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J Clin Immunol ; 34(7): 784-7, 2014 Oct.
Article in English | MEDLINE | ID: mdl-25091287

ABSTRACT

Chronic wounds are a rare complication of X-linked agammaglobulinaemia (XLA). Fastidious organisms such as helicobacter bills have been reported in XLA with chronic wounds but sterile chronic wounds also occur. Hyperbaric Oxygen Therapy has been used in chronic wounds but has not previously been reported in primary antibody deficiencies. We present a case of a chronic wound in a patient with XLA refractory to antimicrobial therapy that made a remarkable recovery following Hyperbaric Oxygen Therapy.


Subject(s)
Agammaglobulinemia/therapy , Epithelium/drug effects , Genetic Diseases, X-Linked/therapy , Hyperbaric Oxygenation , Leg Injuries/therapy , Wound Infection/therapy , Adult , Agammaglobulinemia/complications , Agammaglobulinemia/immunology , Anti-Bacterial Agents/administration & dosage , Chronic Disease , Drug Resistance , Epithelium/pathology , Genetic Diseases, X-Linked/complications , Genetic Diseases, X-Linked/immunology , Humans , Infant , Inflammation Mediators/metabolism , Leg Injuries/complications , Leg Injuries/immunology , Recovery of Function , Recurrence , Wound Infection/etiology , Wound Infection/immunology
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