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1.
An Bras Dermatol ; 93(1): 116-118, 2018.
Article in English | MEDLINE | ID: mdl-29641711

ABSTRACT

Subcorneal pustular dermatosis is a rare pustular eruption which occurs mainly in middle-aged women and rarely during childhood. We report a case of a 15-year-old female with a 4-year history of pustular lesions on the proximal region of the upper limbs with subsequent impairment of the trunk. Physical examination revealed small pustules distributed on the trunk and proximal region of the limbs. Histopathology showed a subcorneal pustule and direct immunofluorescence for IgA, IgM, IgG and fibrinogen was negative, confirming the diagnosis of subcorneal pustular dermatosis. The patient was treated with dapsone with good clinical response after one month. Subcorneal pustular dermatosis is a rare condition and there are only isolated cases reported in the literature in pediatric patients. Thus, we discuss the main clinical aspects and treatment response of this condition during childhood.


Subject(s)
Dapsone/therapeutic use , Dermatologic Agents/therapeutic use , Skin Diseases, Vesiculobullous/drug therapy , Adolescent , Bilirubin/blood , Female , Hemoglobins/analysis , Humans , Skin Diseases, Vesiculobullous/diagnosis , Skin Diseases, Vesiculobullous/pathology
2.
An. bras. dermatol ; 93(1): 116-118, Jan.-Feb. 2018. graf
Article in English | LILACS | ID: biblio-887165

ABSTRACT

Abstract: Subcorneal pustular dermatosis is a rare pustular eruption which occurs mainly in middle-aged women and rarely during childhood. We report a case of a 15-year-old female with a 4-year history of pustular lesions on the proximal region of the upper limbs with subsequent impairment of the trunk. Physical examination revealed small pustules distributed on the trunk and proximal region of the limbs. Histopathology showed a subcorneal pustule and direct immunofluorescence for IgA, IgM, IgG and fibrinogen was negative, confirming the diagnosis of subcorneal pustular dermatosis. The patient was treated with dapsone with good clinical response after one month. Subcorneal pustular dermatosis is a rare condition and there are only isolated cases reported in the literature in pediatric patients. Thus, we discuss the main clinical aspects and treatment response of this condition during childhood.


Subject(s)
Humans , Female , Adolescent , Skin Diseases, Vesiculobullous/drug therapy , Dapsone/therapeutic use , Dermatologic Agents/therapeutic use , Bilirubin/blood , Hemoglobins/analysis , Skin Diseases, Vesiculobullous/diagnosis , Skin Diseases, Vesiculobullous/pathology
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