Subject(s)
Antibodies, Monoclonal, Humanized , Asthma , Humans , Antibodies, Monoclonal, Humanized/adverse effects , Antibodies, Monoclonal, Humanized/therapeutic use , Asthma/drug therapy , Asthma/chemically induced , Female , Male , Middle Aged , Adult , Rhinitis/chemically induced , Rhinitis/drug therapy , Severity of Illness Index , Anti-Asthmatic Agents/adverse effects , Anti-Asthmatic Agents/therapeutic use , AgedABSTRACT
Acinic cell carcinoma (ACC) is a low grade malignant tumor of the salivary glands. Primary ACC affects most frequently the parotid gland and can rarely arise in the minor salivary glands of the oral cavity, pharynx and larynx. It is extremely rare in the nasal cavity; to our knowledge only 18 cases of primary ACC of the nasal cavity are reported in the English-written literature. Herein we report a case of acinic cell carcinoma of the nasal cavity, describe the clinical, radiological and microscopic features of this uncommon presentation and finally provide a discussion in the light of relevant literature.
Subject(s)
Carcinoma, Acinar Cell , Nasal Cavity , Nasal Septum , Nose Neoplasms , Salivary Gland Neoplasms , Adult , Biopsy , Carcinoma, Acinar Cell/diagnostic imaging , Carcinoma, Acinar Cell/pathology , Female , Humans , Magnetic Resonance Imaging , Nasal Cavity/diagnostic imaging , Nasal Cavity/pathology , Nasal Septum/diagnostic imaging , Nasal Septum/pathology , Nose Neoplasms/diagnostic imaging , Nose Neoplasms/pathology , Salivary Gland Neoplasms/diagnostic imaging , Salivary Gland Neoplasms/pathologyABSTRACT
Surgeons conventionally use electrocautery dissection and surgical clip appliers to harvest free flaps. The ultrasonic Harmonic Scalpel is a new surgical instrument that provides high-quality dissection and hemostasis and minimizes tissue injury. The aim of this study was to evaluate the effectiveness and advantages of the ultrasonic Harmonic Scalpel compared to conventional surgical instruments in free flap surgery. This prospective study included 20 patients who underwent head and neck reconstructive surgery between March 2009 and May 2010. A forearm free flap was used for reconstruction in 12 patients, and a fibular flap was used in 8 patients. In half of the patients, electrocautery and surgical clips were used for free flap harvesting (the EC group), and in the other half of the patients, ultrasonic dissection was performed using the Harmonic Scalpel (the HS group). The following parameters were significantly lower in the HS group compared to the EC group: the operative time of flap dissection (35% lower in the HS group), blood loss, number of surgical clips and cost of surgical materials. This study demonstrated the effectiveness of the Harmonic Scalpel in forearm and fibular free flap dissections that may be extended to other free flaps.
