Subject(s)
Laboratories/organization & administration , Canada , Cost-Benefit Analysis , Decision Making, Organizational , Laboratories/economics , Laboratories/trends , Leadership , Models, Organizational , National Health Programs/economics , National Health Programs/organization & administration , Outcome Assessment, Health Care , Private Sector , Public Sector , Quality of Health CareABSTRACT
The performance of 47 patients with Parkinson's disease on a battery of tests of cognition, motor function, disability and mood was compared with the performance of 47 healthy control subjects who were matched to the patients on the basis of age, sex and pre-morbid IQ. An increased prevalence of impairment over a range of cognitive functions was observed in the Parkinson's disease patients as compared with their matched controls. The differences between the Parkinson's disease patients and controls could not be accounted for by factors such as depressed mood, effects of medication or motor impairment. Our findings are discussed in relation to the methodology of previous studies in this area and to the need for a comprehensive clinico-pathological longitudinal study.
Subject(s)
Cognition Disorders/diagnosis , Dementia/diagnosis , Neuropsychological Tests , Parkinson Disease/diagnosis , Activities of Daily Living/psychology , Affective Symptoms/diagnosis , Affective Symptoms/psychology , Aged , Cognition Disorders/psychology , Cohort Studies , Dementia/psychology , Female , Humans , Intelligence , Male , Middle Aged , Neurologic Examination , Parkinson Disease/psychology , Wechsler ScalesABSTRACT
In a comparison of assessment methods of severity of depressive illness, the Montgomery-Asberg Scale had, broadly, a performance equal to the Hamilton Scale. The Beck Depression Inventory, it subscale, and the Wakefield Inventory all had overall poor performances and should now be abandoned in research. The two-patient-rated scales were, overall, similar and fairly satisfactory measures. The comparisons were at points in severity of illness and not on change of severity.
