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Bioorg Med Chem Lett
; 12(4): 697-9, 2002 Feb 25.
Article
in English
| MEDLINE
| ID: mdl-11844704
ABSTRACT
Benzylidene rhodanines are novel inhibitors of UDP N-acetylmuramate/L-alanine ligase. They showed selective whole-cell activity against the Gram-positive MRSA but not against the Gram-negative Escherichia coli. Their cytotoxic effect on mammalian CHO cells was also evaluated.