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1.
Nanotechnology ; 19(43): 435705, 2008 Oct 29.
Article in English | MEDLINE | ID: mdl-21832709

ABSTRACT

In this investigation, crystalline ruthenium oxide square nanorods have been observed via scanning electron microscopy (SEM) to melt at significantly lower temperatures than the melting temperature of bulk ruthenium oxide (1200 °C) at a measured substrate temperature of only 180 °C. The heating and subsequent melting of these nanorods occurs as a result of the combined effects of enhanced infrared (IR) absorption by the surface plasmon resonance and the inability of the nanorods to radiate at long wavelengths. This can result in the transfer of energy from a lower temperature body to a higher temperature body. This observation does not violate any thermodynamic laws as the entropy of the system is reduced with the concurrent input of energy.

2.
Vet Comp Orthop Traumatol ; 19(3): 142-6, 2006.
Article in English | MEDLINE | ID: mdl-16971996

ABSTRACT

Histological measurements of the thickness of non-calcified and calcified cartilage, as well as the subchondral bone plate in five locations on the femoral trochlea and medial femoral condyles of species were used in preclinical studies of articular cartilage and compared to those of the human knee. Cadaver specimens were obtained of six human knees, as well as six equine, six goat, six dog, six sheep and six rabbit stifle joints (the animal equivalent of the human knee). Specimens were taken from the lateral trochlear ridge, medial trochlear ridge and medial femoral condyle. After histopathological processing, the thickness of non-calcified and calcified cartilage layers, as well as the subchondral bone plate, was measured. Average articular cartilage thickness over five locations were 2.2-2.5 mm for human, 0.3 mm for rabbit, 0.4-0.5 mm for sheep, 0.6-1.3 mm for dog, 0.7-1.5 mm for goat and 1.5-2 mm for horse. The horse provides the closest approximation to humans in terms of articular cartilage thickness, and this approximation is considered relevant in pre-clinical studies of cartilage healing.


Subject(s)
Cartilage, Articular/anatomy & histology , Knee/anatomy & histology , Stifle/anatomy & histology , Animals , Dogs , Goats , Horses , Humans , Rabbits , Sheep , Species Specificity
3.
Equine Vet J ; 37(1): 81-6, 2005 Jan.
Article in English | MEDLINE | ID: mdl-15651740

ABSTRACT

REASONS FOR PERFORMING STUDY: Anecdotal reports suggest that laser-facilitated arthrodesis of the distal tarsal joints improves the prognosis compared with intra-articular drilling but no objective comparisons have been performed. OBJECTIVES: To evaluate intra-articular drilling and laser-facilitated arthrodesis using in situ and in vivo techniques. METHODS: Fourteen cadaver limbs were evaluated in situ for chondrocyte viability after both surgical techniques. In vivo, one randomly selected limb was subjected to laser-facilitated arthrodesis and the other underwent intra-articular drilling in 6 normal horses. Clinical examinations were performed at 1, 3 and 5 months. Two horses were subjected to euthanasia at 1, 3 and 5 months. RESULTS: Significantly more chondrocyte death was observed with laser-facilitated arthrodesis compared to drilling, but the overall degree suggested only a focal effect. In vivo, both groups demonstrated minimal post operative morbidity. There was more evidence of arthrodesis seen at all time points with intra-articular drilling. CONCLUSIONS: This study demonstrated that changes associated with ultimate arthrodesis occur earlier after intra-articular drilling of the distal tarsal joints than laser-facilitated arthrodesis, although clinically affected horses may respond differently. POTENTIAL RELEVANCE: Intra-articular drilling may provide earlier arthrodesis of the distal tarsal joints, but not necessarily a better long-term result.


Subject(s)
Arthrodesis/veterinary , Horse Diseases/surgery , Osteoarthritis/veterinary , Tarsal Joints/surgery , Animals , Arthrodesis/instrumentation , Arthrodesis/methods , Cadaver , Chondrocytes , Horse Diseases/pathology , Horses , Lameness, Animal/pathology , Lameness, Animal/surgery , Laser Therapy/veterinary , Microscopy, Confocal/veterinary , Osteoarthritis/pathology , Osteoarthritis/surgery , Tarsal Joints/pathology , Treatment Outcome
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