ABSTRACT
As the south-westernmost region of Europe, the Iberian Peninsula stands as a key area for understanding the process of modern human dispersal into Eurasia. However, the precise timing, ecological setting and cultural context of this process remains controversial concerning its spatiotemporal distribution within the different regions of the peninsula. While traditional models assumed that the whole Iberian hinterland was avoided by modern humans due to ecological factors until the retreat of the Last Glacial Maximum, recent research has demonstrated that hunter-gatherers entered the Iberian interior at least during Solutrean times. We provide a multi-proxy geoarchaeological, chronometric and paleoecological study on human-environment interactions based on the key site of Peña Capón (Guadalajara, Spain). Results show (1) that this site hosts the oldest modern human presence recorded to date in central Iberia, associated to pre-Solutrean cultural traditions around 26,000 years ago, and (2) that this presence occurred during Heinrich Stadial 2 within harsh environmental conditions. These findings demonstrate that this area of the Iberian hinterland was recurrently occupied regardless of climate and environmental variability, thus challenging the widely accepted hypothesis that ecological risk hampered the human settlement of the Iberian interior highlands since the first arrival of modern humans to Southwest Europe.
Subject(s)
Human Migration/history , Animals , Archaeology , Bayes Theorem , Charcoal/history , Climate , Environment , Fossils/history , Geologic Sediments/analysis , Geological Phenomena , History, Ancient , Humans , Models, Biological , Pollen/chemistry , Population Dynamics/history , Radiometric Dating , Spain , Vertebrates , Wood/historyABSTRACT
No disponible
Subject(s)
Humans , Bilirubin/biosynthesis , Hyperbilirubinemia/physiopathology , Erythrocytes/ultrastructure , Erythrocyte Aggregation , Free Radicals/analysis , AntioxidantsABSTRACT
Se aportan tres casos de carotenodermia dietética tras la ingestión abundante de alimentos ricos en carotenos (zanahorias, naranjas). Se trata de dos varones y una mujer, adultos jóvenes, dos de ellos con antecedentes psicopatológicos. El principal problema clínico que plantean es la posible confusión con ictericias, aunque la pigmentación es sólo cutánea, no de escleróticas, la tonalidad es amarillo-anaranjada y la determinación de bilirrubina normal. La confirmación del diagnóstico se hace por la cuantificación de carotenos, que están elevados (AU)
There are three cases of dietetic carotenodermia after the great ingestion of food which is rich in carotenoids (carrot, oranges). There are two men and a woman, they are young adults, two of them have previous psicopathologics. The main clinic problem which appears is the possible mistake with icterics, although the pigmentation is only in this case skin, the pigmentation is not of eschlerotics, the shade of the skin is yellow- orange and the determination of normal billirubin. The confirmation of the diagnostic is made by the quantification of carotenes which are raised (AU)
Subject(s)
Humans , Male , Female , Young Adult , Adult , Carotenoids/adverse effects , Pigmentation Disorders/diagnosis , Jaundice/diagnosis , Diagnosis, Differential , Daucus carota/adverse effectsABSTRACT
Objetivos: analizar la actividad asistencial en una unidad de Medicina Interna del Hospital Clínico Universitario de Granada. Casuística. Métodos: se estudian367 enfermos ingresados durante el años 1998 en una unidad de 18 camas. Se examinó el informe de alta o epicrisis de todos los pacientes, protocolizando la edad, sexo, diagnósticos principal y secundarios, mortalidad intrahospitalaria, traslado a otros servicios. Resultados: 202 (55%) pacientes eran varones y 165 (45%) mujeres. Hubo un neto predominio de las edades avanzadas con una media de 74±3 años. El motivo de ingreso fue por orden de frecuencia: cardiovascular respiratorio y neurológico. La mitad de los pacientes tenía 5 ó más diagnósticos al alta. La mortalidad fue del 11% (41 casos). Conclusiones: en el servicio de Medicina Interna ingresan la mayor parte de pacientes con edades muy avanzadas portadores de pluripatologías, siendo la mortalidad muy elevada
Aim: to analyse the activity in an Internal Medicine Unit in the Clinic Universitary Hospital of Granada. Patients. Methods: 367 patients was admitted in 1998 in 18 beds unit. We study the discharged report. Results: 202 (55%) men and 165 (45%) women. Many patients was very old, with a median age of 74±3 years. The main causes of hospitalization was cardiovascular, respiratory and neourologic disease. Half of patients had 5 or more diagnoses when they were discharged. Mortality was 11% (41 cases).Conclusions: most of the patients in a Internal medicine Unit was old people, with many diseases and a high mortality
Subject(s)
Humans , Male , Female , Aged , Hospitalization/statistics & numerical data , Internal Medicine/statistics & numerical data , Morbidity/trends , Hospital Departments/statistics & numerical data , Spain , Hospital Statistics , Hospital Mortality , Age Distribution , Sex DistributionSubject(s)
Bacteremia/complications , Iron/blood , Liver Cirrhosis/complications , Yersinia Infections/complications , Yersinia enterocolitica , Bacteremia/diagnosis , Biopsy , Humans , Liver/pathology , Liver Cirrhosis/diagnosis , Liver Cirrhosis/pathology , Male , Middle Aged , Yersinia Infections/diagnosisABSTRACT
No disponible
Subject(s)
Middle Aged , Aged , Male , Female , Humans , Yersinia enterocolitica , Retroperitoneal Space , Yersinia Infections , Bacteremia , Biopsy , Anticoagulants , Diagnosis, Differential , Acenocoumarol , Iron , Liver Cirrhosis , Liver , HematomaABSTRACT
Ten new cases of hereditary hemorrhagic telangiectasia (Rendu-Osler-Weber's disease) are presented. Five of them were detected among 30,000 patients attending a Service of Internal Medicine; the remainder five, were detected while conducting the family study. Epistaxis (5 cases) and hidden (2 cases) and evident (1 case) digestive hemorrhage were the most frequent clinical signs. All patients presented telangiectasia affecting lips. We observed edemas in nasal fossas (5 cases), hand fingers (6 cases), tongue (2 cases) and face (1 case), as well as in gastroduodenal mucosa in the three patients undergoing endoscopic study. We did not observed hemostasis disorders, except for moderate thrombocytosis in two patients and microcytic anemia in three patients. The relevance of clinical evaluation is stressed, because all patients presented oral-facial telangiectasia.
