Open-source lab hardware: A versatile microfluidic control and sensor platform.

Here we describe a completely integrated and customizable microfluidic control and sensing architecture that can be readily implemented for laboratory or portable chemical or biological control and sensing applications. The compact platform enables control of 32 solenoid valves, a multitude of pumps and motors, a thermo-electric controller, a pressure controller, and a high voltage power supply. It also features two temperature probe interfaces, one relative humidity and ambient temperature sensor, two pressure sensors, and interfaces to an electrical conductivity sensor, flow sensor, and a bubble detector. The platform can be controlled via an onboard microcontroller and requires no proprietary software.

Open-source lab hardware: Driver and temperature controller for high compliance voltage, fiber-coupled butterfly lasers.

This article describes the development of a compact, relatively low-cost, high compliance voltage laser driver that can provide the constant optical laser output required for a range of applications. The system contains an integrated, high-precision temperature controller that can be implemented with butterfly-style lasers containing an internal thermoelectric cooler. The laser parameters can be controlled manually or via an onboard microcontroller. Additionally, an adjustable over-current protection circuit safeguards the laser diode from potential damage.

Open-source lab hardware: Low noise adjustable two-stage gain transimpedance amplifier with DC offset for low-light detection.

An open-source, low noise, low cost, and tunable transimpedance amplifier is presented. The compact circuit board requires few parts and costs less than $65 USD. The transimpedance amplifier is intended for low-light detection and operation with commercial photomultiplier tubes (PMTs). It provides a much more cost-effective acquisition tool compared to competitive products on the market. The system can easily be assembled and modified to suit specific current sensing applications. The amplifier features two variable gains and an adjustable DC offset to optimize dynamic range and suppress potential bias in the signal. With a target bandwidth of DC to 2 Hz and fourth-order Sallen-Key cutoff, the design is ideally suited for various applications in the field of analytical chemistry and biology, such as laser-induced fluorescence detection or chemiluminescence measurements.