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1.
J Public Health (Oxf) ; 46(2): e240-e247, 2024 May 29.
Article in English | MEDLINE | ID: mdl-38389318

ABSTRACT

BACKGROUND: Policymaking regarding physical activity (PA) and diet plays an important role in childhood health promotion. This study provides a detailed examination of Scottish government and policy for child and adolescent PA and diet and discusses strengths and areas for improvement. METHODS: Scottish policy documents (n = 18 [PA]; n = 10 [diet])-published in 2011-20-were reviewed for grading using an adapted version of the Health-Enhancing Physical Activity Policy Audit Tool Version 2. RESULTS: There is clear evidence of leadership and commitment to improving PA and diet and tackling obesity in children and adolescents. The allocation of funds and resources for policy implementation has increased substantially over the past decade. Progress through early key stages of public policymaking-policy agenda and formation-has improved. However, there is limited information on later key stages, including policy monitoring and evaluation. CONCLUSIONS: Childhood PA and diet are a clear priority in Scotland, and PA and diet policies clearly support the desire to achieve other goals, including reducing inequalities and increasing active travel in Scotland. Nonetheless, future policies should be further strengthened through clear(er) plans of implementation, and monitoring and evaluation to support their societal impact.


Subject(s)
Diet , Exercise , Health Policy , Health Promotion , Humans , Scotland , Child , Adolescent , Health Promotion/methods , Pediatric Obesity/prevention & control , Policy Making , Nutrition Policy
2.
J Exerc Sci Fit ; 20(4): 317-322, 2022 Oct.
Article in English | MEDLINE | ID: mdl-36033941

ABSTRACT

Background: The 2021 Active Healthy Kids Scotland Report Card aimed to identify secular trends and socio-economic inequalities, and to assess the physical activity and health of children and youth prior to COVID-19. Methods: An expert panel searched for data published in 2018-2020. Grades were assigned to nationally representative data using the Active Healthy Kids Global Alliance methodology. Results: The expert panel, following national consultation, awarded the following grades: Community/Environment B-, Organized Sport and Physical Activity B-, Government/Policy C-/C+, Active Transportation C-, Family/Peers D-, Recreational Screen Time F. Five indicators were graded inconclusive (INC): Overall Physical Activity; Active Play; Physical Fitness; Diet; Obesity. Grades have remained stable or declined, and surveillance has reduced, increasing the number of INC grades. There were marked socio-economic inequalities for eight indicators (Recreational Screen Time; Overall Physical Activity; Organized Sport & Physical Activity; Active Transportation; Diet; Obesity; Family/Peers; Community/Environment). Conclusions: Despite a decade of favorable policy, physical activity and health of children and youth has not improved, and marked socio-economic inequalities continue to persist in Scotland. There is a clear need for greater monitoring of physical activity and health, and improved policy implementation and evaluation, particularly as many indicators and related inequalities may have worsened following the COVID-19 pandemic.

3.
Front Nutr ; 9: 851826, 2022.
Article in English | MEDLINE | ID: mdl-35571908

ABSTRACT

Introduction: Food systems are challenged to provide healthy, sustainable and affordable foods. From a consumer perspective, identifying healthy, sustainable and affordable choices based on individual food products rather than diets could promote better shopping choices. Objective: To identify foods and drinks with the highest nutritional quality and lowest greenhouse gas emissions (GHGE) and price. We also assessed how a combination of these indicators (e.g., nutritional quality, GHGE and price) for food categories aligned with current United Kingdom dietary recommendations. Materials and Methods: We performed a secondary analysis of the National Diet and Nutrition Survey (NDNS) nutrient databank year 11 (2018/2019). Spearman correlation coefficients were used to assess the strength of relationships between nutritional quality, environmental impact and/or prices per 100 kcal. In addition, we developed an optimized nutritional quality, GHGE and price score for each food or drink item based on the overall medians for each of these indicators. Results: Median nutritional value was highest for fruit and vegetables, whilst median GHGE and price was lower for starchy carbohydrates, fats and items of which consumption should be limited. The relative proportions of foods considered the most nutritious and with a low GHGE and price in each of the food categories, on a per 100 kcal basis, were comparable to the proportions in the Eatwell Guide, except for the proportion of fruits and vegetables being smaller and the proportion of potatoes, bread, rice, pasta, and other starchy carbohydrates being larger in our analysis. Conclusion: Public health efforts should consider the impact of dietary choices not only in terms of nutritional quality but also in terms of environmental and economic impact. Our food-based analysis shows a large variation in nutritional quality, GHGE and price within and across food categories, which provides consumers with opportunities for "food swaps" that are more nutritious and have lower GHGE and price.

4.
Article in English | MEDLINE | ID: mdl-35328877

ABSTRACT

Food-based analyses of the healthiness, environmental sustainability and affordability of processed and ultra-processed foods are lacking. This paper aimed to determine how ultra-processed and processed foods compare to fresh and minimally processed foods in relation to nutritional quality, greenhouse gas emissions and cost on the food and food group level. Data from the National Diet and Nutrition Survey nutrient databank year 11 (2018/2019) were used for this analysis. Median and bootstrapped medians of nutritional quality (NRF8.3 index), greenhouse gas emissions (gCO2-equivalents) and cost (in GBP) were compared across processing categories. An optimal score based on the medians was created to identify the most nutritional, sustainable, and affordable options across processing categories. On a per 100 kcal basis, ultra-processed and processed foods had a lower nutritional quality, lower greenhouse gas emissions, and were cheaper than minimally processed foods, regardless of their total fat, salt and/or sugar content. The most nutritious, environmentally friendly, and affordable foods were generally lower in total fat, salt, and sugar, irrespective of processing level. The high variability in greenhouse gas emissions and cost across food groups and processing levels offer opportunities for food swaps representing the healthiest, greenest, and most affordable options.


Subject(s)
Energy Intake , Greenhouse Gases , Carbohydrates , Diet , Environment , Fast Foods , Food Handling , Nutritive Value , Sugars , United Kingdom
5.
Article in English | MEDLINE | ID: mdl-30805199

ABSTRACT

BACKGROUND: Being overweight or obese following breast cancer diagnosis can increase cancer recurrence and mortality, so effective interventions for weight loss in this group could enhance survival. A pilot randomised controlled trial was conducted to assess whether a weight loss programme comprising generic Weight Watchers® referral offered to women treated for breast cancer with or without additional breast cancer-tailored dietetic support is feasible and shows promise for improving weight and quality of life (QoL). METHODS: Participants were randomly allocated to 3 groups: Weight Watchers® referral (for 12 sessions of meetings and digital tools) plus 5 breast cancer-tailored dietitian-led group support sessions (WW Plus: n = 14), Weight Watchers® referral only (WW: n = 16) or control (Weight Watchers® referral after 3 months, n = 15). Feasibility was assessed based on retention rate, recruitment and randomisation process, meeting attendance, suitability of the setting and outcome measurement tools, unintended consequences, cost and observations of the dietetic sessions. Outcomes were measured at 0, 3 ('trial exit') and 12 months post intervention. RESULTS: The response rate to the invitation was 43% (140/327) of whom 58 were eligible and 45 (median age 61.0 years; body mass index 30.2 kg/m2) were randomised. Data from 38 (84%) and 30 (67%) participants were available at trial exit and 12 months respectively. Feasibility issues included slow recruitment process, lack of blinding throughout, weighing scales not measuring > 150 kg, lack of clear instructions for completing QoL questionnaire and workload and time pressures in delivering dietetic sessions. Participants had good attendance rate at group meetings and no serious unintended consequences were reported. WW Plus was most expensive to run. Mean (95% CI) weight change at trial exit was - 3.67 kg (- 5.67, - 2.07) in WW Plus, - 6.03 kg (- 7.61, - 4.44) in WW group and + 0.19 kg (- 1.45, + 1.83) in control group. About 40% of the WW Plus, 64% of the WW group and 56% of the control group lost ≥ 5% of their baseline weight by 12 months. All groups showed promise for improving QoL at trial exit but only the WW group maintained significant improvements from baseline at 12 months. CONCLUSIONS: The trial procedures were feasible, with some modifications. This pilot trial indicates the benefits of providing free WW vouchers for weight loss maintenance and improving QoL but provided no evidence that including additional dietetic support would add any extra value. Further research with WW with long-term follow-up should be undertaken to assess weight loss sustainability and benefit on health outcomes in this patient group. TRIAL REGISTRATION: ISRCTN-29623418.

6.
Nutr Diet ; 76(5): 521-531, 2019 11.
Article in English | MEDLINE | ID: mdl-29943443

ABSTRACT

AIM: To determine whether a food frequency questionnaire (FFQ) and a short dietary assessment tool can be used to accurately estimate the Eatwell Guide proportions (a plate-based food model) of diets of adults living in Scotland. METHODS: The cross-sectional study was conducted as a follow up of the 2010 Scottish Health Survey (participants aged 18-65 years old). Proportions of the Eatwell Guide food groups (starchy carbohydrates, fruits and vegetables (F&V), dairy and alternatives, protein foods and oils and spreads) were calculated from the Scottish Health Survey Eating Habits Module (SHeS EHM), Scottish Collaborative Group FFQ (SCG FFQ) and a seven-day estimated food diary (reference method), and compared using the Aitchison method and Wilcoxon Signed-Rank Test. Bland-Altman analyses assessed mean difference and 95% limits of agreement between the methods for each food group. RESULTS: Ninety-six adults were included (mean (SD) age = 51.4 (11.1) years; body mass index = 27.1 (4.9) kg/m2 ; 58% female). The SCG FFQ scored a lower median Aitchison distance (1.47) than the SHeS EHM (1.99) (P < 0.001), showing greater agreement with the reference method (P < 0.001). Bland-Altman plots also showed better agreement for the SCG FFQ than the SHeS EHM. Poorest agreement was for starchy carbohydrates (both methods), protein foods (SHeS EHM) and dairy (SCG FFQ). CONCLUSIONS: The SCG FFQ could be used to estimate Eatwell Guide proportions and monitor compliance to the Eatwell Guide recommendations and could be improved with small changes. The SHeS EHM is less suitable, but additional questions on dairy foods, and oils and spreads would improve its ability to estimate the Eatwell Guide proportions.


Subject(s)
Diet Records , Energy Intake , Nutrition Assessment , Adolescent , Adult , Aged , Female , Humans , Male , Middle Aged , Reproducibility of Results , Scotland , Surveys and Questionnaires , Young Adult
7.
Appetite ; 117: 224-233, 2017 10 01.
Article in English | MEDLINE | ID: mdl-28536058

ABSTRACT

Seafood is recommended as part of a healthy, balanced introductory diet however, consumption rates are low in young children. Research has previously investigated the influences to seafood consumption in consumers and non-consumers however the importance of these factors in mothers' decisions on whether to provide seafood for their child during the early years is unknown. This study aimed to measure the importance of factors that influence mothers' decisions on providing seafood for their child during infant and young child feeding (six months to four years). A mixed method Q methodology and cognitive interview approach was used with 32 mothers in Scotland. Despite a large consensus of opinion between mothers (n = 20) on the importance of factors on their decision-making, two viewpoints emerged highlighting an importance placed on food attributes and the infant, and convenience and family-centred. This study is the first to quantify the influences on the decision to provide seafood during early years' feeding and could be used to inform and tailor seafood-based dietary promotions and interventions for parents.


Subject(s)
Child Nutritional Physiological Phenomena , Diet, Healthy , Feeding Methods , Infant Nutritional Physiological Phenomena , Maternal Behavior , Models, Psychological , Seafood , Adult , Child Nutritional Physiological Phenomena/ethnology , Child, Preschool , Consumer Behavior , Cooking , Decision Making , Diet, Healthy/ethnology , Diet, Healthy/psychology , Family Characteristics/ethnology , Feeding Methods/psychology , Female , Food Preferences/ethnology , Food Preferences/psychology , Humans , Infant , Infant Food/adverse effects , Infant Nutritional Physiological Phenomena/ethnology , Male , Maternal Behavior/ethnology , Patient Compliance/ethnology , Scotland , Seafood/adverse effects , Time Factors
8.
Neurology ; 88(5): 449-455, 2017 01 31.
Article in English | MEDLINE | ID: mdl-28053008

ABSTRACT

OBJECTIVE: To assess the association between Mediterranean-type diet (MeDi) and change in brain MRI volumetric measures and mean cortical thickness across a 3-year period in older age (73-76 years). METHODS: We focused on 2 longitudinal brain volumes (total and gray matter; n = 401 and 398, respectively) plus a longitudinal measurement of cortical thickness (n = 323), for which the previous cross-sectional evidence of an association with the MeDi was strongest. Adherence to the MeDi was calculated from data gathered from a food frequency questionnaire at age 70, 3 years prior to the baseline imaging data collection. RESULTS: In regression models adjusting for relevant demographic and physical health indicators, we found that lower adherence to the MeDi was associated with greater 3-year reduction in total brain volume (explaining 0.5% of variance, p < 0.05). This effect was half the size of the largest covariate effect (i.e., age). Cross-sectional associations between MeDi and baseline MRI measures in 562 participants were not significant. Targeted analyses of meat and fish consumption did not replicate previous associations with total brain volume or total gray matter volume. CONCLUSIONS: Lower adherence to the MeDi in an older Scottish cohort is predictive of total brain atrophy over a 3-year interval. Fish and meat consumption does not drive this change, suggesting that other components of the MeDi or, possibly, all of its components in combination are responsible for the association.


Subject(s)
Aging/pathology , Brain/diagnostic imaging , Diet, Mediterranean , Aged , Cross-Sectional Studies , Female , Gray Matter/diagnostic imaging , Humans , Longitudinal Studies , Magnetic Resonance Imaging , Male , Organ Size , Prospective Studies , Regression Analysis , Scotland , Sex Characteristics , Surveys and Questionnaires
9.
Appetite ; 108: 277-287, 2017 01 01.
Article in English | MEDLINE | ID: mdl-27737771

ABSTRACT

The first year of a child's life is a key period of transition from an exclusive milk diet to solid foods to meet growing nutritional demands. An increased requirement for nutrients includes the introduction of protein-rich solid foods, such as seafood, which additionally provides valuable omega-3 fatty acids. However, consumption of seafood is low in the British child population. The aim of this study was to identify maternal perceptions of the factors that can influence the decision on whether to provide seafood during early years' feeding using a multi-method qualitative study design. A total of 26 discussions posted by mothers on parenting websites; Mumknowsbest, Mumsnet and Netmums, accessed July 2013, together with discussions from six focus groups (February-July 2014) in the North East of Scotland were included for thematic qualitative analysis. Discussions on the inclusion of seafood during the early years were centred across four interrelating themes; - food-related attributes, mother-centred aspects, family-centred aspects, and external information sources. Concerns regarding safety and mothers' limited knowledge and skills on seafood were apparent from discussions; however, the practicalities of providing a cost effective family meal were also issues raised by mothers. An understanding of the numerous and sometimes contradictory influences on mothers' decisions to include seafood during early years' period could be used to develop strategies to help increase regular seafood consumption. In particular, ensuring formal information and guidance clearly addresses the safety concerns of mothers and the development of practical education schemes to encourage and teach cooking skills should be considered.


Subject(s)
Child Development , Child Nutritional Physiological Phenomena , Diet, Healthy , Feeding Behavior , Maternal Behavior , Patient Compliance , Seafood , Child, Preschool , Cooking/economics , Diet, Healthy/economics , Family , Female , Fisheries/economics , Focus Groups , Food Contamination , Health Knowledge, Attitudes, Practice , Humans , Infant , Internet , Male , Qualitative Research , Scotland , Seafood/adverse effects , Seafood/economics , Social Networking
10.
Community Pract ; 89(4): 36-41, 2016 Apr.
Article in English | MEDLINE | ID: mdl-27183751

ABSTRACT

There is no evidence available indicating whether popular infant and young child feeding (IYCF) cookbooks provide nutritious options for home-cooking, what the most common food types are within the recipes, and what accompanying dietary advice is provided to parents. This study surveyed available IYCF cookbooks from local libraries and Amazon UK's top 20 bestsellers (May to July 2013 to examine the prevalence and nutritional content of cookbook recipes comparing these to recommendations whilst investigating the messages portrayed towards parents on giving different foods to their child during IYCF. Vegetable-based recipes (median=29) predominated main-meal options while a proportional number of red meat, poultry and seafood-based recipes were included providing parents with options of protein-rich recipes for their young child. These home-cooked recipes adequately met or exceeded age-specific dietary recommendations. Mixed messages were apparent on the inclusion of foods during IYCF within and across these cookbooks, in particular for seafood, highlighting a lack of consistent advice portrayed to parents during the early years. Community-based health professionals should advise parents of the inconsistent and incorrect messages on food inclusion portrayed in some IYCF cookbooks and guide them towards formal recommendations.


Subject(s)
Cookbooks as Topic , Cooking , Infant Food , Humans , Infant , Meat , Nutritive Value , Vegetables
11.
Matern Child Nutr ; 12(4): 860-8, 2016 10.
Article in English | MEDLINE | ID: mdl-25895052

ABSTRACT

Seafood consumption is recommended as part of a healthy, balanced diet. Under-exposure to seafood during early years feeding, when taste and food acceptance is developed, may impact on the future development of a varied diet. This study aimed to investigate the availability and nutritional content of seafood in commercial infant meals compared to the other food types. A survey was conducted of all commercial infant main meal products available for purchase in supermarkets, high street retailers and online stores within the United Kingdom. The primary food type (seafood, poultry, meat and vegetables) within each product, nutritional composition per 100 g, and ingredient contribution were assessed. Of the original 341 main meal products seafood (n = 13; 3.8%) was underrepresented compared to poultry (103; 30.2%), meat (121; 35.5%) and vegetables (104; 30.5%). The number of the seafood meals increased three years later (n = 20; 6.3%) vegetable meals remained the largest contributor to the market (115; 36.4%) with meat (99; 31.3%) and poultry (82; 26.0%) both contributing slightly less than previously. Seafood-based meals provided significantly higher energy (83.0 kcal), protein (4.6 g), and total fat (3.2 g) than vegetable (68 kcal, 2.7 g, 1.9 g), meat (66 kcal, 3.0 g, 2.1 g) and poultry-based meals (66 kcal, 3.0 g, 2.1 g) and higher saturated fat (1.3 g) than poultry (0.4 g) and vegetable-based (0.6 g) meals (all per 100 g) which may be attributed to additional dairy ingredients. Parents who predominantly use commercial products to wean their infant may face challenges in sourcing a range of seafood products to enable the introduction of this food into the diet of their infant.


Subject(s)
Diet , Infant Food , Seafood , Weaning , Animals , Dietary Carbohydrates/administration & dosage , Dietary Fats/administration & dosage , Dietary Fiber/administration & dosage , Dietary Proteins/administration & dosage , Humans , Infant , Nutritive Value , Poultry , Red Meat , United Kingdom , Vegetables
12.
Int J Behav Nutr Phys Act ; 12: 98, 2015 Aug 04.
Article in English | MEDLINE | ID: mdl-26238695

ABSTRACT

BACKGROUND: Food and drink purchasing habits of pupils out of school at lunchtime may be contributing to poor dietary intakes and overweight and obesity. The aim of this study was to identify the places from which purchases were made, types of food and drinks purchased and, the reasons for purchasing food or drinks out of school. METHODS: A survey of the food and drinks purchasing habits of secondary school pupils (11-16 yrs) out of school at lunchtime was conducted in Scotland in 2010. A face-to-face interview and a self-completion questionnaire was designed to identify the food outlets used at lunchtime, types of food and drinks purchased and pupils' reasons for purchasing food or drinks out of school. Height and weight were measured and BMI centiles used to classify pupils as normal weight, overweight or obese. Results were compared by age group, sex, BMI group and level of socio-economic deprivation. RESULTS: Of the 612 pupils who completed the survey, 97 % reported having access to places selling food or drinks out of school at lunchtime, and of these 63 % made purchases. A higher proportion of pupils from more deprived areas reported purchasing food or drinks out of school, but the proportion making purchases did not differ significantly by sex or BMI group. Supermarkets were the outlets from which pupils reported most often making purchases, with fewer purchasing food or drinks from fast food takeaways, and this did not differ significantly by socio-economic deprivation. Reasons for making purchases included availability of preferred food and drinks, some of which are restricted for sale in schools, and social reasons, such as wanting to be with friends. Sandwiches and non-diet soft drinks were items most commonly purchased, followed by confectionery and diet soft drinks. However, less than 10 % of all the secondary school pupils reported purchasing these foods every day. CONCLUSIONS: Supermarkets, not just fast food outlets, should be considered when developing strategies to improve the dietary habits of pupils at lunchtime. The importance of food preferences and social reasons for purchasing food and drinks need to be acknowledged and integrated in future interventions.


Subject(s)
Commerce , Diet , Fast Foods , Feeding Behavior , Motivation , Schools , Adolescent , Body Weight , Carbonated Beverages , Child , Female , Food Preferences , Food Services , Friends , Humans , Lunch , Male , Obesity , Overweight , Scotland , Surveys and Questionnaires
13.
Eur Respir J ; 45(4): 1027-36, 2015 Apr.
Article in English | MEDLINE | ID: mdl-25359350

ABSTRACT

Are maternal vitamin D and E intakes during pregnancy associated with asthma in 10-year-old children? In a longitudinal study of 1924 children born to women recruited during pregnancy, maternal vitamin D intake during pregnancy was assessed by the Food Frequency Questionnaire (FFQ) and vitamin E by FFQ and plasma α-tocopherol; respiratory questionnaires were completed for the 10-year-old children. Their treatment for asthma was also ascertained using administrative data. Longitudinal analyses included data collected at 1, 2, 5 and 10 years. Symptom data were available for 934 (49%) children and use of asthma medication for 1748 (91%). In the children maternal vitamin D intake during pregnancy was negatively associated with doctor-diagnosed asthma at 10 years of age (OR per intake quintile 0.86, 95% CI 0.74-0.99) and over the first 10 years (hazard ratio 0.90, 95% CI 0.81-1.00). Maternal plasma α-tocopherol at 11 weeks gestation was negatively associated with children receiving asthma treatment (OR per standard deviation increase 0.52, 95% CI 0.31-0.87). Maternal vitamin E intake was negatively associated with doctor-diagnosed asthma (OR 0.89, 95% CI 0.81-0.99) in the first 10 years. Low maternal vitamin D and E intakes during pregnancy are associated with increased risk of children developing asthma in the first 10 years of life. These associations may have significant public health implications.


Subject(s)
Asthma/etiology , Dietary Supplements/adverse effects , Prenatal Exposure Delayed Effects , Vitamin D/adverse effects , Vitamin E/adverse effects , Age Distribution , Asthma/epidemiology , Asthma/physiopathology , Child , Female , Follow-Up Studies , Humans , Incidence , Infant, Newborn , Longitudinal Studies , Pregnancy , Prenatal Care , Risk Assessment , Sex Distribution , Surveys and Questionnaires , Vitamin D/administration & dosage , Vitamin E/administration & dosage
14.
Nutr Cancer ; 67(1): 43-60, 2015.
Article in English | MEDLINE | ID: mdl-25425328

ABSTRACT

Prostate cancer prognosis may therefore be improved by maintaining healthy weight through diet and physical activity. This systematic review looked at the effect of diet and exercise interventions on body weight among men treated for prostate cancer. MEDLINE, EMBASE, CINAHL, and Cochrane Library databases were searched from the earliest record to August 2013. Randomized controlled trials of diet and exercise interventions in prostate cancer patients that reported body weight or body composition changes were included. A total of 20 trials were included in the review. Because of the heterogeneity of intervention components, a narrative review was conducted. Interventions were categorized as diet (n = 6), exercise (n = 8), or a combination of both diet and exercise (n = 6). The sample size ranged from 8 to 155 and the duration from 3 wk to 4 yr. Four diet interventions and 1 combined diet and exercise intervention achieved significant weight loss with mean values ranging from 0.8 kg to 6.1 kg (median 4.5 kg). Exercise alone did not lead to weight loss, though most of these trials aimed to increase fitness and quality of life rather than decrease body weight. Diet intervention, alone or in combination with exercise, can lead to weight loss in men treated for prostate cancer.


Subject(s)
Diet, Reducing , Evidence-Based Medicine , Exercise , Obesity/therapy , Prostatic Neoplasms/complications , Aged , Combined Modality Therapy , Humans , Male , Middle Aged , Obesity/diet therapy , Physical Fitness , Prognosis , Prostatic Neoplasms/diagnosis , Prostatic Neoplasms/therapy , Quality of Life , Randomized Controlled Trials as Topic , Weight Loss
15.
Br J Nutr ; 112(12): 2018-27, 2014 Dec 28.
Article in English | MEDLINE | ID: mdl-25342229

ABSTRACT

Maternal nutritional status during pregnancy has been reported to be associated with childhood asthma and atopic disease. The Avon Longitudinal Study of Parents and Children has reported associations between reduced umbilical cord Fe status and childhood wheeze and eczema; however, follow-up was short and lung function was not measured. In the present study, the associations between maternal Fe status during pregnancy and childhood outcomes in the first 10 years of life were investigated in a subgroup of 157 mother-child pairs from a birth cohort with complete maternal, fetal ultrasound, blood and child follow-up data. Maternal Fe intake was assessed using FFQ at 32 weeks of gestation and Hb concentrations and serum Fe status (ferritin, soluble transferrin receptor and TfR-F (transferrin receptor:ferritin) index) were measured at 11 weeks of gestation and at delivery. Maternal Fe intake, Hb concentrations and serum Fe status were found to be not associated with fetal or birth measurements. Unit increases in first-trimester maternal serum TfR concentrations (OR 1.44, 95% CI 1.05, 1.99) and TfR-F index (OR 1.42, 95% CI 1.10, 1.82) (i.e. decreasing Fe status) were found to be associated with an increased risk of wheeze, while unit increases in serum ferritin concentrations (i.e., increasing Fe status) were found to be associated with increases in standardised mean peak expiratory flow (PEF) (ß 0.25, 95% CI 0.09, 0.42) and forced expiratory volume in the first second (FEV1) (ß 0.20, 95% CI 0.08, 0.32) up to 10 years of age. Increasing maternal serum TfR-F index at delivery was found to be associated with an increased risk of atopic sensitisation (OR 1.35, 95% CI 1.02, 1.79). The results of the present study suggest that reduced maternal Fe status during pregnancy is adversely associated with childhood wheeze, lung function and atopic sensitisation, justifying further studies on maternal Fe status and childhood asthma and atopic disease.


Subject(s)
Anemia, Iron-Deficiency/complications , Asthma/etiology , Ferritins/blood , Hypersensitivity, Immediate/etiology , Iron/blood , Prenatal Exposure Delayed Effects , Receptors, Transferrin/blood , Adult , Anemia, Iron-Deficiency/blood , Asthma/physiopathology , Child , Child, Preschool , Cohort Studies , Female , Forced Expiratory Volume , Hemoglobins/metabolism , Humans , Infant , Infant, Newborn , Iron/administration & dosage , Iron Deficiencies , Iron, Dietary/administration & dosage , Iron, Dietary/blood , Lung/physiopathology , Male , Nutritional Status , Odds Ratio , Peak Expiratory Flow Rate , Pregnancy , Pregnancy Complications/blood , Pregnancy Trimester, First , Respiratory Sounds/etiology , Respiratory Sounds/physiopathology , Surveys and Questionnaires
16.
PLoS One ; 9(3): e91690, 2014.
Article in English | MEDLINE | ID: mdl-24626473

ABSTRACT

Previous functional gene group analyses implicated common single nucleotide polymorphisms (SNPs) in heterotrimeric G protein coding genes as being associated with differences in human intelligence. Here, we sought to replicate this finding using five independent cohorts of older adults including current IQ and childhood IQ, and using both gene- and SNP-based analytic strategies. No significant associations were found between variation in heterotrimeric G protein genes and intelligence in any cohort at either of the two time points. These results indicate that, whereas G protein systems are important in cognition, common genetic variation in these genes is unlikely to be a substantial influence on human intelligence differences.


Subject(s)
Cognition , Genetic Association Studies , Heterotrimeric GTP-Binding Proteins/genetics , Intelligence/genetics , Aged , Aged, 80 and over , Female , Humans , Intelligence Tests , Male , Middle Aged , Polymorphism, Single Nucleotide
17.
J Allergy Clin Immunol ; 133(5): 1317-29, 2014 May.
Article in English | MEDLINE | ID: mdl-24529685

ABSTRACT

BACKGROUND: Preterm birth, low birth weight, and infant catch-up growth seem associated with an increased risk of respiratory diseases in later life, but individual studies showed conflicting results. OBJECTIVES: We performed an individual participant data meta-analysis for 147,252 children of 31 birth cohort studies to determine the associations of birth and infant growth characteristics with the risks of preschool wheezing (1-4 years) and school-age asthma (5-10 years). METHODS: First, we performed an adjusted 1-stage random-effect meta-analysis to assess the combined associations of gestational age, birth weight, and infant weight gain with childhood asthma. Second, we performed an adjusted 2-stage random-effect meta-analysis to assess the associations of preterm birth (gestational age <37 weeks) and low birth weight (<2500 g) with childhood asthma outcomes. RESULTS: Younger gestational age at birth and higher infant weight gain were independently associated with higher risks of preschool wheezing and school-age asthma (P < .05). The inverse associations of birth weight with childhood asthma were explained by gestational age at birth. Compared with term-born children with normal infant weight gain, we observed the highest risks of school-age asthma in children born preterm with high infant weight gain (odds ratio [OR], 4.47; 95% CI, 2.58-7.76). Preterm birth was positively associated with an increased risk of preschool wheezing (pooled odds ratio [pOR], 1.34; 95% CI, 1.25-1.43) and school-age asthma (pOR, 1.40; 95% CI, 1.18-1.67) independent of birth weight. Weaker effect estimates were observed for the associations of low birth weight adjusted for gestational age at birth with preschool wheezing (pOR, 1.10; 95% CI, 1.00-1.21) and school-age asthma (pOR, 1.13; 95% CI, 1.01-1.27). CONCLUSION: Younger gestational age at birth and higher infant weight gain were associated with childhood asthma outcomes. The associations of lower birth weight with childhood asthma were largely explained by gestational age at birth.


Subject(s)
Asthma , Birth Weight , Gestational Age , Premature Birth , Weight Gain , Asthma/epidemiology , Asthma/pathology , Asthma/physiopathology , Europe/epidemiology , Female , Humans , Infant , Infant, Newborn , Male , Premature Birth/epidemiology , Premature Birth/pathology , Premature Birth/physiopathology , Risk Factors
18.
BMC Pregnancy Childbirth ; 13: 114, 2013 May 16.
Article in English | MEDLINE | ID: mdl-23679158

ABSTRACT

BACKGROUND: Exclusive breastfeeding until six months followed by the introduction of solids and continued breastfeeding is recommended by the World Health Organisation. The dominant approach to achieving this has been to educate and support women to start and continue breastfeeding rather than understanding behaviour change processes from a broader perspective. METHOD: Serial qualitative interviews examined the influences of significant others on women's feeding behaviour. Thirty-six women and 37 nominated significant others participated in 220 interviews, conducted approximately four weekly from late pregnancy to six months after birth. Responses to summative structured questions at the end of each interview asking about significant influences on feeding decisions were compared and contrasted with formative semi-structured data within and between cases. Analysis focused on pivotal points where behaviour changed from exclusive breastfeeding to introducing formula, stopping breastfeeding or introducing solids. This enabled us to identify processes that decelerate or accelerate behaviour change and understand resolution processes afterwards. RESULTS: The dominant goal motivating behaviour change was family wellbeing, rather than exclusive breastfeeding. Rather than one type of significant other emerging as the key influence, there was a complex interplay between the self-baby dyad, significant others, situations and personal or vicarious feeding history. Following behaviour change women turned to those most likely to confirm or resolve their decisions and maintain their confidence as mothers. CONCLUSIONS: Applying ecological models of behaviour would enable health service organisation, practice, policy and research to focus on enhancing family efficacy and wellbeing, improving family-centred communication and increasing opportunities for health professionals to be a constructive influence around pivotal points when feeding behaviour changes. A paradigm shift is recommended away from the dominant approach of support and education of individual women towards a more holistic, family-centred narrative approach, whilst acknowledging that breastfeeding is a practical skill that women and babies have to learn.


Subject(s)
Breast Feeding/psychology , Decision Making , Maternal Behavior/psychology , Mother-Child Relations , Adult , Female , Food , Friends/psychology , Humans , Interviews as Topic , Motivation , Qualitative Research , Spouses/psychology , Weaning , Young Adult
19.
Arch Dis Child ; 98(4): 269-73, 2013 Apr.
Article in English | MEDLINE | ID: mdl-23413314

ABSTRACT

BACKGROUND: This was a whole-population study of height, weight and obesity prevalence in 5-6-year-old children born between 1970 and 2006 in the Grampian region, north east Scotland. METHODS: Heights and weights collected as part of routine primary school medical entry were obtained from different sources. Obesity was defined as body mass index (BMI)≥98th centile. RESULTS: Anthropometric measurements were made in 194391 children, mean age 5.6 years (SD 0.8). The mean height z scores rose for those born between 1970-2000 respectively and were static thereafter. Obesity prevalence was non-linear over time and initially fell for birth years 1970-1977, rising between 1977 and 1998 before falling for those born between 1998 and 2006. For the whole population, the prevalence of obesity rose from 1.3% for those born in 1976 to 6.9% for those born in 1998 and fell back to 5.7% for children born in 2006. Obesity was initially highest in girls and most affluent communities but became most prevalent among boys and least affluent communities. CONCLUSIONS: The secular increase in height at school entry in children born in 1970 and afterwards was followed by an increase in weight leading to an initial reduction in obesity prevalence. Whole-population obesity prevalence for children born in the 2000s is now falling but prevalence remains considerably higher compared with those born in the 1970s. Obesity prevalence continues to rise among less affluent communities.


Subject(s)
Body Height , Body Mass Index , Body Weight , Obesity/epidemiology , Body Composition , Child , Child, Preschool , Female , Humans , Linear Models , Longitudinal Studies , Male , Prevalence , School Health Services , Scotland/epidemiology , Sex Distribution , Socioeconomic Factors
20.
Health Psychol ; 32(4): 353-60, 2013 Apr.
Article in English | MEDLINE | ID: mdl-21928903

ABSTRACT

OBJECTIVE: Personality traits are related to numerous health outcomes and health-related behaviors. To date, however, little is known about how personality traits are associated with dietary behavior, an important aspect of lifestyle in the current "toxic food environment." The present study investigated the associations of between Five-Factor Model personality traits, dietary patterns, and body mass index (BMI). METHODS: The sample consisted of 1,091 members of Lothian Birth Cohort 1936 tested at age 70 years. Dietary patterns were measured using a detailed and validated food frequency questionnaire (FFQ). Principal components analysis of the FFQ items identified four dietary dimensions, which were named 'Mediterranean style diet,' 'health aware diet,' 'convenience diet,' and 'sweet foods'. Personality traits were measured with NEO Five-Factor Inventory. The effects of childhood intelligence, education, and sex were controlled. RESULTS: Endorsing the Mediterranean style diet dimension was associated with high Openness and Extraversion, and low Neuroticism. High scores on the health aware diet dimension were associated with high Agreeableness and Conscientiousness. Endorsing the convenience diet dimension was associated with low Openness and high Neuroticism. Preference for sweet foods was associated with low Openness. High BMI was associated with high scores on the convenience diet dimension and low Conscientiousness. CONCLUSIONS: Personality traits, especially Openness, are associated with dietary patterns in older age. The pattern of findings may indicate that, in older people, dietary habits may be less related to how controlled they are and more related to their levels of openness and emotional and social adjustment. Policy implications are discussed.


Subject(s)
Body Mass Index , Feeding Behavior/psychology , Personality , Aged , Diet Surveys , Diet, Mediterranean , Extraversion, Psychological , Female , Humans , Male , Models, Psychological , Personality Inventory
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