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1.
Clin Pediatr (Phila) ; 61(12): 850-858, 2022 12.
Article in English | MEDLINE | ID: mdl-35773977

ABSTRACT

Licensed behavioral health providers (LBHPs) were integrated into 5 pediatric primary care practices in southeast and east Texas from October 2018 through March 2020. LBHPs Licensed behavioral health providers across the sites were 3 licensed clinical social workers (LCSW), 1 psychologist, and 1 nurse practitioner (NP). Practices provided data for 6 to 15 months. Overall, 2769 units of behavioral health services were provided to 746 children over 2243 hours. Across 4 sites, 44.3% of behavioral health patients were diagnosed with trauma disorders, 22.1% with anxiety, 19.3% with attention-deficit hyperactivity disorder, 15.1% with depression, and 10.9% with disruptive behavior disorders. Overall, the model was financially successful at 2 sites (LCSWs) and unsuccessful at 1 site (NP). The other 2 sites demonstrated potential for financial sustainability with increased behavioral health patient volume. Overall, this model is a financially viable option for pediatric primary care practices with adequate patient volumes to provide integrated behavioral health services.


Subject(s)
Attention Deficit Disorder with Hyperactivity , Primary Health Care , Child , Humans , Attention Deficit and Disruptive Behavior Disorders , Anxiety , Texas
2.
J Bacteriol ; 177(18): 5322-6, 1995 Sep.
Article in English | MEDLINE | ID: mdl-7665521

ABSTRACT

Homologs of ntrB and ntrC genes from Rhodospirillum rubrum were cloned and sequenced. A mutant lacking ntrBC was constructed, and this mutant has normal nitrogenase activity under nif-derepressing conditions, indicating that ntrBC are not necessary for the expression of the nif genes in R. rubrum. However, the post-translational regulation of nitrogenase activity by ADP-ribosylation in response to NH4+ was partially abolished in this mutant. More surprisingly, the regulation of nitrogenase activity in response to darkness was also affected, suggesting a physiological link between the ntr system and energy signal transduction in R. rubrum. The expression of glutamine synthetase, as well as its posttranslational regulation, was also altered in this ntrBC mutant.


Subject(s)
Bacterial Proteins/genetics , DNA-Binding Proteins/genetics , Genes, Bacterial , Nitrogen Fixation/genetics , Nitrogenase/metabolism , Phosphoprotein Phosphatases/genetics , Protein Kinases/genetics , RNA-Binding Proteins , Rhodospirillum rubrum/genetics , Trans-Activators , ADP Ribose Transferases/metabolism , Amino Acid Sequence , Cloning, Molecular , Darkness , Gene Expression Regulation, Bacterial/genetics , Glutamate-Ammonia Ligase/biosynthesis , Molecular Sequence Data , Mutation , PII Nitrogen Regulatory Proteins , Quaternary Ammonium Compounds/pharmacology , Rhodospirillum rubrum/enzymology , Sequence Analysis, DNA , Sequence Deletion , Signal Transduction , Transcription Factors/genetics
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