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1.
Soc Work Public Health ; 37(6): 499-509, 2022 08 18.
Article in English | MEDLINE | ID: mdl-35172697

ABSTRACT

Before the COVID-19 pandemic, questions about the increased use of telemedicine had become common in conversations among medical providers. With the onset of the pandemic, these questions became more pronounced, and quick implementation became the key. New and historic barriers to telemedicine began to emerge at a dramatically increased rate during its rapid mobilization. However, considering how quickly telemedicine has been implemented, the impact on frontline workers, such as social workers, has not been specifically explored. We wondered how the change from face-to-face care to using digital platforms for care delivery has affected social work. Could social work ensure the fluid rollout of digital treatment platforms for care management? Could social work balance the increased number of digital treatment platforms with self-care for social workers during the COVID-19 crisis? What were some history social- work-preparedness plans used for other pandemics, and would those plans work for the COVID-19 pandemic? What were some of the self-care techniques employed by social workers? What were the emerging best practices of social workers at the Department of Veterans Affairs (VA) health care system in the U.S. South? We needed to explore these questions to formulate knowledge that could be beneficial for VA health care. This literature review assesses the current responses from the field of social work during the COVID-19 pandemic, leveraging telemedicine, social work self-care, and the fluidity of VA services.


Subject(s)
COVID-19 , Telemedicine , Humans , Pandemics , SARS-CoV-2 , Self Care , Social Work , Telemedicine/methods
2.
Langmuir ; 37(47): 13961-13967, 2021 11 30.
Article in English | MEDLINE | ID: mdl-34788044

ABSTRACT

Materials taking advantage of the characteristics of biological tissues are strongly sought after in medical science and bioscience. On the natural corneal tissue surface, the highly soft and lubricated surface is maintained by composite structures composed of hydrophilic biomolecules and substrates. To mimic this structure, the surface of a silicone hydrogel contact lens was modified with a biomimetic phospholipid polymer, poly(2-methacryloyloxyethyl phosphorylcholine) (PMPC), and the nanoscaled morphology and mechanical properties of the surface were confirmed with advanced surface characterization and imaging techniques under an aqueous medium. Concavities and convexities on the nanometer order were recognized on the surface. The surface was completely covered with a PMPC layer and remained intact even after 30 days of clinical use in a human ocular environment. The mechanical properties of the natural corneal tissue and the PMPC-modified surface were similar in the living environment, that is, low modulus and frictional properties comparable to natural tissues. These results show the validity of material preparation by biomimetic methods. The methodologies developed in this study may contribute to future development of human-friendly medical devices.


Subject(s)
Contact Lenses , Hydrogels , Biomimetics , Humans , Phosphorylcholine , Polymers , Silicones , Surface Properties
3.
Colloids Surf B Biointerfaces ; 199: 111539, 2021 Mar.
Article in English | MEDLINE | ID: mdl-33387797

ABSTRACT

A silicone hydrogel contact lens material, with a unique chemical and physical structure has been designed for long-term ocular performance. Enhancement of this silicone hydrogel contact lens material was achieved through surface modification using a cross-linkable bioinspired 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer, which creates a soft surface gel layer on the silicone hydrogel base material. The surface properties of this MPC polymer-modified lens were characterized under hydrated condition revealing, inter alia, its unique polymer structure, excellent hydrophilicity, lubricity, and flexibility. Analysis of the MPC polymer layer in a hydrated state was performed using a combination of a high-resolution environmental scanning electron microscopy and atomic force microscopy. Compared to the silicone hydrogel base material, this surface had a higher captive bubble contact angle, which corresponds to higher hydrophilicity of the surface. In addition, the hydrated MPC polymer layer exhibited an extremely soft surface and reduced the coefficient of friction by more than 80 %. These characteristics were attributed to the hydration state of the MPC polymer layer on the surface of the silicone hydrogel base material. Also, interaction force of protein deposition was lowered on the surface. Such superior surface properties are anticipated to contribute to excellent ocular performance.


Subject(s)
Contact Lenses, Hydrophilic , Contact Lenses , Hydrogel, Polyethylene Glycol Dimethacrylate , Hydrogels , Methacrylates , Phosphorylcholine/analogs & derivatives , Polymers , Silicones
4.
Appl Biosaf ; 25(1): 28-40, 2020 Mar 01.
Article in English | MEDLINE | ID: mdl-36033381

ABSTRACT

Introduction: The performance of 2 disinfectant chemicals, peracetic acid (PAA) and hypochlorous acid (HOCl), was evaluated using a Venturi-nozzle-based light decontamination system (LDS) for delivery. The atomization equipment combined low-pressure air and disinfectant via a handheld lance, producing a fine, dense aerosol. A range of microorganisms, including Bacillus cereus and Bacillus anthracis (Vollum) spores, were used as test challenges to evaluate chemicals and equipment. Methods: The tests undertaken included assessments over fixed and variable exposure times, use of multiple surface materials, and a live agent challenge. Results: Over a fixed-time exposure of 60 minutes, aerosolized PAA gave 7- to 8-log reductions of all test challenges, but HOCl was less effective. Material tests showed extensive kill on most surfaces using PAA (≥6-log kill), but HOCl showed more variation (4- to 6-log). Testing using B. anthracis showed measurable PAA induced spore kill inside 5 minutes and >6-log kill at 5 minutes or over. HOCl was less effective. Discussion: The results demonstrate the importance of testing decontamination systems against a range of relevant microbiological challenges. Disinfectant efficacy may vary depending on product choice, types of challenge microorganisms, and their position in a treated area. The most effective disinfectants demonstrate biocidal efficacy despite these factors. Conclusion: The data confirmed PAA as an effective disinfectant capable of rapidly killing a range of microorganisms, including spores. HOCl was less effective. The LDS system successfully delivered PAA and HOCl over a wide area and could be suitable for a range of frontline biosecurity applications.

5.
Can Vet J ; 56(9): 971-7, 2015 Sep.
Article in English | MEDLINE | ID: mdl-26345493

ABSTRACT

We evaluated mid- to long-term outcomes with respect to function and complications in dogs undergoing canine unicompartmental elbow (CUE) arthroplasty for treatment of medial compartment disease of the elbow. This prospective multicenter case series is the first group of clinical cases to receive CUE arthroplasty. Cases (each elbow that underwent CUE performed by a participating surgeon) were enrolled into an electronic database and prospectively followed to determine and record all associated complications, as well as functional outcomes. There were 103 cases from 18 surgeons. Final follow-up time ranged from 6 to 47 mo with a mean and median of 10 mo. Canine unicompartmental elbow was associated with 1 catastrophic (1%), 11 major (10.7%), and 28 minor (27.2%) complications. Outcomes following CUE were reported as full function in 49 cases (47.6%), acceptable function in 45 cases (43.7%), and unacceptable function in 9 cases (8.7%). We conclude that CUE arthroplasty is an appropriate consideration for treatment of medial compartment disease of the elbow in dogs.


Résultats cliniques associés à l'utilisation initiale du système d'arthroplastieCanine Unicompartmental Elbow (CUE) Arthroplasty SystemMD. Nous avons évalué les résultats à long et à moyen terme relativement à la fonction et aux complications chez les chiens subissant une arthroplastie du coude unicompartimental canin (CUC) pour le traitement de la maladie compartimentale médiale du coude. Cette série prospective de cas multicentres représente le premier groupe de cas cliniques à recevoir une arthroplastie CUC. Les cas (chaque coude qui a subi une CUC réalisée par un chirurgien participant) étaient inscrits dans une base de données électroniques et suivis de manière prospective afin de déterminer et de consigner toutes les complications connexes ainsi que les résultats fonctionnels. Il y avait 103 cas provenant de 18 chirurgiens. Le temps de suivi final s'échelonnait de 6 à 47 mois avec une moyenne et une médiane de 10 mois. Le coude compartimental canin a été associé à 1 complication catastrophique (1 %), à 11 complications majeures (10,7 %) et à 28 complications mineures (27,2 %). Les résultats après l'arthroplastie CUC ont été signalés comme une fonction complète dans 49 cas (47,6 %), une fonction acceptable dans 45 cas (43,7 %) et une fonction inacceptable dans 9 cas (8,7 %). Nous avons conclu que l'arthroplastie CUC est une considération appropriée pour le traitement de la maladie compartimentale médiale du coude chez les chiens.(Traduit par Isabelle Vallières).


Subject(s)
Arthroplasty/veterinary , Compartment Syndromes/veterinary , Dog Diseases/surgery , Joint Diseases/surgery , Prostheses and Implants/veterinary , Animals , Arthroplasty/instrumentation , Cartilage, Articular/surgery , Compartment Syndromes/surgery , Dogs , Forelimb , Retrospective Studies
6.
Chem Commun (Camb) ; (21): 3059-61, 2009 Jun 07.
Article in English | MEDLINE | ID: mdl-19462086

ABSTRACT

1,4,8,11-Methyl-substituted 6,13-triethylsilylethynylpentacene shows extended pi-pi overlap when deposited from solution, yielding organic thin film transistors with high and reproducible hole mobility with negligible hysteresis.

7.
Chem Commun (Camb) ; (47): 5061-3, 2007 Dec 21.
Article in English | MEDLINE | ID: mdl-18049753

ABSTRACT

The synthesis of regioregular poly(3-hexyl)selenophene is reported, and its optical and electrical properties are compared to those of regioregular poly(3-hexyl)thiophene.


Subject(s)
Organoselenium Compounds/chemistry , Polymers/chemistry , Molecular Structure , Spectrophotometry
8.
Exp Eye Res ; 82(6): 994-1001, 2006 Jun.
Article in English | MEDLINE | ID: mdl-16318851

ABSTRACT

Glucocorticoids can alter the trabecular meshwork in the aqueous outflow pathway of the eye leading to the development of ocular hypertension and glaucoma. Previous studies have shown biochemical and ultrastructural changes in cultured human trabecular meshwork (TM) cells treated with dexamethasone (DEX). In order to assess how the membranes of these treated cells were responding to this glucocorticoid, we compared DEX-treated and control TM cells using the freeze-fracture technique. Human TM cells were grown to confluence on either Millipore HA filter inserts or glass coverslips and then treated for 14 days with or without 0.1 microM dexamethasone. The cell cultures were then aldehyde fixed and prepared for electron microscopy and freeze-fracture. Junctional complexes in control and DEX-treated cells consisted of gap junctions of various shapes and sizes. No tight junctional complexes were apparent in either control or DEX-treated cells. The majority of vesicle fusion sites on the control cells appeared to be randomly distributed and were few in number. In contrast, DEX-treated cells had a significantly greater density of fusion sites, and the majority of the vesicles were aligned into linear arrays. These findings support our previous findings of increased secretory activity in DEX-treated cultured human TM cells. These in vitro model system data appear to correlate with previous in vivo biochemical, ultrastructural and freeze-fracture data.


Subject(s)
Dexamethasone/pharmacology , Freeze Fracturing/methods , Glucocorticoids/pharmacology , Trabecular Meshwork/cytology , Adolescent , Adult , Cell Line , Cell Membrane/drug effects , Cell Membrane/ultrastructure , Gap Junctions/drug effects , Gap Junctions/ultrastructure , Glaucoma/pathology , Humans , Microscopy, Electron/methods , Middle Aged , Models, Biological , Trabecular Meshwork/drug effects , Trabecular Meshwork/ultrastructure
12.
Chem Commun (Camb) ; (11): 1465-7, 2005 Mar 21.
Article in English | MEDLINE | ID: mdl-15756337

ABSTRACT

Rigidification has been achieved in thiophene-tetrafluorophenylene architectures through strong S...F and H...F intramolecular interactions; the resulting materials are promising candidates for p-type organic field effect transistors.

18.
Nurs Times ; 100(37): 28-9, 2004.
Article in English | MEDLINE | ID: mdl-15485145
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