Subject(s)
Adenocarcinoma, Mucinous/pathology , Skin Neoplasms/pathology , Aged , Groin , Humans , MaleABSTRACT
CT and MR findings in two patients with hepatoerythropoietic porphyria are presented. CT scans showed atrophy and cortical mineralization at the same level. MR examination performed in one of the two patients showed mainly frontal cortical atrophy and punctate bright signal on T1- and T2-weighted sequences.
Subject(s)
Brain Diseases/diagnosis , Calcinosis/diagnosis , Cerebral Cortex/pathology , Porphyria, Hepatoerythropoietic/diagnosis , Tomography, X-Ray Computed , Adult , Atrophy , Epilepsy, Frontal Lobe/diagnosis , Epilepsy, Frontal Lobe/genetics , Female , Frontal Lobe/pathology , Humans , Male , Porphyria, Hepatoerythropoietic/geneticsSubject(s)
Nail Diseases/pathology , Sarcoidosis/pathology , Aged , Aged, 80 and over , Female , Humans , Male , Middle Aged , Nails/pathology , Skin Diseases/pathologyABSTRACT
Two cases affected by the nevoid basal cell carcinoma syndrome are reported herein with multiple basal cell carcinomas on exposed areas, with the previous appearance of pigmented macules on which a morphological transformation was shown with the presence of erythematous papules and plaques in a ring-like, formation made up of epitheliomatous pearls, giving the appearance of lesional polymorphism. The clinical pathological diagnosis of epithelioma basocellular is confirmed. In both patients, numerous pits on the hands and feet are shown without noticeable subjective symptoms; one of the biopsies reveals a carcinoma of basal cells in the epidermis underlying the pit. A detailed study is carried out on both families with the existence of different osseous anomalies, without finding cutaneous stigmas. The treatments carried out are checked bringing in our experience with the locally applied 5-FU. It is clearly obvious that UV light is a key factor in these two cases.
Subject(s)
Basal Cell Nevus Syndrome/pathology , Carcinoma, Basal Cell/pathology , Adult , Biopsy , Female , Humans , Jaw/diagnostic imaging , Male , RadiographyABSTRACT
We present a case which may be labeled Jadassohn's intraepidermal epithelioma, but which has led us to revise the problem of intraepidermal neoplasias, and establish whether or not this entity possesses distinct features which would permit us to differentiate it.
Subject(s)
Skin Neoplasms/diagnosis , Aged , Carcinoma, Basal Cell/diagnosis , Diagnosis, Differential , Female , Humans , Skin/pathology , Skin Neoplasms/pathologyABSTRACT
The authors present here a case report of colloid milium beginning early in the childhood , with affectation of four relatives in the same generation, suggesting a pattern of inheritance in a recessive way.
Subject(s)
Collagen Diseases/genetics , Collagen Diseases/pathology , Face , Genes, Recessive , Humans , Male , Middle Aged , Pedigree , Skin/pathologyABSTRACT
A case of LEDC is reported, with clinic, histopathological and immune-fluorescence studies. The injuries start suddenly on the face and neck with a capricious evolution, reaching a complete disappearance without leaving neither scar nor atrophy, returning in few time in zones normally not exposed to the sun, as subchin region, low neck zone and lateral aspects of the neck continuing on the level of the skin of the head. The clinic study of the injuries call to mind the form described by Gougerot in 1930 of his túmidus and by the evolution of the same, the forma described by Gougerot and Carteaud, denominating it "à eclipse".
Subject(s)
Lupus Erythematosus, Discoid/pathology , Adult , Humans , Lupus Erythematosus, Discoid/diagnosis , MaleABSTRACT
In 2 children, both 7 years old, and with an obvious presence of clinical symptoms, the diagnosis of porphyria cutanea tarda was corroborated by the characteristic patterns of urinary and fecal prophyrin excretion. Familial studies allowed us to consider both cases as hereditary.
