ABSTRACT
Mazabraud syndrome was first described in 1926 by Henschen, consisting of the association between bone fibrodysplasia and one or more intramuscular myxomas. The study paper conducted by Mazabraud et al. in 1967, described an association between the two pathologies. Later literature referred to this relationship with the eponym described above. In this report, we present the case of a 43-year-old female patient with a known diagnosis of bone fibrodysplasia and subsequent development of a right antecubital fossa mass, which was histologically confirmed as intramuscular myxoma. After the removal of the tumor, the literature was reviewed to find a possible relationship between myxomas and fibrous bone dysplasia, finding positive the association, referred to in the documents reviewed as Mazabraud syndrome.
El síndrome de Mazabraud fue descrito inicialmente en 1926 por Henschen, consiste en la asociación entre fibrodisplasia ósea y uno o más mixomas intramusculares. El documento de estudio realizado por Mazabraud y colaboradores en 1967 describió una asociación entre las dos patologías. Literatura posterior se refirió a esta relación con el epónimo antes descrito. En este reporte, presentamos el caso de una mujer de 43 años, con diagnóstico conocido de fibrodisplasia ósea y posterior desarrollo de una masa en fosa antecubital derecha, la cual fue confirmada histológicamente como mixoma intramuscular. Después de la extracción de la tumoración, se revisó la literatura para encontrar una posible relación entre mixomas y displasia ósea fibrosa, encontrando positiva la asociación, denominada en los documentos revisados como síndrome de Mazabraud.
Subject(s)
Fibrous Dysplasia of Bone , Fibrous Dysplasia, Polyostotic , Muscle Neoplasms , Myxoma , Adult , Female , Humans , Magnetic Resonance Imaging , Muscle Neoplasms/diagnostic imaging , Myxoma/diagnosis , Myxoma/surgery , SyndromeABSTRACT
Penile carcinoma is a rare disease that has a wide range of pathology and morbidity. Occurs commonly in the 6th and 7th decades of life. Squamous cell carcinoma (SCC) is the predominant histological type. We present a case of a penile lesion of exophytic papillary morphology accompanied by multiple bilateral mobile inguinal lymph nodes.
Subject(s)
Carcinoma, Papillary/pathology , Carcinoma, Papillary/surgery , Carcinoma, Squamous Cell/pathology , Carcinoma, Squamous Cell/surgery , Penile Neoplasms/pathology , Penile Neoplasms/surgery , Aged , Humans , Lymphatic Metastasis , Male , Neoplasm Invasiveness , Neoplasm Staging , Penis/surgery , Treatment Outcome , Urethra/surgeryABSTRACT
INTRODUCTION: Prostatic adenocarcinomas have a marked tendency to spread to lymph nodes and bones, with occasional internal organ metastases. Brain metastases from prostatic carcinomas are rare. CASE REPORT: We report the case of a patient with haemorrhagic brain metastasis from prostatic adenocarcinoma, which was initially considered to be a parenchymatous brain haemorrhage. The possible ways by which it can spread, the difficulty involved in interpreting the images and the role played by a biopsy with immunostaining in reaching a final diagnosis are also discussed. CONCLUSIONS: Perhaps the most significant aspect of this case was the 13 year period that elapsed between diagnosis of the primary tumour and brain metastasis, the absence of spreading to lymph nodes and the localised, intrapelvic, aspect of the bone lesion that was detected.
