as a mimic of invasive signet ring cell carcinoma. Moreover, signet ring cell carcinoma has been described in a fundic gland polyp. This case demonstrates parietal cell vacuolation in a fundic gland polyp in a patient on a long-term proton pump inhibitor.
Subject(s)
Carcinoma, Signet Ring Cell/diagnosis , Gastric Fundus/pathology , Polyps/diagnosis , Stomach Neoplasms/diagnosis , Aged , Biopsy , Diagnosis, Differential , Gastric Fundus/diagnostic imaging , Gastric Fundus/drug effects , Gastritis/drug therapy , Gastroscopy , Humans , Male , Polyps/chemically induced , Proton Pump Inhibitors/adverse effects , Stomach Neoplasms/chemically inducedABSTRACT
Breast carcinoma in males is rare although a 4-fold increased incidence is reported in HIV-infected men. Herein we report a case of invasive breast carcinoma in a HIV-positive man on antiretroviral therapy. The carcinoma was associated with features of florid gynecomastia, atypical ductal hyperplasia, ductal carcinoma in situ, and columnar cell change. This combination of morphological changes has not previously been reported in the context of male breast carcinoma and their etiopathological associations are discussed.
Subject(s)
Breast Neoplasms, Male/pathology , Carcinoma, Intraductal, Noninfiltrating/pathology , Gynecomastia/etiology , HIV Infections , Adult , Antiretroviral Therapy, Highly Active , Breast Neoplasms, Male/complications , Carcinoma, Intraductal, Noninfiltrating/complications , Humans , MaleABSTRACT
Xanthomas are common in cutaneous sites but may also be seen in unusual locations. In view of the paucity of reported cases, the occurrence of such lesions within the breast stroma would appear to be either unusual, underreported, or ignored. Indeed, most reports of the few breast xanthomas and of the even fewer xanthomatous fibroadenomas reported have appeared in the older literature. Herein, a case of fibroadenoma with multiple foci of xanthoma is reported, the literature is briefly reviewed, and the apparent difference between the previous cases and the current case is highlighted.
Subject(s)
Breast Neoplasms/pathology , Fibroadenoma/pathology , Breast Neoplasms/diagnosis , Female , Fibroadenoma/diagnosis , Humans , Middle Aged , Xanthomatosis/pathologySubject(s)
Famous Persons , Music , Pathology, Surgical , Breast Diseases/pathology , Colonic Neoplasms/pathology , Female , HumansABSTRACT
Membranous fat necrosis is an unusual type of fat necrosis occurring in the breast and normally involves the parenchyma. This report describes an apparently unique intraductal focus in a fibroadenoma following prior needling. Displacement of fatty tissue in the form of membranous fat necrosis within ducts could be added to the list of histological features following core biopsy.
Subject(s)
Breast Neoplasms/pathology , Fat Necrosis/pathology , Fibroadenoma/pathology , Female , Humans , Middle AgedSubject(s)
Drama , Hemangioma/pathology , Literature, Medieval , Skin Neoplasms/pathology , Humans , Pathology, SurgicalABSTRACT
Melanosis coli is a well-known occurrence in colonic biopsies. The condition is, however, reportedly absent in both neoplastic and hyperplastic colonic polyps. Herein, we describe its occurrence in 10 hyperplastic colonic polyps, some of which showed melanosis in adjacent biopsied mucosa, and 2 colonic adenomata.
Subject(s)
Adenoma/epidemiology , Colonic Neoplasms/epidemiology , Colonic Polyps/epidemiology , Melanosis/epidemiology , Adenoma/pathology , Aged , Aged, 80 and over , Biopsy , Colon/pathology , Colonic Neoplasms/pathology , Colonic Polyps/pathology , Comorbidity , Female , Humans , Hyperplasia/epidemiology , Hyperplasia/pathology , Male , Melanosis/pathology , Middle Aged , PrevalenceABSTRACT
Pseudomembranes in colonic biopsies are normally associated with antibiotic related pseudomembranous colitis. Although pseudomembranes have rarely been reported in other conditions, their presence in rectal prolapse has not been previously reported.
