ABSTRACT
RESUMEN La Esclerosis Sistémica (ES) es una enfermedad autoinmune crónica con la tasa más alta de mortalidad y morbilidad entre las enfermedades reumáticas, se caracteriza por daño vascular y fibrosis tanto cutáneo como de órganos internos. Se presenta una serie de cuatro casos clínicos de pacientes femeninos ecuatorianos afectos de dicha patología, en concomitancia con otros padecimientos autoinmunes diagnosticados y en seguimiento en el Hospital General Docente de Calderón de la ciudad de Quito.
ABSTRACT Systemic sclerosis (ES) is a chronic autoimmune disease with a higher rate of mortality and morbidity among rheumatic diseases, it is vascular damage and both skin fibrosis and internal internals. We present a series of four clinical cases of Ecuadorianfemale patients affected by the said pathology, in concomitance with other autoimmune diseases, diagnosis and follow-up in the General Teaching Hospital of Calderón in the city of Quito Ecuador.
ABSTRACT
Long-acting injectable progesterone (iP4) supplementation during early diestrus is a strategy to increase conception rates in cow-calf beef operations. However, iP4 treatment causes early functional and structural regression of the corpus luteum (CL) in a proportion of iP4-treated animals, resulting in pregnancy loss. The hypothesis evaluated was that iP4 accelerates downregulation of sex-steroid receptors (PGR, ESR1, ESR2) during early to mid-diestrus and the upregulation of genes controlling PGF2α secretion (OXTR, PTGS2, AKR1B1) during late diestrus in the endometrium. Ovulations of cyclic, multiparous Nelore (Bos indicus) cows were synchronized, and cows were divided to receive placebo or 300 mg iP4 3 d postovulation (D3). Growth and vascularization of luteal tissue were evaluated by ultrasonography. Blood samples were collected from 3 d postovulation to 3 d after luteolysis, and P4 plasma concentrations were measured by radioimmunoassay. On days 3, 5, 7, 9, 11, 13, and 16 luminal endometrial samples were taken using a cytologic brush. Transcript abundance was measured by qPCR. Structural luteolysis occurred 3 d earlier in cows receiving iP4 compared to the control group. Analyzing only cows that received iP4, those that presented early luteolysis (ie, ≤ D16) showed a decrease in CL area and P4 concentration after D5, compared to the control group. Cows that presented early luteolysis showed a reduced abundance of transcripts on D5 for the ESR2 gene and a greater abundance of transcripts for OXTR and ESR1 on D16, compared to cows that did not present early luteolysis. The iP4-induced early luteolysis can be explained by two nonexclusive possibilities: the activation of uterine mechanisms that trigger early secretion of endometrial PGF pulses and the formation of a subfunctional CL that is prone to early regression.
Subject(s)
Cattle/physiology , Corpus Luteum/drug effects , Endometrium/drug effects , Progesterone/pharmacology , Animals , Corpus Luteum/physiology , Endometrium/metabolism , Female , Gene Expression Regulation/drug effects , Gene Expression Regulation/physiology , Progesterone/administration & dosage , Time FactorsABSTRACT
Anaerobic digestion of Iberian pig slaughterhouse and tomato industry wastes, as well as codigestion operations from such residues, are reported to achieve 54-80% reduction in Chemical Oxygen Demand and 6-19 N m(3)/m(3) substrate methane production. Furthermore, 0.79-0.88 m(3)water/m(3) substrate is seen to be recovered after the above mentioned operations, which might be used as irrigation water, and 0.12-0.21 m(3)agricultural amendment/m(3) substrate with 91-98% moisture content. The present paper also reports on the economic feasibility of both an anaerobic codigestion plant operating with 60% slaughterhouse wastes/40% tomato industry wastes (optimal ratio obtained in previous laboratory-scaled experiments), and an anaerobic digestion plant for Iberian pig slaughterhouse waste. Payback times are reported as 14.86 and 3.73 years, respectively.
Subject(s)
Abattoirs , Conservation of Energy Resources/economics , Industrial Waste/analysis , Industrial Waste/economics , Refuse Disposal/economics , Refuse Disposal/methods , Solanum lycopersicum/chemistry , Alkalies/analysis , Anaerobiosis , Animals , Biodegradation, Environmental , Bioreactors , Costs and Cost Analysis , Electricity , Fatty Acids, Volatile/analysis , Feasibility Studies , Hydrogen-Ion Concentration , Sus scrofaABSTRACT
A fast and accurate (to any required precision) numerical method is presented to calculate the vapour-liquid equilibrium for any subcritical temperature from a given equation of state. The calculations are made using the popular program MATHEMATICA, and we think that this method could be very useful in chemical physics and chemical engineering applications, as well as for teaching purposes.
ABSTRACT
En este trabajo se destacan las ventajas e inconvenientes del uso de diversos patrones estadísticos, que van desde los más tradicionales hasta los más recientes, concluyendo que la aplicación de la teoría de los sistemas dinámicos no lineales es la más adecuada para el estudio de los TCAs en pacientes infanto juveniles, ya que nos aporta la mayor cantidad de información posible sobre la evolución de este tipo de trastornos, permitiéndonos cuantificar, modelar, e incluso predecir las conductas de estos pacientes (AU)
Subject(s)
Adolescent , Child , Humans , Linear Models , Feeding and Eating Disorders/epidemiology , Clinical Evolution , Nonlinear Dynamics , Epidemiology, Descriptive , Feeding and Eating Disorders/diagnosisABSTRACT
The validity of analytical equations for two-dimensional fluids in the prediction of monolayer adsorption isotherms and spreading pressures of rare gases on graphite is analyzed. The statistical mechanical theory of Steele is used to relate the properties of the adsorbed and two-dimensional fluids. In such theory the model of graphite is a perfectly flat surface, which means that only the first order contribution of the fluid-solid interactions are taken into account. Two analytical equations for two-dimensional Lennard-Jones fluids are used: one proposed by Reddy-O'Shea, based in the fit on pressure and potential energy computer simulated results, and other proposed by Cuadros-Mulero, based in the fit of the Helmholtz free energy calculated from computer simulated results of the radial distribution function. The theoretical results are compared with experimental results of Constabaris et al. (J. Chem. Phys. 37, 915 (1962)) for Ar and of Putnam and Fort (J. Phys. Chem. 79, 459 (1975)) for Kr. Good agreement is found using both equations in both cases.
